A5103284192- Inflammatory Bowel Disease
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Microscopic Colitis
- Autoimmune and Inflammatory Disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Diverticular Disease and Complications
- MRI in cancer diagnosis
- Ultrasound and Hyperthermia Applications
- Cardiac Imaging and Diagnostics
- Helicobacter pylori-related gastroenterology studies
- Radiomics and Machine Learning in Medical Imaging
- Viral gastroenteritis research and epidemiology
- Pancreatic and Hepatic Oncology Research
- Photoacoustic and Ultrasonic Imaging
Kyorin University
2021-2024
Kissei Pharmaceutical (Japan)
2024
Nippon Kayaku (Japan)
2024
Mochida Pharmaceutical (Japan)
2024
Takeda (Japan)
2024
Zeria Pharmaceutical (Japan)
2024
Bristol-Myers Squibb (Germany)
2024
EA Pharma (Japan)
2024
Pfizer (United Kingdom)
2024
Mitsubishi Tanabe Pharma Corporation
2024
Objective. Ultrasonography (US) is a simple, inexpensive and minimally invasive method. We evaluated the vascularity of small intestinal lesions in Crohn's disease using color Doppler US (CD-US) retrospectively compared them with endoscopic surgical macroscopic findings. Material methods. In order to compare CD-US findings, 108 patients who underwent examination terminal ileum by both colonoscopy were included study. Vascularity was semiquantitative method, Limberg score. analyzed...
Abstract Background Crohn’s disease (CD) is routinely evaluated using clinical symptoms, laboratory variables, and the CD activity index (CDAI). However, parameters are often nonspecific do not precisely reflect actual of small-intestinal lesions. The purposes this prospective study were to compare color Doppler ultrasound (US) findings with histological from surgically resected specimens confirm hypothesis that US can distinguish tissue inflammation fibrosis. Methods Among 1764 consecutive...
Flow characteristics of hepatic tumors at color Doppler sonography: correlation with arteriographic findings.K Numata, K Tanaka, Mitsui, M Morimoto, S Inoue and H YonezawaAudio Available | Share
Using Contrast-Enhanced Sonography to Assess the Effectiveness of Transcatheter Arterial Embolization for Hepatocellular CarcinomaKazushi Numata1, Katsuaki Tanaka1, Takayoshi Kiba1, Satoru Saito1, Tetsuo Isozaki1, Koji Hara1, Manabu Morimoto1, Hisahiko Sekihara1, Hiromi Yonezawa2 and Toru Kubota3Audio Available | Share
BackgroundUlcerative colitis (UC) occurs in young patients and is characterised by remitting relapsing episodes. Evaluation of the colorectal mucosa with colonoscopy (CS) gold standard technique for determination treatment. However, CS can be burdensome to both physicians. Transabdominal ultrasonography (TAUS) may become an alternative because it non-invasive, well accepted patients, has excellent spatial resolution. This study was performed identify US parameters that predict UC endoscopic...
Abstract Background Endoscopic improvement (EI), Mayo endoscopic subscore of 0 or 1, is considered a therapeutic target in ulcerative colitis (UC) treatment. The potential to estimate EI non-invasively an advantage intestinal ultrasound (IUS). In former study, we developed new parameter, the submucosal index (SMI), calculated as ratio thickness submucosa bowel wall (BWT), and reported that combining BWT SMI could be practical criterion for estimating without assessment vascularity using...
Abstract Background Today molecular-targeted medications (MTMs) are widely used for ulcerative colitis (UC). Predicting the efficacy of MTMs early after induction remains a crucial clinical challenge. Intestinal ultrasound (IUS) is now considered non-invasive, promising monitoring tool UC. It can assess disease activity UC in whole colon safely and repeatedly. Here, we hypothesized that over time IUS assessment predict MTM early, contribute to decision-making on whether continue or switch...
Background and Aims: Predicting the efficacy of molecular-targeted drugs (MTDs) is an unmet need in treatment ulcerative colitis (UC).Intestinal ultrasound (IUS) can be used to safely repeatedly assess UC activity. Methods: Thirty-eight patients who started MTD therapy for active underwent IUS at baseline 3 months after starting were analyzed.Steroid-free clinical remission (SFCR) endoscopic improvement (EI) 6 defined as a Lichtiger index ≤3 Mayo subscore ≤1 while continuing without steroid...
The aim of this study is to clarify whether trans-abdominal ultrasound (TAUS) can reflect actual intestinal conditions in Crohn's disease (CD) as effectively water-immersion (WIUS) does. This retrospective enrolled 29 CD patients with 113 lesions. Five (US) parameters (distinct presence/indistinct presence/disappearance wall stratification the submucosal and mucosal layers; thickened layer; irregular surface; increased fat wrapping around bowel wall; fistula signs) that may indicate...
Objectives: Transabdominal ultrasonography is a common and accurate tool for managing Crohn’s disease (CD); however, the significance of resulting data poorly understood. This study was performed to determine association between bowel wall thickness evaluated by water-immersion macroscopic severity, namely, refractory inflammation subsequent fibrosis in CD surgical specimens.Materials methods: We retrospectively 100 segments colon small intestine from 27 patients with CD. The resected...
The mean time of UC evolution until MSZ withdrawal was 7.1 ± 6.0y.MSZ treatment maintained during a median 48 months (mean dose 1.9 0.9g per day), and 34.3% patients were on topical that also withdrawn.Reasons for withdrawing long-term remission (n = 15; 42.9%, 84.0 47.5 months), patient's choice 18; 51.4%), side effects 2; 5.7%).Globally, 57.1% had at least one flare after period without (median to first 27 (IQR 8-78); 71.4% relapse the year follow-up); 40% required oral...
Abstract Background Intestinal ultrasound (IUS) is non-invasive and can assess all segments of the colon even in severe ulcerative colitis (UC). While IUS estimate endoscopic findings UC, terms Treat to Target strategy, it remains a crucial clinical question whether changes with therapeutic interventions predict treatment efficacy patient prognosis. Here, we investigated if comparing at baseline 3 months after starting molecular-targeted medication (MTM) steroid-free remission (SFCR) UC 6...
Abstract Background A less invasive examination that can estimate endoscopic remission is needed. Intestinal ultrasound (IUS) a promising option. The bowel wall thickness (BWT) widely-accepted objective parameter in IUS to assess colonic inflammation, but BWT influenced by intestinal peristalsis and the volume of luminal content. feasible, index not affected these factors could improve diagnostic potential IUS. submucosa, which observed as third layer on IUS, becomes swollen standing out...