A5100321547- Viral Infections and Immunology Research
- Cardiac electrophysiology and arrhythmias
- Respiratory viral infections research
- Cardiovascular Function and Risk Factors
- Animal Disease Management and Epidemiology
- Genetics and Neurodevelopmental Disorders
- Wnt/β-catenin signaling in development and cancer
- Atrial Fibrillation Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Advanced Proteomics Techniques and Applications
- ECG Monitoring and Analysis
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Luminescence Properties of Advanced Materials
- Animal Virus Infections Studies
- Cardiovascular Health and Risk Factors
- Cardiac Arrhythmias and Treatments
- Viral gastroenteritis research and epidemiology
- Hormonal Regulation and Hypertension
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Pediatric Hepatobiliary Diseases and Treatments
- Pain Management and Treatment
- Nuclear materials and radiation effects
- Retinal Imaging and Analysis
XinHua Hospital
2014-2025
Shanghai Jiao Tong University
2024-2025
State Key Laboratory of Oncogene and Related Genes
2024-2025
Sichuan University
2025
Central South University
2023-2024
Hefei University of Technology
2020-2024
Institute of Microbiology
2024
Second Xiangya Hospital of Central South University
2023-2024
Mianyang Central Hospital
2024
Beijing Anzhen Hospital
2023
Objectives: Autonomic dysfunction is a common symptom of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis; however, it has been poorly researched. The purpose this study was to compare the clinical features, tumor occurrence, intensive care unit (ICU) admission, mechanical ventilation, imaging assessment, cerebrospinal fluid examination, disease severity, and immunotherapy in patients with anti-NMDAR encephalitis or without autonomic dysfunction. Methods: A retrospective diagnosed...
Myocardial infarction (MI) is one of the most common cardiovascular diseases, frequently resulting in death. Early and accurate diagnosis therefore important, electrocardiogram (ECG) a simple effective method for achieving this. However, it requires assessment by specialist; so many recent works have focused on automatic ECG signals.
Identifying effective biomarkers has long been a persistent need for early diagnosis and targeted therapy of disease. While mass spectrometry-based label-free proteomics with trace cell demonstrated, deep ultratrace human biofluid remains challenging due to low protein concentration, extremely limited patient sample volume, substantial contact losses during preprocessing. Herein, we proposed validated lanthanide metal–organic framework flowers (MOF-flowers), as materials, trap enrich in...
The implementation of COVID-19 policy and the rapid development SARS-CoV-2 vaccines in early pandemic significantly contained numerous outbreaks reduced severity mortality COVID-19. However, population immunity induced by existing was insufficient to prevent outbreaks. host wide spread Omicron variants its influence on emerging are attracting broad attention. In this study, a clinical data analysis patients indicated that pre-vaccination inflammatory responses mitigated cases caused natural...
Coxsackievirus A16 (CVA16) is responsible for nearly 50% of all the confirmed hand, foot, and mouth disease (HFMD) cases in mainland China, sometimes it could also cause severe complications, even death. To clarify genetic characteristics epidemic patterns CVA16 comprehensive bioinfomatics analyses were performed by using 35 whole genome sequences from 1998 to 2011, 593 complete VP1 1981 prototype strains human enterovirus species A (EV-A). Analysis on revealed that subgenotypes B1a B1b...
Background The relationship between poor oral health conditions and cognitive decline is unclear. Objective To examine the association cognition in humans rats. Methods In humans: a cross-sectional study was conducted. Cognitive levels were evaluated by Mini Mental State Examination (MMSE); reflected number of missing index teeth, bleeding on probing, probing pocket depth (PD). rats: ligature-induced (Lig) periodontitis model Aβ25-35-induced Alzheimer's disease (AD) established; tumor...
This study aims to compare the clinical efficacy and safety between ultrasound (US)-guided percutaneous microwave ablation (MWA) assisted with a three-dimensional (3D) visualization preoperative planning system surgical resection (SR) for hepatocellular carcinoma (HCC) in caudate lobe.Forty-nine patients diagnosed lobe HCC, who underwent US-guided MWA (29 patients) or SR (20 patients), were enrolled November 2005 December 2018. Follow-up was performed at 1, 3, 6, 12, 18, 24, 36 months after...
Hormone replacement therapy (HRT) plays an important role in the treatment and prevention of osteoporosis. Here, 17β-estradiol (E2)-loaded PEGlyated upconversion nanoparticles (E2-UCNP@pPEG) were synthesized that retained E2 bioactivity improved delivery efficiency over a relatively long time-period. E2-UCNP@pPEG was characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR), among other methods. The loading determined to be 14.5 wt...
Label-free proteomics is widely used to identify disease mechanism and potential therapeutic targets. However, deep with ultratrace clinical specimen remains a major technical challenge due extensive contact loss during complex sample pretreatment. Here, hybrid of four boronic acid-rich lanthanide metal-organic frameworks (MOFs) high protein affinity introduced capture proteins in samples jointly by nitrogen-boronate complexation, cation-π ionic interactions. A MOFs Aided Sample Preparation...
Abstract Background To identify and describe the use of Grading Recommendations, Assessment, Development Evaluation (GRADE) approach for rating certainty systematic reviews (SRs) evidence published in urology nephrology journals. Methods SRs that were top ten "urology nephrology" journals with highest impact factor according to 2020 Journal Citation Reports (covering 2016–2020) systematically searched evaluated using GRADE approach. Results A total 445 researched. Sixty randomized control...
Patients with heart failure preserved ejection fraction (HFPEF) account for ~50% of all cases and their clinical prognosis is poor. The present study attempted to investigate the diagnostic value circulating long non‑coding RNA taurine upregulated gene 1 (TUG1) HFPEF in subjects hypertension. Between January 2017 2019, 80 aged/elderly hypertensive patients or without were recruited study. concentration N‑terminal pro‑brain natriuretic peptide (NT‑proBNP) serum was measured using ELISA TUG1...
Objective We aimed to study the cut-off values of estimated glomerular filtration rate (eGFR) and urinary albumin creatinine ratio (UACR) in normal range for diabetic kidney disease (DKD). Methods In this study, we conducted a retrospective, observational cohort included 374 type 2 patients who had baseline eGFR ≥60 mL/min/1.73 m UACR <30 mg/g with up 6 years follow-up. The results were further validated multi-center, prospective study. Results development cohort, (AUC: 0.90, value:...
A functional vascular system is a prerequisite for bone repair as disturbed angiogenesis often causes non-union. Paracrine factors released from human marrow derived mesenchymal stromal cells (BMSCs) have angiogenic effects on endothelial cells. However, whether these paracrine participate in blood flow dynamics within capillaries remains poorly understood. Here, we used two different microfluidic designs to investigate critical steps during and found pronounced of cell proliferation well...