A5048329806- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Head and Neck Cancer Studies
- Tracheal and airway disorders
- Gynecological conditions and treatments
- Intraperitoneal and Appendiceal Malignancies
- Gestational Trophoblastic Disease Studies
- Cervical Cancer and HPV Research
- Older Adults Driving Studies
- Sarcoma Diagnosis and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Urban Green Space and Health
- Ectopic Pregnancy Diagnosis and Management
- Spatial Cognition and Navigation
- Ovarian function and disorders
- Minimally Invasive Surgical Techniques
- Radiomics and Machine Learning in Medical Imaging
- Ear and Head Tumors
- Congenital Diaphragmatic Hernia Studies
- Maternal and fetal healthcare
- Reconstructive Surgery and Microvascular Techniques
- Pregnancy-related medical research
- Oral and Maxillofacial Pathology
Kindai University
2014-2023
Juntendo University
2001-2021
University College London
2017-2020
Kitasato University
2016-2020
National Defense Medical College Hospital
2015-2019
UK Dementia Research Institute
2017
Beijing Obstetrics and Gynecology Hospital
2017
Sapporo Kosei General Hospital
2016
National Defense Medical College
2014
Kyoto University
2004-2013
Abstract Aim Open myomectomy (OM) was previously frequently performed; however, laparoscopic (LM) has recently become more common. Nevertheless, myoma can recur after both LM and OM. In this study, we report our retrospective investigation of recurrence by comparing Methods A total 474 patients underwent 279 The were followed‐up postoperatively from six months to eight years. Recurrence confirmed when a with diameter ≥ 1 cm detected. Post‐LM, post‐OM cumulative rates investigated, Cox hazard...
Abstract The relationship between bacterial vaginosis (BV) and preterm delivery has become well known in recent years, although there are few studies on: (i) the differences test results during early gestational (EGP) middle (MGP) periods; (ii) significance of intermediate (I) group that does not develop overt BV; or (iii) therapeutic effects metronidazole. We performed a retrospective study to analyze vaginal status rate. Without treatment, rate was higher BV subgroup than I normal (N)...
The activation of JAK2/STAT3 pathway has been reported to have critical roles in several solid tumors. present study aimed evaluate the correlation between and clinicopathological parameters ovarian cancer types. Tissue microarrays made from patients treated at National Defense Medical College Hospital 1984 2008 were evaluated using immunohistochemical (IHC) stainings. charts these including IHC results retrospectively analyzed, prognostic factors for progression‑free survival overall...
The pretreatment neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte (PLR) have been reported to be useful as markers for prognostic factors metastasis in several cancers. aim of this study was identify predictor lymph node (LN) by NLR PLR patients with endometrial cancer.Medical charts cancers that received primary surgery at our hospital between 2007 2013 were retrospectively analyzed. cutoff value calculated from receiver operating characteristics (ROC) curve....
X-chromosome-linked inhibitor of apoptosis (XIAP) is one the anti-apoptotic proteins leading to chemoresistance in several cancers. The aim this study evaluate impact XIAP expression upon ovarian clear cell carcinoma (CCC) that has a platinum-resistant phenotype. Tissue microarrays made from 90 CCC patients were analysed for immunohistochemical levels XIAP, c-Met, p-Akt and Bcl-XL. In addition, lines evaluated whether silencing could modulate sensitivity platinum agent vitro. High was...
Abstract Background This study aimed to investigate the association between clinicopathologic factors, mesothelin, and cancer antigen (CA) 125 in endometrial carcinoma. Methods Between 1989 2017, patients with carcinoma who underwent total hysterectomy bilateral salpingo-oophorectomy at our hospital were identified. The either or both immunochemical expression of mesothelin CA125 clinicopathological features retrospectively examined. Results Among 485 patients, 171 positive for 368 CA125,...
High-temperature-required protein A2 (HtrA2), a relating with apoptosis in caspases-dependent and non-dependent manner, has been reported to be associated chemosensitivity several human cancers.Tissue microarrays made from 142 patients high-grade serous ovarian adenocarcinoma were evaluated assess whether HtrA2 expression was related clinical parameters.Negative observed 36 cases (25%) of the patients, significantly lower response rates primary chemotherapy than those positive (56% vs 83%,...
In an attempt to clarify the clinical characteristics of synchronous primary endometrial and ovarian cancer (SPC), we reviewed clinicopathological features 13 cases treated in Department Gynecology Obstetrics at Kyoto University Hospital over last 6 years compared them with 186 uterine corpus (PCC) 136 (POC). Comparisons were performed based on factors, including age, BMI, parity, complication thrombosis FIGO stage. For SPC patients, mean age was 51.5 years; (46%) nulliparous, 7 (53%) had...
Abstract Solitary fibrous tumor (SFT), which was first described as a pleural lesion by Klemperer and Rabin in 1931, is rare, slow‐growing neoplasm characterized the proliferation of fibroblast‐like spindle cells arranged patternless manner with few nuclear atypia. Extrathoracic SFT have increasingly been recognized, but those genital tract are extremely rare. Gynecological behave tumors low malignant potential to recur, metastasize, or affect nearby organs resulting infertility. We report...
Malignant struma ovarii is a rare type of ovarian tumor. Metastasis from malignant and has only been documented in 5‑6% cases. The natural history optimal treatment strategy for remains controversial due to its rarity. current report presents the case 45‑year‑old female who presented with tumor rib bone. Following resection, postoperative diagnosis was metastasizing thyroid carcinoma. No abnormality detected gland, however, computed tomography revealed left ovary. patient underwent...
Sentinel lymph node (SLN) mapping using dye or radioisotopes has been performed in patients with uterine cancer. Superparamagnetic iron oxide (SPIO) can be handled safely and is taken up by nodes (LNs); however, its efficacy detecting SLNs cancer remains unknown. This pilot study evaluated the use of SPIO as a tracer for SLN detection was injected into cervixes 15 scheduled pelvic LN dissection. Magnetic resonance imaging (MRI) preoperatively. Five also underwent radioisotope injection...
The aim of this study was to investigate the impact radiologic experience on diagnostic accuracy computed tomography (CT) vs. magnetic resonance imaging (MRI) reporting liver metastases pancreatic ductal adenocarcinoma (LM PDAC). Intra-individual CT and MRI examinations 112 patients with clinically proven LM PDAC were included. Four radiologists varying years (A > 20, B 5, C 1 D < 1) assessed segments affected by PDAC, as well associated occurring in each patient. Their sensitivity...
An 8-year-old intact male Shih Tzu dog was admitted with acute-onset tetraplegia. Magnetic resonance imaging showed an abnormality of the cervical intramedullary spinal cord. Histopathological examination a biopsy confirmed presence intravascular cartilaginous emboli. This is first report antemortem diagnosis fibrocartilaginous embolism in chondrodystrophoid breed dog.
Abstract The purpose of this study is to evaluate utility MRI in differentiation uterine low-grade endometrial stromal sarcoma (LGESS) from rare leiomyoma variants. This multi-center retrospective included consecutive 25 patients with LGESS and 42 variants who had pretreatment MRI. Two radiologists (R1/R2) independently evaluated features, which were analyzed statistically using Fisher’s exact test or Student's t -test. Subsequently, a five-point Likert scale, the two diagnostic performance...
This study aimed to establish an evaluation method for detecting uterine sarcoma with 100% sensitivity using MRI and serum LDH levels.One evaluator reviewed the images values of a total 1801 cases, including 36 cases 1765 fibroids. The reproducibility algorithm was also examined by four evaluators different imaging experience abilities, test set 61 14 sarcoma.From fibroids, we found that all sarcomas were included in group high T2WI either T1WI, unclear margin, or values. In addition, when...
Adenoid cystic carcinoma (ACC) is a relatively uncommon malignancy that most frequently arises in the salivary glands. In genital tract, approximately 60 cases of ACC originated from Bartholin glands have been reported to date. this report, we describe case arose Skene glands, very rare origin for disease. patient, disease had an indolent clinical course, with few symptoms other than localized pain. During surgical operation, tumor was found invaded more extensively estimated preoperatively,...
Frequent mutation of the ARID1A gene has been recently identified in ovarian clear-cell adenocarcinoma (CCA); however, clinical significance BAF250a expression encoded by remains to be determined. The aim present study was assess whether had an impact on features CCA. A total 97 cases CCA treated at a single institution were enrolled study. tissue samples evaluated immunohistochemical staining. BAF250a-deficient observed 30% (29/97) all cases. Of this, 19% non-atypical endometriosis, 26%...