- Gold and Silver Nanoparticles Synthesis and Applications
- Nanocluster Synthesis and Applications
- Boron Compounds in Chemistry
- Nanomaterials for catalytic reactions
- Immunotherapy and Immune Responses
- Nanotechnology research and applications
- Immune cells in cancer
- SARS-CoV-2 and COVID-19 Research
- Luminescence Properties of Advanced Materials
- Polymer Surface Interaction Studies
- Gas Sensing Nanomaterials and Sensors
- Monoclonal and Polyclonal Antibodies Research
- Catalytic Cross-Coupling Reactions
- Minerals Flotation and Separation Techniques
- RNA Interference and Gene Delivery
- CO2 Reduction Techniques and Catalysts
- Boron and Carbon Nanomaterials Research
- Advanced NMR Techniques and Applications
- Nuclear materials and radiation effects
- Radiation Effects and Dosimetry
- Click Chemistry and Applications
- Radiopharmaceutical Chemistry and Applications
- Immune Cell Function and Interaction
- Nanofabrication and Lithography Techniques
- Carbon dioxide utilization in catalysis
University of Milan
2020-2025
University of Helsinki
2020
Abstract Macrophages are crucial drivers of innate immunity. Reprogramming macrophages to a restorative phenotype in cancer or autoimmune diseases can stop their cancer‐promoting activity trigger anti‐inflammatory Glycans have emerged as key components for immunity they involved many pathophysiological disorders. Previous studies demonstrated that supraphysiological amounts mannose (Man) sialic acid (Sia) inhibit tumor growth and stimulate differentiation regulatory T cells. Man is known...
Boron neutron capture therapy (BNCT) for cancer is on the rise worldwide due to recent developments of in-hospital accelerators which are expected revolutionize patient treatments. There an urgent need improved boron delivery agents, and herein we have focused studying biochemical foundations upon a successful GLUT1-targeting strategy BNCT could be based. By combining synthesis molecular modeling with affinity cytotoxicity studies, unravel mechanisms behind considerable potential...
Ultra-small gold nanoparticles (UAuNPs) are extremely interesting for applications in nanomedicine thanks to their good stability, biocompatibility, long circulation time and efficient clearance pathways. UAuNPs engineered with glycans (Glyco-UAuNPs) emerged as excellent platforms many since the multiple copies of can mimic multivalent effect glycoside clusters. Herein, we unravel a straightforward photo-induced synthesis Glyco-UAuNPs based on reliable robust microfluidic approach. The...
Spherical polymer particles with alkyne functionalities were obtained by polymerisation induced self-assembly using Cu(0) mediated radical polymerisation. Mannosylation click reaction produced cyto-compatible lectin binding nanoparticles.
Abstract Ultra‐small gold nanoparticles (UAuNPs) are extremely interesting for applications in nanomedicine thanks to their good stability, biocompatibility, long circulation time and efficient clearance pathways. UAuNPs engineered with glycans (Glyco‐UAuNPs) emerged as excellent platforms many since the multiple copies of can mimic multivalent effect glycoside clusters. Herein, we unravel a straightforward photo‐induced synthesis Glyco‐UAuNPs based on reliable robust microfluidic approach....
Supramolecular ChemistryIn their Communication (e202215836), Ichiro Hisaki et al. demonstrate that cocrystallization of hexahydropyrene and pyrene derivatives yields porous frameworks composed non-stoichiometrically mixed multicomponent molecules through a hydrogen-bonded network.