- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Sulfur-Based Synthesis Techniques
- Venous Thromboembolism Diagnosis and Management
- Lipoproteins and Cardiovascular Health
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Urinary and Genital Oncology Studies
- Advanced MRI Techniques and Applications
- Bladder and Urothelial Cancer Treatments
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Organic and Inorganic Chemical Reactions
- Chemical Synthesis and Reactions
- Vascular Procedures and Complications
- Chemical Synthesis and Analysis
- Prostate Cancer Treatment and Research
- Synthesis and Catalytic Reactions
Iwate Medical University
2017-2025
Nippon Steel Yawata Memorial Hospital
2019-2023
Society for Vascular Surgery
2023
University of New Haven
2023
Japanese Circulation Society
2023
Columbia University Irving Medical Center
2018-2020
Robert Bosch (Germany)
2020
Cardiovascular Research Foundation
2018-2020
St. Francis Hospital
2019-2020
Fujita Animal Hospital
2020
Somatic stem cell (SC) therapy can improve cardiac performance following ischemic injury. In this study, we investigated whether induced pluripotent SC-derived cardiomyocytes (iPS-CMs) are more effective than somatic SCs, such as skeletal myoblasts (SM) and mesenchymal (M)SCs, in promoting functional recovery upon transplantation a porcine model of myocardial infarction.Myocardial injury was by ameroid ring placement immunosuppressed female mini pigs; after 1 month, epicardial performed with...
Receptor activator of NF-kappaB ligand (RANKL) and its receptor, receptor (RANK), play a key role in osteoclastogenesis, osteoprotegerin (OPG) acts as decoy for RANKL. We investigated the RANKL-RANK-OPG system renal cell carcinomas (RCCs), which frequently metastasize to bones. Real-time quantitative PCR revealed that RANKL mRNA expression was higher clear RCCs than papillary chromophobe RCCs. Similarly, protein level RCCs, showing positive correlations with primary tumour stage distant...
Vasohibin-1 (VASH1) is a novel angiogenic molecule that specifically expressed in activated vascular endothelial cells, and the status of VASH1 expression has been documented cancer angiogenesis. The aim this study was to address prognostic value upper urinary tract urothelial carcinomas (UTUC).We retrospectively analyzed clinical records 171 patients with locally advanced UTUC (Ta-3N0M0). median follow-up period 3.8 years. We immunohistochemically examined accomplished microvessels...
The geographical disparity in the pathophysiological pattern of coronary artery disease (CAD) among patients undergoing percutaneous intervention (PCI) is unknown.
Background: The safety and feasibility of using 1-month dual antiplatelet therapy (DAPT) followed by P2Y12inhibitor monotherapy for patients after percutaneous coronary intervention (PCI) with thin-strut biodegradable polymer drug-eluting stents (BP-DES) in daily clinical practice remain uncertain.
The clinical benefits of optical frequency domain imaging (OFDI)-guided percutaneous coronary intervention (PCI) for acute syndrome (ACS) remain unclear.
It has been reported that patients with acute myocardial infarction (AMI) transferred to low-volume primary percutaneous coronary intervention (PCI) hospitals (<115/year) in low population density areas experience higher in-hospital mortality rates. This study compared outcomes of admitted high-volume PCI (≥115/year) those for other regional general hospitals.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTunable regioselectivity associated with the reaction of 2,3-dihalo-1-(phenylsulfonyl)-1-propenes ambident nucleophilic reagentsAlbert Padwa, David J. Austin, Masaru Ishida, Cheryl L. Muller, S. Shaun Murphree, and Philip E. YeskeCite this: Org. Chem. 1992, 57, 4, 1161–1169Publication Date (Print):February 1, 1992Publication History Published online1 May 2002Published inissue 1 February...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic application of methyl(phenylthio)ketene. Synthesis vicinal-substituted cyclopentene derivativesMasaru Ishida, Toru Minami, and Toshio AgawaCite this: J. Org. Chem. 1979, 44, 13, 2067–2073Publication Date (Print):June 1, 1979Publication History Published online1 May 2002Published inissue 1 June 1979https://pubs.acs.org/doi/10.1021/jo01327a004https://doi.org/10.1021/jo01327a004research-articleACS PublicationsRequest reuse permissionsArticle...
Background:The efficacy and safety of ultrasound-guided thrombin injection (UGTI) for the treatment post-catheterization femoral brachial artery pseudoaneurysms (PSA) is unclear in Japan.Methods Results:A retrospective study 32 consecutive patients undergoing percutaneous UGTI PSA between February 2011 2014 was performed. There were 23 9 treated with UGTI. The prevalence CAD smoking history higher patients, but there no statistically significant differences other patient demographic factors...
Background: The association between symptom interpretation and prognosis has not been investigated well among patients with acute coronary syndrome (ACS). As such, the present study evaluated effect of heart disease awareness ACS on in-hospital mortality.
Abstract Background Statins are frequently administered to reduce low-density lipoprotein cholesterol (LDL-C) and vascular inflammation, because LDL-C high sensitive C-reactive protein (hs-CRP) associated with risk for cardiovascular events. When statins do not desired levels in high-risk patients coronary artery disease (CAD), ezetimibe can be added or the statin dose increased. However, which strategy is more effective treating CAD has been established. The present study compares...
Abstract Background The purpose of this study was to evaluate the prognostic value atrial fibrillation ( AF ) in patients with acute coronary syndrome ACS ). Methods A total 648 consecutive were divided into non‐ and all‐ groups. group further subdivided new‐onset pre‐existing We compared prognosis among these groups using Cox regression analysis. Results mean follow‐up period 1.4 ± 1.2 years. Overall patient numbers 538 110 (67 43 Seventy‐eight all‐cause deaths 42 cardiac observed....
Abstract In recent years, there have been several reports on robotic-assisted percutaneous coronary intervention (R-PCI), but few studies conducted R-PCI performed under intravascular imaging guidance. To elucidate the periprocedural and postoperative 30-day outcomes of imaging-guided R-PCI, we a retrospective observational study all patients in 102 consecutive cases who underwent guidance at single center Japan from June 12, 2019 to February 18, 2021. The primary end point was survival,...
This study evaluated the relationship between pre-PCI pathophysiological patterns of CAD assessed by QFR, intracoronary imaging findings, and their impact on immediate physiological outcomes after PCI in 206 patients.
Abstract Objectives We sought to assess plaque modification and stent expansion following orbital atherectomy (OA) for calcified lesions using optical coherence tomography (OCT). Background The efficacy of OA treating is not well studied, especially intravascular imaging in vivo. Methods OCT was performed preprocedure, post‐OA, post‐stent ( n = 58). Calcium after defined as a round, concave, polished calcium surface. fracture complete discontinuity calcium. Results Comparing pre‐ vs post‐OA...
Nutritional status has been reported to be a predictor of the outcomes critical limb ischemia. However, there have no reports association between nutritional and prognosis patients with intermittent claudication (IC). The aim this study was examine whether or not geriatric risk index (GNRI) is independently associated long-term elderly following open bypass for IC.