A5100610672- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Phytochemistry and Biological Activities
- Chromatography in Natural Products
- Ginseng Biological Effects and Applications
- Biological Activity of Diterpenoids and Biflavonoids
- Medicinal Plant Pharmacodynamics Research
- Pharmacological Effects of Natural Compounds
- Food Quality and Safety Studies
- Flavonoids in Medical Research
- Phytochemicals and Antioxidant Activities
- Heavy Metals in Plants
- Plant biochemistry and biosynthesis
- Botanical Studies and Applications
- Nephrotoxicity and Medicinal Plants
- Morinda citrifolia extract uses
- Chemical Synthesis and Analysis
- Food composition and properties
- Bioactive natural compounds
- Natural Compounds in Disease Treatment
- Tea Polyphenols and Effects
- Medicinal Plants and Neuroprotection
- Plant Physiology and Cultivation Studies
- Phytochemical compounds biological activities
- Hops Chemistry and Applications
ZheJiang Academy of Agricultural Sciences
2020
China Pharmaceutical University
2005-2016
Henan University
2007
Chinese Academy of Agricultural Sciences
2007
Abstract Introduction – The increasing demands of roots and rhizomes Salvia miltiorrhiza almost exhausted the wild sources in China. However, content composition phenolic acids aerial parts plant their potential to be used as a substitute has not been explored. Objective To evaluate new natural acids. Methodology HPLC coupled with diode array detection (DAD) electrospray ionization multistage mass spectrometry (ESI/MS n ) for qualitative quantitative analysis compounds. Results A total 38...
Background: Corosolic acid (CRA) is a pentacyclic triterpene that has been shown to exhibit an anti-atherosclerotic effect when added diets of low-density lipoprotein-deficient mice, but the mechanisms are unclear. The purpose present study was investigate molecular by which CRA ameliorates atherosclerosis. Methods and Results: anti-atherosclerosis in apolipoprotein E-deficient mice fed Western-type diet evaluated using atherosclerosis lesion area, serum profiles, gene expression...
Ginsenoside F 2 (F ), a protopanaxdiol type of saponin, was reported to inhibit human gastric cancer cells SGC7901. To better understand the molecular mechanisms , an iTRAQ‐based proteomics approach applied define protein expression profiles in SGC7901 response lower dose (20 μ M) and shorter duration (12 hour) treatment, compared with previous study. 205 proteins were screened terms change their level which met our predefined criteria. Further bioinformatics experiments demonstrated that...
ABSTRACT Introduction The whole herb of Potentilla discolor has long been used for treatment diarrhoea, malaria, haemoptysis and haematemesis in clinical applications. However, until now, there no literature regarding to the quality control it. Objective To develop a simple accurate HPLC‐DAD (diode array detection)–ESI/MS n (electrospray ionisation multistage mass spectrometry) method identification constituents P. simultaneous quantification its marker compounds. Methodology Separations...
AbstractThis article marks the first report on high-performance liquid chromatography (HPLC) coupled with diode-array detection (DAD) and quadruple time-of-flight mass spectrometry (Q-TOF/MS) for identification quantification of main bioactive constituents in Baeckea frutescens. In total, 24 compounds were identified or tentatively characterised based their retention behaviours, UV profiles MS fragment information. Furthermore, a validated method good linearity, sensitivity, precision,...
Abstract An analytical method based on high‐performance liquid chromatographic (HPLC) with ultraviolet (UV) detection was developed for determination of scopolin in rat plasma using aesculin as internal standard (IS). After protein precipitation sample methanol, the supernatant directly injected and analyzed. Chromatographic separation achieved a C 18 column methanol distilled water (22:78, v/v) containing 0.2% (v/v) glacial acetic acid mobile phase temperature 30°C. The UV detector set at...