A5101533431- Circadian rhythm and melatonin
- Photoreceptor and optogenetics research
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Olfactory and Sensory Function Studies
- Emotion and Mood Recognition
- Sleep and Wakefulness Research
- Receptor Mechanisms and Signaling
- Retinal Development and Disorders
- Pain Mechanisms and Treatments
- Behavioral Health and Interventions
- EEG and Brain-Computer Interfaces
- Mental Health Research Topics
- Adipose Tissue and Metabolism
- Visual perception and processing mechanisms
- Axon Guidance and Neuronal Signaling
- Neural and Behavioral Psychology Studies
- Color perception and design
- Tryptophan and brain disorders
- Optical Imaging and Spectroscopy Techniques
- Pain Management and Placebo Effect
- Speech Recognition and Synthesis
- Impact of Light on Environment and Health
- Zebrafish Biomedical Research Applications
- Child Abuse and Trauma
First Affiliated Hospital of Jinan University
2020-2025
Jinan University
2017-2025
Ningbo Kangning Hospital
2024
Ningbo University
2024
Northwestern University
2024
Second Xiangya Hospital of Central South University
2021
Central South University
2021
Nanjing Normal University
2017
Shanghai Mental Health Center
2017
Shanghai Jiao Tong University
2017
Our ex vivo and in studies demonstrate a molecular pathway for exercise-induced learning enhancement.
Exposure to addictive drugs triggers synaptic plasticity in reward-related brain regions, such as the midbrain, nucleus accumbens and prefrontal cortex. Effects of chronic drug exposure on other areas have not been fully investigated. Here, we characterize motor cortex after methamphetamine self-administration rats. We show that this causes a loss corticostriatal rat slices impaired learning rotarod task. These findings are paralleled by observation lack transcranial magnetic...
The lateral habenula (LHb) is implicated in emotional processing, especially depression. Recent studies indicate that the basal forebrain (BF) transmits reward or aversive signals to LHb. However, contribution of BF-LHb circuit pathophysiology depression still needs be determined. Here, we find excitatory projection LHb from substantia innominata (SI), a BF subregion, activated by stimuli and inhibited stimuli. Furthermore, chronic activation SI-LHb sufficient induce depressive-like...
<title>Abstract</title> In addition to its well-established role in vision, environmental light also plays a crucial non-image-forming visual functions, including the regulation of instinctive behaviors such as feeding. Clinical evidence suggests that bright therapy can alleviate symptoms individuals with obesity. However, neural mechanisms underlying influence on feeding remain poorly understood. this study, we demonstrate treatment effectively reduces food intake and mitigates weight gain...
Previous studies have shown that Lycium barbarum polysaccharide, the main active component of barbarum, exhibits anti-inflammatory and antioxidant effects in treating neurological diseases. However, therapeutic action polysaccharide on depression has not been studied. In this investigation, we established mouse models using aversive stimuli including exposure to fox urine, air puff foot shock physical restraint. Concurrently, administered 5 mg/kg per day polysaccharide-glycoprotein each...
Light in the environment greatly impacts a variety of brain functions, including sleep. Clinical evidence suggests that bright light treatment has beneficial effect on stress–related diseases. Although stress can alter sleep patterns, stress–induced alterations and underlying mechanism are poorly understood. Here, we show reduces increase nonrapid eye movement (NREM) induced by chronic through di–synaptic visual circuit consisting thalamic ventral lateral geniculate nucleus intergeniculate...
Abstract Research highlights the significance of increased bursting in lateral habenula (LHb) neurons depression and as a focal point for bright light treatment (BLT). However, precise spike patterns LHb projecting to different brain regions during depression, their roles development, BLT's therapeutic action remain elusive. Here, are found dorsal raphe nucleus (DRN), ventral tegmental area (VTA), median (MnR) exhibit following aversive stimuli exposure, correlating with distinct depressive...
In addition to its role in vision, light also serves non-image-forming visual functions. Despite clinical evidence suggesting the antipruritic effects of bright treatment, circuit mechanisms underlying on itch-related behaviors remain poorly understood. this study, we demonstrate that treatment reduces mice through a related lateral parabrachial nucleus (LPBN). Specifically, subset retinal ganglion cells (RGCs) innervates GABAergic neurons ventral geniculate and intergeniculate leaflet...
Nonsuicidal self-injury (NSSI) is a serious problem in the adolescent population worldwide. Childhood trauma and bullying have been identified as risk factors for NSSI. We explored relationships among trauma, Bullying victimization severity of NSSI behaviours, test effect mediating association between behaviours. A total 123 adolescents were recruited. They diagnosed with depression or depressive episodes bipolar disorder had experienced last year. assessed using Chinese version Trauma...
Affective computing draws more and attention to the human-computer interaction. Based on physiological signals acquired by body sensor network, within affection recognition process, problem that training samples have larger class distance smaller intraclass must be considered. For divisibility compactness problem, researching method of validity was proposed based metric multidimensional scaling. With dissimilarity matrix, scalar product matrix calculated. Subsequently, individual attribute...
The interaction of the affective has emerged in implicit human-computer interaction. Given physiological signals recognition process affective, different positions by which signal sensors are installed body, along with daily habits and moods human beings, influence signals. scalar product matrix was calculated this study based on metric multidimensional scaling dissimilarity matrix. Subsequently, individual attribute reconstructs obtained using principal component factor. method proposed...
Abstract Intermuscular fat (IMF), or muscular infiltration, has been inversely associated with measures of cognitive function. However, the mechanisms linking higher IMF and poor function are not fully understood. To explore this, we characterized plasma proteomic profile in Baltimore Longitudinal Study on Aging (BLSA, n=942), validated findings Coronary Artery Risk Development Young Adults (CARDIA; n=2453) study. Plasma proteomics was measured using 7K SOMAscan, CT scans thigh (BLSA)...
Abstract Background A motivation dimension of the core psychiatric symptom anhedonia additional has been suggested. The Temporal Experience Pleasure Scale (TEPS) reported to assess anticipatory and consummatory pleasure separately in multiple factor-structure models. This study explored factor structure a Chinese version 18-item TEPS further measurement invariance across sex clinical status (non-clinical, psychiatric). Methods Best-fit was examined non-clinical cohort 7410 undergraduates,...