A5032539183- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Radiomics and Machine Learning in Medical Imaging
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Ear and Head Tumors
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Tracheal and airway disorders
- Vascular Tumors and Angiosarcomas
- Dental Implant Techniques and Outcomes
- Viral-associated cancers and disorders
- Advanced Glycation End Products research
- Tannin, Tannase and Anticancer Activities
- Biological Activity of Diterpenoids and Biflavonoids
- Nitric Oxide and Endothelin Effects
- Lung Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Oral Health Pathology and Treatment
- Autophagy in Disease and Therapy
- Medical Imaging Techniques and Applications
- Esophageal Cancer Research and Treatment
- Histone Deacetylase Inhibitors Research
- Trauma Management and Diagnosis
- Genetics and Neurodevelopmental Disorders
Catholic University of Korea
2001-2021
Seoul St. Mary's Hospital
2020
Korea Institute of Radiological and Medical Sciences
2012
Hypoxia-inducible factor 1 alpha (HIF-1alpha), a component of HIF-1, is expressed in human tumors and renders cells able to survive grow under hypoxic (low-oxygen) conditions. YC-1, 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole, an agent developed for circulatory disorders that inhibits platelet aggregation vascular contraction, HIF-1 activity vitro. We tested whether YC-1 tumor growth vivo.Hep3B hepatoma, NCI-H87 stomach carcinoma, Caki-1 renal SiHa cervical SK-N-MC neuroblastoma were...
The reported incidence of tongue cancer in young patients has recently increased. aim this study was to analyze the clinical characteristics a group patients, and compare them with those an older patients.We retrospectively reviewed records 85 who were diagnosed squamous cell carcinoma tongue. They divided into two age groups: over 45 years under years. To prognosis similarly staged group, each early (stage I, II) advanced stage groups III, IV), then they compared. consisted 23 had 62...
Voice problems following thyroid surgery are well known, and perioperative voice analysis in patients undergoing thyroidectomy no longer seems optional. However, multiple means of assessing vocal function time-consuming, require specific instruments specialists, increase costs. Therefore, we designed this study to develop an efficient cost-effective screening tool for detecting disorders thyroidectomy.We developed the Perioperative Voice-Screening Protocol Thyroid Surgery (PVST) using...
<h3>BACKGROUND AND PURPOSE:</h3> Human papillomavirus is a prognostic marker for oropharyngeal squamous cell carcinoma. We aimed to determine the value of CT-based radiomics predicting human status and overall survival in patients with <h3>MATERIALS METHODS:</h3> Eighty-six carcinoma were retrospectively collected grouped into training (<i>n</i> = 61) test 25) sets. For prediction, features selected via random forest–based algorithm Cox regression analysis, respectively. Relevant used build...
Radiotherapy alone has several limitations for treating lung cancer. Inhalation, a non-invasive approach direct delivery of therapeutic agents to the lung, may help enhance efficacy radiation. Up-regulating beclin1, known as tumor suppressor gene that plays major role in autophagy, sensitize tumors and lead regression lungs K-rasLA1 cancer model mice. To minimize side-effects radiotherapy, fractionated exposures (five times, 24-h interval) with low dose (2 Gy) radiation restricted area...
Objectives. Head and neck squamous cell carcinomas (HNSCs) are frequently diagnosed at the locoregional advanced stage (stage IVa), but controversy remains regarding whether IVa HSNCs should be treated with upfront surgery or definitive chemoradiation therapy (CRT). The purpose of this study was to compare overall survival (OS) disease-free (DFS) in patients HNSC primarily by curative intent with/without (neo)adjuvant treatment (surgery group) versus those CRT (CRT group).Methods. We...
Conclusion: Median 18F-FDG PET/CT maximum standardized uptake values (SUVmax) cut-off of 7.9 or greater were associated with high-risk human papillomavirus (HPV) negativity in patients hypopharyngeal squamous cell carcinoma (HPSCC). Furthermore, median SUVmax and HPV adverse outcomes. Objectives: We studied the association potential prognostic significance status HPSCC. Methods: The medical records 45 who underwent for HPSCC before surgery reviewed. High-risk situ hybridization was performed...
Smooth muscle relaxation induced by various agents that increase the cellular levels of cyclic nucleotides (cAMP and cGMP) is accompanied a decrease in intracellular Ca2+ concentration. However, little known about differences between inhibitory effects cAMP cGMP on contraction smooth muscle.To compare underlying mechanisms inhibition gastric contraction, nucleotide promoting agents, as well cell membrane permeable were used.Isometric was measured from circular strips prepared fundus cat...
Background and ObjectivesZZThe aim of this study was to evaluate the incidence prognostic significance cervical lymph node metastasis in squamous cell carcinoma (SCC) hypopharynx.Subjects MethodZZA retrospective review 64 patients who were previously untreated for SCC hypopharynx underwent surgery performed from October 1993 June 2008.Fifty-six had simultaneous bilateral neck dissection, whereas eight unilateral dissection.ResultsZZThe median age 61.0 years (range, 34-75 years) group...