A5000156589- Potato Plant Research
- Plant Pathogens and Resistance
- Mesenchymal stem cell research
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Tissue Engineering and Regenerative Medicine
- Plant Disease Resistance and Genetics
- Genomics and Phylogenetic Studies
- Microbial infections and disease research
- Innovations in Medical Education
- Molecular Biology Techniques and Applications
- Problem and Project Based Learning
- Ocular Surface and Contact Lens
- Powdery Mildew Fungal Diseases
- Plant-Microbe Interactions and Immunity
- RNA and protein synthesis mechanisms
- COVID-19 and healthcare impacts
- Bacteriophages and microbial interactions
- Electrospun Nanofibers in Biomedical Applications
- Plant Pathogens and Fungal Diseases
- Education and Critical Thinking Development
- Gene expression and cancer classification
- Adipose Tissue and Metabolism
- COVID-19 and Mental Health
- Yeasts and Rust Fungi Studies
Aalborg University
2012-2023
Aalborg University Hospital
2020
StemCells (United States)
2018
Institute for Biomedicine
2010-2015
Aarhus University
1998
University of Copenhagen
1972
Powdery mildew and rust fungi are widespread, serious pathogens that depend on developing haustoria in the living plant cells. Haustoria separated from host cytoplasm by a cell-derived extrahaustorial membrane. They secrete effector proteins, some of which subsequently transferred across this membrane to cell suppress defense.In cDNA library barley epidermis containing powdery haustoria, two-thirds sequenced ESTs were fungal represented approximately 3,000 genes. Many most highly expressed...
Digital transcriptomics with pyrophosphatase based ultra-high throughput DNA sequencing of di-tags provides high sensitivity and cost-effective gene expression profiling. Sample preparation handling are greatly simplified compared to Serial Analysis Gene Expression (SAGE). We compare DeepSAGE LongSAGE data demonstrate greater power detection multiplexing samples derived from potato. The transcript analysis revealed a great abundance up-regulated potato transcripts associated stress in...
Abstract Background Adipose-derived stem cells (ASCs) are being increasingly recognized for their potential to promote tissue regeneration and wound healing. These effects appear be partly mediated by paracrine signaling pathways, enhanced during hypoxia. Mass spectrometry (MS) is a valuable tool proteomic profiling of cultured ASCs, which may help reveal the identity factors secreted under different conditions. However, serum starvation essentially required obtain samples compatible with...
Objective To identify what motivates medical students to join a pandemic emergency healthcare workforce. Design Cross-sectional study. Setting Aalborg University, Denmark. Participants All students. Main outcome measures Motivational points as perceived by the be important. Demographic characteristics and 11 motivational domains scored on Visual Analog Scale from 0 (low) 100 (high) responding question: ‘To degree are following statements important for you national preparedness workforce?’...
The aim of this study was to assess whether Escherichia coli phylogenetic groups were associated with the site infection and level antibiotic resistance in community-acquired bacteraemia (CAB).The population-based cohort included 1533 unique isolates E. from Danish patients CAB during a 10 year period. Triplex PCR used classify groups, susceptibility testing performed by disc diffusion. Data analysed using contingency tables logistic regression.Overall, 65.9% belonged phylogroup B2, 16.6% D,...
The major potato tuber proteins of the Kuras cultivar, which is dominant cultivar used in Northern Europe for industrial starch production, were analysed using 1D and 2D gel electrophoresis. electrophoretic patterns varied significantly depending on method preparation variant ( Solanum tuberosum ). Proteins characterized MS scored against protein databases, derived from both ‘Kuras only’ ‘all potato’ expressed sequence tags (EST) full‐length cDNAs. Despite existence ∼ 180 000 ESTs, currently...
Corneal epithelium is maintained throughout life by well-orchestrated proliferation of limbal epithelial stem cells (LESCs), followed migration and maturation centripetally towards the ocular surface. Disturbance LESCs can potentially lead to a blinding condition, which be reversed reconstitution functional LESC pool. The current clinical procedures are effective some degree, however, deeper knowledge molecular interplay within niche necessary achieve fully satisfactory patient outcome....
This is the first report of biosynthetic potential a tuber storage organ investigated by expressed sequence tag sequencing. A cDNA library was generated from mature field grown potato ( Solanum tuberosum var. Kuras). Partial sequences obtained 6077 clones were assembled into 828 clusters and 1533 singletons. The average read length 592 bp, 2254 full length. 5717 showed homology to genes other organisms. Genes involved in protein synthesis, destination cell defense predominated compared...
The purpose of this study was to explore the relationship problem-based learning (PBL) and development critical thinking disposition (CT) academic achievement in Chinese medical students using a cross-sectional randomized design. Medical from China University (CMU) were PBL or non-PBL teaching at commencement study. After five years study, CT scored by version California Critical Thinking Disposition Inventory (CCTDI-CV). score achieved on Computer Case Simulation (CCS) test evaluated...
Ex vivo cultured human limbal epithelial stem/progenitor cells (hLESCs) are the main source for regenerative therapy of stem cell deficiency (LSCD), which is worldwide one major causes corneal blindness. Despite many stemness-associated markers have been identified within niche, phenotype earliest hLESCs has not hitherto identified. We sought to confirm or refute use tumor protein p63 (p63) and ATP binding cassette subfamily B member 5 (ABCB5) as surrogate early differentiation hierarchy....
Solanum tuberosum (potato) is the fourth major crop worldwide and used for food, feed biotechnological applications. To fully realize biosynthetic potential production of starch, protein metabolites, we conducted an extensive quantitative profiling expressed genes mature potato tuber. A total 58,322 serial analysis gene expression (SAGE) tags 19 nucleotides (nt), representing 22,233 different tags, were analysed. The 695 seen 10 or more times assigned a tentative function by comparison with...
Smooth muscle differentiated adipose tissue-derived stem cells are a valuable resource for regeneration of gastrointestinal tissues, such as the gut and sphincters. Hypoxia has been shown to promote proliferation maintenance pluripotency, but influence hypoxia on their smooth myogenic differentiation remains unexplored. This study investigated phenotype contractility adipose-derived toward lineage under hypoxic conditions. Oxygen concentrations 2%, 5%, 10%, 20% were used during cells. Real...