A5089383750- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Metabolism, Diabetes, and Cancer
- Cardiovascular Function and Risk Factors
- Diabetes Treatment and Management
- Additive Manufacturing Materials and Processes
- High Entropy Alloys Studies
- Vascular Tumors and Angiosarcomas
- Sarcoma Diagnosis and Treatment
- Cardiac tumors and thrombi
- Atrial Fibrillation Management and Outcomes
- Erythropoietin and Anemia Treatment
- Peptidase Inhibition and Analysis
- Lipoproteins and Cardiovascular Health
- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Chemokine receptors and signaling
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Corporate Taxation and Avoidance
- Coronary Interventions and Diagnostics
- Soft Robotics and Applications
- Cardiac Imaging and Diagnostics
Juntendo University
2021-2025
Tohoku University
2016
Waseda University
2014
Abstract Background The nutritional status and frailty are crucial in patients with aortic stenosis (AS) undergoing transcatheter valve implantation (TAVI), as they significantly impact outcomes. We have previously developed an easily calculable index, TCBI (Triglycerides, total Cholesterol, Body weight Index), which has been validated a prognostic indicator various cardiovascular disease contexts. This study aimed to evaluate the of low on outcomes TAVI. Methods is part Japanese...
Abstract Dipeptidyl-peptidase-4 inhibitors (DPP4i) have been the most used antidiabetic medications worldwide due to their good safety profiles and tolerability with a low risk of hypoglycemia, however, large cardiovascular outcome trials (CVOTs) not shown any significant prognostic superiority. On contrary, since observational studies suggested effects DPP4i are enhanced some populations, such as Asians those who without overweight, benefit is still under debate. The aim this study was thus...
Central venous catheterization is associated with potential complications secondary to accidental puncture, including bleeding and pneumothorax. We developed a system that avoids these simplifies the procedure using robot provide puncture assistance. herein report experiment conducted in vivo porcine evaluate manipulator. The right left jugular veins of pig were punctured five times each through both opened unopened skin at angle speed. A placement rate 80% was obtained skin. much lower 40%...
Pulmonary hypertension (PH) is a common complication of aortic stenosis (AS). Despite the established association between PH and poor outcomes in patients with AS, prognostic implication change after transcatheter valve implantation (TAVI) has been rarely evaluated. This study analyzed prospective multi-center TAVI registry database involving six Japanese centers used transtricuspid pressure gradient (TRPG) obtained by echocardiography to estimate pulmonary artery systolic pressure. The...
Pulmonary artery sarcoma is a rare malignant neoplasm arising from intimal mesenchymal cells in the pulmonary wall and often difficult to differentiate embolism, however, 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) can be useful for differential diagnosis. Here, we present case of undetectable by PET.A 77-year-old woman who had worsening dyspnoea on effort month progressive chest discomfort with nocturnal cough week presented our hospital. Contrast-enhanced computed (CT)...
Little is known about the long-term outcomes of β-blockers use in patients with coronary artery disease (CAD) without myocardial infarction (MI) and reduced ejection fraction (rEF). However, more attention should be paid to oral administration elderly who are susceptible heart failure (HF), sinus node dysfunction, or rate response insufficiency. We aimed evaluate impact CAD MI systolic HF have undergone percutaneous intervention.A total 1018 consecutive (mean age, 72 ± 7 years; 77% men)...
Atypical Shone's complex is a rare congenital anomaly involving left-sided obstructive lesion of two or three cardiovascular levels. A 70-year-old man with dyspnea on exertion was diagnosed severe aortic stenosis (AS) bicuspid valve, complicated by coarctation (CoA) and double-orifice mitral valve. He underwent surgery for AS CoA in one session. It important to search malformations, even cases valve found old age.
Abstract Purpose Asians often face the problems of clopidogrel resistance and East Asian paradox. This study aimed to evaluate effects P2Y12 inhibitors, including low-dose prasugrel 2.5 mg, on reaction unit (PRU) in chronic phase after percutaneous coronary intervention (PCI). Methods A total 348 patients were studied. PRU was measured 6-12 months PCI subsequently, 6 later using a assay, respectively. evaluated proportion bleeding risk (PRU ≤85) ischemic ≥239) as primary endpoints,...
Abstract Background: Dipeptidyl-peptidase-4 inhibitors (DPP4i) have become one of the most used antidiabetic medications worldwide due to their good safety profiles and tolerability with a low risk hypoglycemia, however, no large cardiovascular outcome trials (CVOTs) shown any significant superiority respect reducing risk. On contrary, since observational studies suggested effects DPP4i are enhanced some populations, such as Asians those who without overweight, prognostic benefit is still...
Introduction: The evidence-based optimal medical therapy has been encouraged in the treatment of patients with coronary artery disease. However, as follow-up periods are limited (-5 years) most randomized trials, prognostic efficacy drugs longer time period not fully evaluated. Therefore, this registry-based study aimed to simultaneously address long-term impact 6 major classes cardiovascular (CV) drugs, beta-blockers (BBs), calcium channel blockers (CCBs), angiotensin converting enzyme...
Background: Anemia is one of the most common complications chronic kidney disease (CKD), renal anemia, which has a significant link with increased risk morbidity, as well mortality cardiovascular disease. However, prognostic implication temporal change anemia status been rarely addressed, especially in secondary prevention coronary artery (CAD). Methods and Results: This long-term (median follow-up range: 5.7 years) single center observational study involved consecutive 416 patients CKD over...