A5061734930- Trypanosoma species research and implications
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Vector-borne infectious diseases
- Zoonotic diseases and public health
- Viral Infections and Vectors
- Parasites and Host Interactions
- Mosquito-borne diseases and control
- Brucella: diagnosis, epidemiology, treatment
- Dermatological diseases and infestations
- Rabies epidemiology and control
- Research on Leishmaniasis Studies
- Insect symbiosis and bacterial influences
- Parasitic Diseases Research and Treatment
- Agricultural Innovations and Practices
- Congenital Anomalies and Fetal Surgery
- Parasitic infections in humans and animals
- Helminth infection and control
- Viral gastroenteritis research and epidemiology
- HIV/AIDS drug development and treatment
- Virology and Viral Diseases
- Burkholderia infections and melioidosis
- Cytomegalovirus and herpesvirus research
- Prion Diseases and Protein Misfolding
- Ecology and Vegetation Dynamics Studies
Makerere University
2014-2025
Coordinating Office for Control of Trypanosomiasis in Uganda
2014-2022
Lincoln University
2022
International Livestock Research Institute
2022
University of Pretoria
2022
Purdue University System
2022
Ministry of Agriculture, Animal Industry and Fisheries
2021-2022
Charles Sturt University
2022
University of Edinburgh
2021
Freie Universität Berlin
1999
Human brucellosis has been found to be prevalent in the urban areas of Kampala, capital city Uganda. A cross-sectional study was designed generate precise information on prevalence cattle and risk factors for disease its peri-urban dairy farming systems. The adjusted herd 6.5% (11/177, 95% CI: 3.6%-10.0%) individual animal 5.0% (21/423, 2.7% - 9.3%) based diagnosis using commercial kits competitive enzyme-linked immunosorbent assay (CELISA) Brucella abortus antibodies. Mean within-herd 25.9%...
Abstract Background The northwards spread of acute T. b. rhodesiense sleeping sickness in Uganda has been linked to cattle movements associated with restocking following the end military conflict 2006. This study examined number traded from T . b endemic districts, prevalence parasite being and level trypanocidal treatment at livestock markets. Methods Between 2008 2009 interviews were carried out government veterinarians 20 districts Uganda, 18 organisations numerous traders veterinarians....
Sleeping sickness, or Human African Trypanosomiasis (HAT), is caused by two distinct parasites. In East and Southern Africa, Trypanosoma brucei rhodesiense causes the Rhodesian form of disease (about 2% all reported cases [1]). Central West T. b. gambiense Gambian (G-HAT—about 98% The normally affects remote rural communities. people most at risk are those working outdoors for long periods, as they exposed to bite tsetse fly (Glossina spp.: Diptera), which transmits comparable diseases occur...
A retrospective case–control study of human brucellosis in urban, peri‐urban, and rural areas Kampala, Uganda was undertaken to find the risks associated with disease using medical records Mulago National Referral Hospital (Mulago Hospital). From Brucella agglutination test (BAT) between June 2004 May 2006, 652 positive results were found. The showed that living urban a risk factor for brucellosis. numbers improved cross‐breed cattle per 1000 households calculated on basis data obtained from...
Tick-borne diseases (TBDs) present a major economic burden to communities across East Africa. Farmers in Africa must use acaracides target ticks and prevent transmission of tick-borne such as anaplasmosis, babesiosis, cowdriosis theileriosis; the causes cattle mortality morbidity. The costs controlling Coast Fever (ECF), caused by Theileria parva, Uganda are significant measures taken control ticks, be cost-effective, should take into account disease. aim work was estimate presented T. parva...
Abstract Background Caused by trypanosomes and transmitted tsetse flies, Human African Trypanosomiasis bovine trypanosomiasis remain endemic across much of rural Uganda where the major reservoir acute human infection is cattle. Following elimination mass trypanocidal treatment, it crucial that farmers regularly apply pyrethroid-based insecticides to cattle sustain parasite reductions, which also protect against tick-borne diseases. The private veterinary market divided between products only...
Background Animal tungiasis is believed to increase the prevalence and parasite burden in humans. reservoirs of Tunga penetrans differ among endemic areas their role epidemiology had never been investigated Uganda. Methods Findings To identify major animal relative importance transmission Uganda, a cross sectional study was conducted rearing households 10 villages Bugiri District. T. infections were detected pigs, dogs, goats cat. The prevalences with ranged from 0% 71.4% (median 22.2) for...
Tsetse-transmitted African trypanosomes cause both nagana (African animal Trypanosomiasis-AAT) and sleeping sickness (human Trypanosomiasis - HAT) across Sub-Saharan Africa. Vector control chemotherapy are the contemporary methods of tsetse trypanosomiasis in this region. In most countries, including Uganda, veterinary services have been decentralised privatised. As a result, livestock keepers meet costs these services. To be sustainable, AAT programs need to tailor inelastic budgets...
Gambiense human African trypanosomiasis (g-HAT) is the chronic form of sleeping sickness caused by Trypanosoma brucei gambiense in West and Central Africa, while rhodesiense causes an acute eastern Africa. g-HAT targeted for elimination as a public health problem 2020 0 transmission 2030 [1,2]. Control largely based on identification treatment infected individuals, supplemented control tsetse fly vectors [3]. There has been growing evidence that when both case activities are carried out...
Abstract Background Tungiasis is a neglected tropical disease which common in impoverished communities. In sub-Saharan Africa, it caused by female sand fleas, Tunga penetrans , and pigs are amongst the major domestic animal reservoirs. Depending on environment, tungiasis occurs throughout year or preferentially dry seasons. This study investigated changes flea abundance associated morbidity during season. Methods lesions were counted staged 35 22 households with at least one affected pig....
The persistence of sleeping sickness (human African trypanosomiasis) in some areas south-eastern Uganda has necessitated further investigations, focusing mainly on domestic animals as reservoirs this disease three agro-ecological zones. inter-zone differences the prevalences trypanosome infection among cattle (P < 0.001) and pigs were significant. Overall, 5.0% cattle, 13.9% 0.4% small ruminants investigated found to be infected with parasites Trypanosoma brucei subgroup.The results blood...
Background In Kampala, Uganda, studies have shown a significant incidence of human brucellosis. A stochastic risk assessment involving two field surveys (cattle farms and milk shops) medical record survey was conducted to assess the brucellosis infection through consumption informally marketed raw potentially infected with Brucella abortus in Kampala identify best control options. Methodology/Principal Findings cattle farm survey, sera 425 cows 177 herds economic zone were sampled tested for...
Background African trypanosomes constrain livestock and human health in Sub-Saharan Africa, aggravate poverty hunger of these otherwise largely livestock-keeping communities. To solve this, there is need to develop use effective cheap tsetse control methods. this end, we aimed at determining the smallest proportion a cattle herd that needs be sprayed on legs, bellies ears (RAP) for Human Animal Trypanosomiasis (HAT/AAT) control. Methodology/Principal finding Cattle 20 villages were...
African animal trypanosomiasis (AAT) is considered to be one of the greatest constraints livestock production and livestock-crop integration in most countries. South-eastern Uganda has suffered for more than two decades from outbreaks zoonotic Human Trypanosomiasis (HAT), adding burden faced by communities AAT. There insufficient AAT HAT data available (in reservoir) guide prioritize control programs that been generated using contemporary, sensitive specific molecular techniques. This study...
Brucellosis is a key zoonosis of major public health, animal welfare and economic significance, endemic in livestock Uganda. A cross-sectional epidemiological study was carried out to estimate the sero-prevalence brucellosis identify factors associated with sero-positivity cattle urban peri-urban Gulu Soroti towns Northern Eastern Uganda, respectively. total 1007 sera data on biologically plausible risk from 166 herds their spatial locations, were collected reared The analyzed using indirect...
Brucellosis is endemic in livestock and humans Uganda its transmission involves a multitude of risk factors like consumption milk from infected cattle. To shed new light on the epidemiology brucellosis present study used phenotypic molecular approaches to delineate Brucella species, biovars, genotypes cattle milk. abortus without biovar designation was isolated eleven out 207 samples Uganda. These isolates had genomic monomorphism at 16 variable number tandem repeat (VNTR) loci showed turn...
The recent recognition of neurocysticercosis as a major cause epilepsy in Uganda and changes pig demography have lead to need better understand the basic epidemiology Taenia solium infections pigs humans. Human exposure is function size animal reservoir this zoonosis. This first field survey for porcine cysticercosis investigate prevalence antigen-positive across an entire rural district south-east Uganda. In our surveys, 8.6% 480 screened were seropositive parasite by B158/B60 Ag-ELISA....
A study was conducted in Tororo District eastern Uganda to assess the socio-economic contribution of draft cattle rural livelihoods. The aim empirically quantify economic value thus contributing understanding impact endemic parasitic diseases on livestock productivity and subsequently household income, labor food security. total 205 keeping households (n = 205) were randomly selected structured questionnaires administered, focusing work oxen use, productivity, inputs outputs. data obtained...
Uganda has suffered from a series of epidemics Human African Trypanosomiasis (HAT), tsetse transmitted disease, also known as sleeping sickness. The area affected by acute Trypanosoma brucei rhodesiense HAT (rHAT) been expanding, driven importation infected cattle into regions previously free the disease. These are Animal (AAT) demanding strategy for integrated disease control. In 2008, Public Private Partnership, Stamp Out Sleeping Sickness (SOS) administered single dose trypanocide to 31...
Tunga penetrans (Insecta, Siphonaptera, Tungidae) causes severe morbidity among heavily infected humans and animals in Latin America sub-Saharan Africa. The clinical pathology of tungiasis has never been studied systematically. This was a cross-sectional study conducted between January to March 2015, aimed at describing tungiasis-associated 121 20 T. penetrans-infected pigs dogs, living nine five endemic rural villages respectively located Bugiri District, Busoga, Uganda. parasite load...