A5101972830- Tuberculosis Research and Epidemiology
- Cervical Cancer and HPV Research
- Infectious Diseases and Tuberculosis
- Genital Health and Disease
- Diagnosis and treatment of tuberculosis
- Colorectal and Anal Carcinomas
- Pneumocystis jirovecii pneumonia detection and treatment
- Immune responses and vaccinations
- Hepatitis B Virus Studies
- Reproductive tract infections research
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Tea Polyphenols and Effects
- Radical Photochemical Reactions
- Drug Transport and Resistance Mechanisms
- Tracheal and airway disorders
- Transplantation: Methods and Outcomes
- Mycobacterium research and diagnosis
- Orthopedic Infections and Treatments
- Cancer-related molecular mechanisms research
- Head and Neck Cancer Studies
- Catalytic C–H Functionalization Methods
- Pneumonia and Respiratory Infections
- Bone fractures and treatments
- Organ Transplantation Techniques and Outcomes
Wuhan University
2023-2024
EarthTech International (United States)
2024
Second Affiliated Hospital of Chongqing Medical University
2023
Dalian Medical University
2023
Chongqing Medical University
2023
Sun Yat-sen University
2023
Fifth Affiliated Hospital of Sun Yat-sen University
2023
Hubei University of Medicine
2021-2022
Nanjing University of Chinese Medicine
2021-2022
The People's Hospital of Guangxi Zhuang Autonomous Region
2012-2021
In light of China's unique ethnic and sociocultural context, a marked rise in HIV prevalence among MSM, it is important to determine prevalence, genotypes predictors anal human papillomavirus (HPV) HIV-infected uninfected men who have sex with (MSM) Beijing, China.In 2010-2011, we recruited MSM (age range 18-61; median 28 years) through peer volunteers, collected demographic/behavioral information via interviewer-administrated questionnaires. Trained health workers swabs for HPV genotyping...
Abstract Anal human papillomavirus (HPV) infection, which is linked to anal warts and cancer, common among men who have sex with (MSM), especially those HIV positives. MSM aged 18 years or older were recruited from mainland China. Blood cytologic samples collected for HIV-1 serological test HPV genotyping. A total of 889 eligible participations included. The genotyping results available 822 participants (92.46%), 65.32% positive the targeted 37 types. Prevalence infection any type was higher...
Latent tuberculosis infection (LTBI) management is now a critical component of the World Health Organization's End TB Strategy.In this randomised controlled trial (Chinese Clinical Trial Registry identifier ChiCTR-IOR-15007202), two short-course regimens with rifapentine plus isoniazid (a 3-month once-weekly regimen and 2-month twice-weekly regimen) were initially designed to be evaluated for rural residents aged 50-69 years LTBI in China.Due increasingly rapid growth unexpected high...
Objective: Corticosteroid injection is a common treatment for primary frozen shoulder, but controversy remains regarding whether different approaches to the glenohumeral joint have similar clinical benefits.Design: Randomized controlled trial.Patients: A total of 60 patients with shoulder were divided randomly into either anterior or posterior approach groups.Methods: Both groups received 5-mL drug injection, including 1 mL 40 mg/mL triamcinolone acetonide and 4 2% lidocaine. Follow-up...
Background Anal HPV infection, which contributes to the development of anal warts and cancer, is well known be common among men who have sex with (MSM), especially those HIV positives. However, co-infection MSM has not been addressed in China. Methods A cross-sectional study was conducted Beijing Tianjin, Study participants were recruited using multiple methods collaboration local volunteer organizations. Blood swabs collected for HIV-1 serological test genotyping. Results total 602...
Prospective population data on the incidence of tuberculosis (TB) infection has been sparsely reported in global literature.A population-based prospective study was conducted rural China to investigate annual risk TB infection, and its persistence using serial tuberculin skin tests (TSTs) an interferon-γ release assay. In total, 13 580 eligible participants from four sites, identified as TST negative (<10 mm) or QuantiFERON-TB Gold In-Tube (QFT) (an assay) a baseline survey, were included...
Abstract Body mass index (BMI) has been shown to be associated with host susceptibility several infections. However, the link between BMI and risk of tuberculosis (TB) infection sparsely studied in China worldwide. Based on baseline survey a population-based, prospective study rural China, association TB among adults was estimated by means cross-sectional analysis. status tested using QuantiFERON-TB Gold In-Tube (QFT), commercial interferon-γ release assay (IGRA). Totally, 17796 eligible...
Objectives China has high burden on both of tuberculosis (TB) and tobacco use. This study aims to explore the potential link between smoking TB infection using baseline survey data a large-scale population-based prospective in rural Methods Between July 1 Sept 30, 2013, based population-based, China, relationship infection, assessed by interferon-gamma release assays (IGRA), was investigated among total population only those smokers, respectively. Results A 21,008 eligible registered...
Objective To determine the impact factors of latent tuberculosis infection (LTBI) and knowledge TB prevention treatment policy among health care workers (HCWs) in different types hospitals explore strategies for improving control medical institutions China. Methods A cross-sectional study was carried out to evaluate risk personnel occupational protection HCWs who directly engage duties one two public hospitals. Each potential participant completed a structured questionnaire performed...
Association studies have been employed to investigate the relationships between host single nucleotide polymorphisms (SNPs) and susceptibility pulmonary Tuberculosis (PTB). However, such candidate genetic markers not widely studied in Chinese population, especially with respect disease development from latent M. tuberculosis infection (LTBI).In this case-control study, 44 SNPs were examined a total of 600 participants (PTB patients, LTBI controls healthy without infection) Zhengzhou, China....
Abstract During China’s urbanization process, rural labor migrants have been suggested to be one important bridge population change urban-rural distribution on tuberculosis (TB) burden. Aiming estimate the prevalence of TB infection and track active disease development in migrants, a prospective study was conducted Shenzhen city, southern China. detected using interferon-γ release assay (IGRA). Here we mainly report characteristics based baseline survey. A total 4,422 eligible participants...
Simvastatin is considered as a stimulator for bone formation. However, the half-life simvastatin generally 2 hours, which means, it difficult to maintain biologically active in vivo. To overcome this limitation, we created system slowly release vitro and We constructed poly(lactic-co-glycolic acid)/hydroxyapatite nano-fibrous scaffold carry simvastatin. Releasing assays showed that was released from acid)/hydroxyapatite/simvastatin quickly within - 15 days, small amounts continued be through...
Background Men who have sex with men (MSM) were found to be one of the high-risk populations for Entamoeba histolytica (E. histolytica) infection. Accompanied by prevalence human immunodeficiency virus (HIV) among MSM, invasive amebiasis caused E. has been paid attention as an opportunistic parasitic However, status infection MSM barely studied in mainland China. Methods Seroprevalance was determined using enzyme-linked immunosorbent assay based on a cross-sectional study conducted Beijing...
Abstract High mobility group A2 (HMGA2) is an architectural transcription factor that promotes human colorectal cancer (CRC) aggressiveness by modulating the of target genes. The degradation p53 mediated murine double minute 2 (MDM2) in a proteasome‐dependent manner. Here we report HMGA2 cell cycle progression and inhibits apoptosis CRC cells vitro . We also developed intestinal epithelial cell‐specific Hmga2 knock‐in (KI) mouse model. It revealed KI promoted chemical carcinogen‐induced...
Background In the recent years, dramatic increases in HIV transmission among men who have sex with (MSM) been observed China. Human papillomavirus (HPV) infection related anal cancer is more common HIV-infected MSM as compared to general population. However, HPV and cytology has rarely studied Methods Beijing, China were invited participate this study between January April 2011. Anal swabs collected for examining genotypes. Results Ninety-five eligible participants complete questionnaire...
Background Anal human papillomavirus (HPV) infection and its related diseases are relatively common in men who have sex with (MSM), especially those HIV positive. In China, molecular epidemiology of anal HPV among HIV-positive MSM has been sparsely studied. Methods A cross-sectional study was conducted Xi'an, China between April July 2014. swabs were collected for genotyping. Results total 195 included this study. genotyping showed that 99.0% (191/193) participants positive at least one the...