Jinsheng Xu

ORCID: 0000-0001-6453-1853
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About
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Research Areas
  • Parathyroid Disorders and Treatments
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Magnetism in coordination complexes
  • Metal-Organic Frameworks: Synthesis and Applications
  • Electrochemical sensors and biosensors
  • Liver physiology and pathology
  • Metal complexes synthesis and properties
  • Analytical Chemistry and Sensors
  • Magnesium in Health and Disease
  • 3D Printing in Biomedical Research
  • Electrochemical Analysis and Applications
  • Oral health in cancer treatment
  • Radioactive element chemistry and processing
  • Neuroscience and Neuropharmacology Research
  • Crystallography and molecular interactions
  • Dialysis and Renal Disease Management
  • Caveolin-1 and cellular processes
  • Drug-Induced Hepatotoxicity and Protection
  • Animal testing and alternatives
  • Medical Imaging and Pathology Studies
  • Pharmacogenetics and Drug Metabolism
  • Lanthanide and Transition Metal Complexes
  • Aortic aneurysm repair treatments
  • Crystal structures of chemical compounds

High Magnetic Field Laboratory
2024

Chinese Academy of Sciences
2024

Anhui University
2024

Hebei Medical University
2012-2021

Fourth Hospital of Hebei Medical University
2013-2021

Xinxiang Central Hospital
2018

The Sixth People's Hospital of Zhengzhou
2015

University of the West of England
1999-2014

Hengyang Normal University
2007-2014

Henan Provincial People's Hospital
2013

Abstract Three‐dimensional culture systems are an ideal in vitro model being capable of sustaining cell functionalities a manner that resembles the vivo conditions. In present study, we developed ultrasound trap‐based technique to rapidly produce HepG2 hepatocarcinoma aggregates within 30 min. Enhanced junctional F‐actin was observed at points cell–cell contact throughout aggregates. prepared by trap can be maintained on P‐HEMA‐coated surface for up 3 weeks. The cells these proliferated...

10.1002/jcb.21345 article EN Journal of Cellular Biochemistry 2007-04-17

Coconut husk activated carbon (CHAC) was used as an adsorbent to remove hexavalent uranium (U(VI)) from aqueous solutions by adsorption. Batch experiments were conducted investigate the effects of contact time, pH, initial U(VI) concentration, and dosage on The adsorption process reached equilibrium state after 150 min. uptake highly pH dependent, optimum at near-neutral pH. High removal efficiencies could be achieved increasing CHAC dosages. capacity increased with concentrations. Above a...

10.1080/19443994.2014.977956 article EN Desalination and Water Treatment 2014-11-10

Vascular calcification (VC), in which high serum phosphate plays a critical role, is one major problem patients with chronic kidney disease. Clinical studies report that magnesium has protective effect on VC. However, the regarding impact of VC at cellular level are few and require further investigation. Therefore, present study explored induced by β-glycerophosphate (BGP) rat aortic vascular smooth muscle cells (RAVSMCs). In study, addition decreased calcium deposition, was increased BGP....

10.3892/br.2015.473 article EN Biomedical Reports 2015-05-27

This report describes the design and development of an integrated electrochemical cell culture monitoring system, based on enzyme-biosensors chemical sensors, for indicators mammalian metabolic status. MEMS technology was used to fabricate a microwell-format silicon platform including thermometer, onto which sensors (pH, O2) screen-printed biosensors (glucose, lactate), were grafted/deposited. Microwells formed over fabricated give 5-well sensor strips interfaced with multipotentiostat via...

10.3390/s141120519 article EN cc-by Sensors 2014-10-30

Association studies have been employed to investigate the relationships between host single nucleotide polymorphisms (SNPs) and susceptibility pulmonary Tuberculosis (PTB). However, such candidate genetic markers not widely studied in Chinese population, especially with respect disease development from latent M. tuberculosis infection (LTBI).In this case-control study, 44 SNPs were examined a total of 600 participants (PTB patients, LTBI controls healthy without infection) Zhengzhou, China....

10.1186/1471-2334-13-511 article EN cc-by BMC Infectious Diseases 2013-10-31

Vascular calcification, a common complication in patients with chronic kidney disease, involves variety of mechanisms associated the regulation calcification-associated factors. Previous clinical studies have indicated that magnesium is involved reduction vascular calcification; however, mechanism underlying this process remains unknown. The aim present study was to investigate effects on β-glycerophosphate (β-GP)-induced calcification and mechanisms. Primary rat smooth muscle cells (VSMCs)...

10.3892/etm.2015.2215 article EN Experimental and Therapeutic Medicine 2015-01-26

In the process of isolated single liver cells coming together to form three-dimensional spheroids, undergo dramatic environmental changes. How respond these changes has not been well studied before. This study characterized functional and biochemical during spheroid formation maintenance. Spheroids were prepared in 6-well plates from freshly male Sprague rats by a gyrotatory-mediated method. Morphological formation, parameters spheroids evaluated over period 21 days culture. Liver was...

10.1002/jcb.10730 article EN Journal of Cellular Biochemistry 2003-11-05

Abstract: When anti-PD-1 drugs target healthy tissues, it may cause immune-related adverse events (irAEs). Hematological toxicities and renal reactions were rare; these recorded often clinically severe life-threatening. In this study, we first reported on an elderly esophageal cancer (ESC) case of cytokine release syndrome (CRS) irAEs induced by radiotherapy following drug treatment. A 69-year-old male patient with ESC was hospitalized December 2, 2019, after three cycles chemotherapy...

10.21037/apm-20-1310 article EN Annals of Palliative Medicine 2020-07-01

Vascular calcification, such as atherosclerosis, is a serious complication of chronic kidney disease that characterized by tunica media and has gained increasing attention from researchers. The commonly observed association between vascular calcification osteoporosis suggests link bone disorders. As microRNAs (miRNAs) have wide range gene regulation functions, cell proliferation, apoptosis, stress transdifferentiation, the current study aimed to determine whether miRNAs play vital role in...

10.3892/etm.2021.10468 article EN Experimental and Therapeutic Medicine 2021-07-19

Abstract Liver cells isolated from intact tissue can reaggregate to form three‐dimensional, multicellular spheroids in vitro. During this process, undergo a histological and environmental change. How respond biochemically change has not been studied detail previously. We have investigated some biochemical changes rat liver during the formation maintenance of spheroids. were male Sprague rats cultured by gyrotatory‐mediated method. shown isolation procedure triggered that increased arginine...

10.1002/jcb.10731 article EN Journal of Cellular Biochemistry 2003-11-05

Abstract Background Bioimpedance analysis (BIA) has been reported as helpful in identifying hypervolemia. Observation data showed that hypervolemic maintenance hemodialysis (MHD) patients identified using BIA methods have higher mortality risk. However, it is not known if BIA-guided fluid management can improve MHD patients’ survival. The objectives of the BOCOMO study are to evaluate outcome guided compared with standard care. Methods This a multicenter, prospective, randomized, controlled...

10.1186/1471-2369-13-120 article EN cc-by BMC Nephrology 2012-09-25

Vascular calcification such as arteriosclerosis, which is characterized by a of the tunica media, severe complication chronic kidney disease (CKD), contributing to high prevalence cardiovascular morbidity and mortality in patients with CKD. An essential step during development arteriosclerosis transdifferentiation/calcification vascular smooth muscle cells (VSMCs), resembling osteogenesis. Metabolic acidosis, common clinical manifestation CKD, known decrease calcification. To understand...

10.1080/10641963.2017.1384482 article EN Clinical and Experimental Hypertension 2018-02-08
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