Guangwei Chen

ORCID: 0000-0001-6578-8386
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About
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Research Areas
  • Ferroptosis and cancer prognosis
  • Lipid metabolism and biosynthesis
  • Tea Polyphenols and Effects
  • Phonocardiography and Auscultation Techniques
  • Digital Imaging in Medicine
  • Traditional Chinese Medicine Analysis
  • Healthcare and Venom Research
  • Catalytic C–H Functionalization Methods
  • Dental Research and COVID-19
  • ECG Monitoring and Analysis
  • Anatomy and Medical Technology
  • Catalytic Cross-Coupling Reactions
  • Medicinal Plant Pharmacodynamics Research
  • Bioinformatics and Genomic Networks
  • Bioactive Natural Diterpenoids Research
  • Phytochemistry and biological activity of medicinal plants
  • Gene expression and cancer classification
  • Biopolymer Synthesis and Applications
  • Curcumin's Biomedical Applications
  • PARP inhibition in cancer therapy
  • Photosynthetic Processes and Mechanisms
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Sulfur Compounds in Biology
  • Cancer-related Molecular Pathways
  • Hippo pathway signaling and YAP/TAZ

Guangzhou Medical University
2024-2025

Stomatology Hospital
2024-2025

Mackay Memorial Hospital
2023-2024

Zhongkai University of Agriculture and Engineering
2024

Key Laboratory of Guangdong Province
2024

Zhejiang Chinese Medical University
2020-2024

Fujian Agriculture and Forestry University
2023

Affiliated Hospital of Shaanxi University of Chinese Medicine
2023

Army Medical University
2018

Imperial College London
2010-2015

Abstract Aim Autotransplantation of teeth (ATT) is a viable biological method for addressing dental defects. The objective was to achieve occlusal reconstruction‐orientated ATT enhance functionality and obtain optimal location adjacency. This study proposes new concept guide (a fully guided system) position‐predictable ATT. Methodology included 30 transplants in 29 patients who were randomly divided into two groups during the initial examination using single‐blind method. experimental group...

10.1111/iej.14193 article EN International Endodontic Journal 2025-01-27

Tanshinone IIA is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that used to treat cardiovascular and inflammatory diseases. Recently, tanshinone was demonstrated induce cell death apoptosis variety of tumors. However, effect on human colon cancer cells not clearly understood yet. In this study, antigrowth apoptosis-eliciting effects IIA, as well its cellular mechanisms actions, were investigated Colo-205 cells....

10.1055/s-2008-1081299 article EN Planta Medica 2008-07-11

Phonocardiography is a widely used method of listening to the heart sounds and indicating presence cardiac abnormalities. Each cycle consists two major – S1 S2 that can be determine rate. The conventional acoustic signal acquisition involves placing sound sensor at chest where this most audible. Presented novel algorithm for detection use them extract rate from signals acquired by small placed neck. This achieves an accuracy 90.73 90.69%, with respect value provided commercial devices,...

10.1049/htl.2014.0095 article EN cc-by Healthcare Technology Letters 2015-02-01

The galloyl group in catechins was confirmed to be crucial for their health benefits. However, whether the catechins’ had a contribution anti-inflammation remains unclear. This study investigated properties and mechanisms of RAW264.7 cells by using ELISA, fluorometry, flow cytometer, Western blot, molecular docking. Results showed that enhanced inhibitory abilities on inflammatory cytokines (NO, PGE2, IL-1β, TNF-α) ROS release LPS-induced cells. suppression likely mediated delaying from...

10.3390/foods13162616 article EN cc-by Foods 2024-08-21

Cartilage injury is common in orthopedics and cartilage tissue engineering provides a therapeutic direction for regeneration. Albumin (ALB)–platelet-rich fibrin (PRF) speculated to be an ideal natural scaffold material theoretically as product derived from human venous blood. Through vitro vivo experiments, it was demonstrated that ALB–PRF displayed porous structure slowly released growth factors (TGF-β1, PDGF-AA, PDGF-AB, PDGF-BB, EGF, IGF-1 VEGF), conditioned media promoted proliferation,...

10.1080/09537104.2024.2414792 article EN cc-by Platelets 2024-10-21

This paper presents a method to automatically estimate lung tidal volumes from the acoustic signals generated in respiratory track. The signal is measured with an based sensor placed suprasternal notch. does not require any previous knowledge or modelling of individual track, and relies on just one calibration parameter. proposed algorithm tested 316 phases obtained 4 volunteers. subjects were simultaneously wearing Wright respirometer which was used as gold standard for comparison....

10.1109/embc.2014.6943885 article EN 2014-08-01

In recent years, plant essential oils have been confirmed as natural inhibitors of foodborne pathogens. Citrus reticulata Blanco cv. Tankan peel oil (CPEO) showed anti-Listeria monocytogenes (LM) activities, and this study investigated the associated mechanisms by using high-resolution electron microscope, fluorescence spectrometer, flow cytometer, potentiometer, transcriptome sequencing. The results that CPEO restrained LM growth at a minimum inhibitory concentration 2% (v/v). anti-LM...

10.3390/foods13233841 article EN cc-by Foods 2024-11-28

Power and current management in emerging wearable medical devices, intended to continuously monitor physiological signals, are crucial design issues. The overall size of the electronic part these systems is generally going be dominated by batteries. Unfortunately, options smaller batteries do not only come at expense a lower capacity hence shorter operation time. It also significantly constrains amount available that can used different blocks, as well their operating power supply voltage....

10.1109/iembs.2010.5626703 article EN 2010-08-01

Abstract An efficient palladacycle‐catalyzed aromatic carbonylation reaction of aryl formates with iodides or bromides has been developed. Commercially available and easily prepared were employed as carbonyl sources without the use external carbon monoxide. The present catalytic system shows broad functional group tolerance affords benzoate derivatives in good to excellent yields.

10.1002/cjoc.201300675 article EN Chinese Journal of Chemistry 2013-11-28

A series of novel spiro [4.4] and bicycle[3.3.0]-N-substitutedthiazolidine-2-thiones were obtained by a multicomponent reaction under mild conditions.Each the synthesized compounds was evaluated for their cytotoxic activity antibacterial activity.Some them exhibited significantly inhibited proliferation human tumor cell lines moderate inhibitory effect on fungi.A major challenge modern drug discovery is design highly efficient chemical sequences which provide maximum structural complexity...

10.3987/com-11-12147 article EN Heterocycles 2011-01-01

The aim of the present study was to search for differential gene expression and measure serum level a number biochemical parameters in cold Zheng (CZ) non-cold (NCZ) patients receiving hemodialysis. Hemodialysis (HD) were randomly selected from CZ NCZ groups. between-group differences assessed using complementary DNA (cDNA) microarray. Differential further validated by real-time reverse transcriptase polymerase chain reaction (RT-PCR). Our results demonstrated that up-regulation...

10.1142/s0192415x06003916 article EN The American Journal of Chinese Medicine 2006-01-01

Chinese fir (Cunninghamia lanceolata (Lamb.) Hook.) stands as one of the pivotal afforestation tree species and timber resources in southern China. Nevertheless, occurrence seed abortion a notably high proportion astringent seeds significantly curtail yield quality elite seeds, resulting substantial economic losses. The development is accompanied by significant physiological biochemical alterations. Here, first combined lipidomic metabolomic analysis was performed to gain comprehensive...

10.3390/ijms242015103 article EN International Journal of Molecular Sciences 2023-10-12

Background: Clinically, Fuzhengkangai formulation (FZKA) has been proven to have significant therapeutic effects on non-small lung cancer (NSCLC), although the mechanism is unknown. We aimed explore potential of FZKA in treatment NSCLC this study. Methods: obtained active components and targets by TCMSP. The target genes were searched from OMIM, GEO (GSE18842), GeneCards database. Cytoscape (3.7.2) software was used construct a “drug-compound-cross-target interaction” interaction network,...

10.2174/0109298665268153231024111622 article EN Protein and Peptide Letters 2023-11-14
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