- Forensic and Genetic Research
- Genetic diversity and population structure
- Political Economy and Marxism
- Yersinia bacterium, plague, ectoparasites research
- Race, Genetics, and Society
- Nutrition, Genetics, and Disease
- Genetic and phenotypic traits in livestock
- Forensic Anthropology and Bioarchaeology Studies
- Archaeology and ancient environmental studies
- Economic Theory and Institutions
- Economic Theory and Policy
- Clostridium difficile and Clostridium perfringens research
- Political Theory and Influence
- Evolutionary Psychology and Human Behavior
- Gut microbiota and health
- Genetic Mapping and Diversity in Plants and Animals
- Evolution and Genetic Dynamics
- Soviet and Russian History
- Identification and Quantification in Food
- Genomics and Rare Diseases
- Iron Metabolism and Disorders
- Food Security and Health in Diverse Populations
- Hemoglobinopathies and Related Disorders
- Animal Vocal Communication and Behavior
- Child Nutrition and Water Access
Éco-Anthropologie
2014-2024
University of Bern
2020-2024
SIB Swiss Institute of Bioinformatics
2020-2024
Université Paris Cité
2017-2024
Centre National de la Recherche Scientifique
2017-2024
Musée de l'Homme
2014-2022
Sorbonne Paris Cité
2017-2021
Sorbonne Université
2018
Danish Nature Agency
2015
Fondation Jean Dausset-CEPH
2014
fastsimcoal2 extends fastsimcoal, a continuous time coalescent-based genetic simulation program, by enabling the estimation of demographic parameters under very complex scenarios from site frequency spectrum maximum-likelihood framework.Other improvements include multi-threading, handling population inbreeding, extended input file syntax facilitating description scenarios, and more efficient simulations sparsely structured populations large chromosomes.fastsimcoal2 is freely available on...
The gut microbiomes of human populations worldwide have many core microbial species in common. However, within a species, some strains can show remarkable population specificity. question is whether such specificity arises from shared evolutionary history (codiversification) between humans and their microbes. To test for codiversification host microbiota, we analyzed paired metagenomes genomes 1225 individuals Europe, Asia, Africa, including mothers children. Between countries, parallel was...
The precise genetic origins of the first Neolithic farming populations in Europe and Southwest Asia, as well processes timing their differentiation, remain largely unknown. Demogenomic modeling high-quality ancient genomes reveals that early farmers Anatolia emerged from a multiphase mixing Asian population with strongly bottlenecked western hunter-gatherer after last glacial maximum. Moreover, ancestors went through period extreme drift during westward range expansion, contributing highly...
Research Article| June 01 1972 Mill and Cairnes the Emergence of Marginalism in England N. B. de Marchi Search for other works by this author on: This Site Google History Political Economy (1972) 4 (2): 344–363. https://doi.org/10.1215/00182702-4-2-344 Cite Icon Share Twitter Permissions Citation Marchi; England. 1 1972; doi: Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Dropdown Menu input auto suggest filter your...
The genetic adaptation of humans to the consumption milk from dairying animals is one most emblematic cases recent human evolution. While phenotypic change under selection, lactase persistence (LP), known, evolutionary advantage conferred persistent individuals remains obscure. One informative but underappreciated observation that not all populations whose ancestors had access genetically adapted become persistent. Indeed, Central Asian herders are mostly nonpersistent, despite their...
Research Article| June 01 1974 The Success of Mill's Principles N. B. de Marchi Search for other works by this author on: This Site Google History Political Economy (1974) 6 (2): 119–157. https://doi.org/10.1215/00182702-6-2-119 Cite Icon Share Facebook Twitter LinkedIn MailTo Permissions Citation Marchi; Principles. 1 1974; doi: Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Dropdown Menu input auto suggest filter...
Economists' knowledge of Malthus has been shaped very largely by the extensive Ricardo-Malthus correspondence, now widely known through Mr. Sraffa's edition Ricardo's writings. In his exchanges with Ricardo, appears as an insistent realist, countering strong cases references to specific historical experience, and calling attention what happens during intervals ignored in long-run equilibrium analysis.Four substantial letters from William Whewell have recently come light Papers, at Trinity...
There is a generally recognized gap, though of uncertain width, between the abstract analytical propositions Ricardian economics and concrete truth implicit in their use by contemporaries as guides to legislative action. The first purpose this paper inquire into nature economic statements made Ricardo, John Stuart Mill. Can key be construed as, did they intend them be, empirical statements? What tests accept measure theory? How bridge gap abstractions real world? A second purpose, which...
Abstract Objectives Sex‐specific genetic structures have been previously documented worldwide in humans, even though causal factors not always clearly identified. In this study, we investigated the impact of ethnicity, geography and social organization on sex‐specific structure Inner Asia. Furthermore, explored process ethnogenesis multiple ethnic groups. Methods We sampled DNA Central Northern Asia from 39 populations Indo‐Iranian Turkic‐Mongolic native speakers. focused data Y chromosome...
Modern and ancient genomes are not necessarily drawn from homogeneous populations, as they may have been collected different places at times. This heterogeneous sampling can be an issue for demographic inferences results in biased parameters incorrect model choice if properly considered. When explicitly accounted for, it result very complex models high data dimensionality that difficult to analyse. In this paper, we formally study the impact of such spatial temporal heterogeneity on...
When closely related individuals mate, they produce inbred offspring, which often have lower fitness than outbred ones. Geographical exogamy, by favouring matings between distant individuals, is thought to be an inbreeding avoidance mechanism; however, no data has clearly tested this prediction. Here, we took advantage of the diversity matrimonial systems in humans explore impact geographical exogamy on genetic and inbreeding. We collected ethno-demographic for 1,344 16 populations from two...
Most human populations exhibit an excess of high-frequency variants, leading to a U-shaped site-frequency spectrum (uSFS). This pattern has been generally interpreted as signature ongoing episodes positive selection, or evidence for mis-assignment ancestral/derived allelic states, but uSFS also observed in receiving gene flow from ghost population, structured populations, after range expansions. In order better explain the prevalence variants humans and other we describe here which patterns...
Abstract Characterizing animal dispersal patterns and the rational behind individuals’ transfer choices is a long‐standing question of interest in evolutionary biology. In wild western gorillas ( Gorilla gorilla ), one‐male polygynous species, previous genetic findings suggested that, when dispersing, females might favor groups with female kin to promote cooperation, resulting higher‐than‐expected within‐group relatedness. The extent male remains unclear studies showing conflicting results....
Admixture is a common biological phenomenon among populations of the same or different species. Identifying admixed tracts within individual genomes can provide valuable information to date admixture events, reconstruct ancestry-specific demographic histories, detect adaptive introgression, genetic incompatibilities, as well regions affected by (associative-) overdominance. Although many local ancestry inference (LAI) methods have been developed in last decade, their performance was accessed...
Since prehistoric times, southern Central Asia has been at the crossroads of movement people, culture, and goods. Today, Asian populations are divided into two cultural linguistic groups: Indo-Iranian Turko-Mongolian groups. Previous genetic studies unveiled that migrations from East contributed to spread in partial replacement populations. However, little is known about origin latters. To shed light on this, we compare data current-day - Yaghnobis Tajiks with genome-wide published ancient...
Melanistic Eurasian red squirrels Sciurus vulgaris are commonly found on the Danish island of Funen. They thought to represent native squirrel types and presently under threat from admixture with introduced squirrels. In response, a conservation program was started in 2009 that involves translocation melanistic Funen squirrel-free Langeland. Using mitochondrial DNA 101 historical modern samples throughout Denmark, we assess for first time population structure genetic diversity compared its...
Abstract The precise genetic origins of the first Neolithic farming populations, as well processes and timing their differentiation, remain largely unknown. Based on demogenomic modeling high-quality ancient genomes, we show that early farmers Anatolia Europe emerged from a multiphase mixing Near Eastern population with strongly bottlenecked Western hunter-gatherer after Last Glacial Maximum. Moreover, branch leading to is characterized by 2,500-year period extreme drift during its westward...
The Oxus Civilisation (or Bactrio-Margian Archaeological Complex, BMAC) was the main archaeological culture of Bronze Age in southern Central Asia. Paleogenetic analyses were previously conducted mainly on samples from eastern part BMAC. population associated with BMAC descends local Chalcolithic populations, some outliers steppe or South-Asian descent. Here, we present new genome-wide data for one individual Ulug-depe (Turkmenistan), sites, located at southwestern edge We demonstrate that...
Abstract Some gut microbes have cospeciated with hominids, but whether they further codiversified human populations is unclear. Here, we identify predominant microbial species sharing a parallel evolutionary history populations. Patterns of strain transfer between are generally consistent an African origin, and suggest long-term vertical transmission over thousands generations. We show the same strains also faithfully transmit mothers their children. Consistent development intimate...
Journal Article ON THE EARLY DANGERS OF BEING TOO POLITICAL AN ECONOMIST: THOROLD ROGERS AND 1868 ELECTION TO DRUMMOND PROFESSORSHIP Get access N. B. de MARCHI Duke University 1 Thanks are due to my colleagues Craufurd Goodwin and Professor Henry W. Spiegel, for their helpful comments on an earlier version of this paper. Search other works by author on: Oxford Academic Google Scholar Economic Papers, Volume 28, Issue 3, November 1976, Pages 364–380,...