A5050172166- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Pneumonia and Respiratory Infections
- Pulmonary Hypertension Research and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Anesthesia and Sedative Agents
- Nosocomial Infections in ICU
- Hemodynamic Monitoring and Therapy
- Healthcare Decision-Making and Restraints
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Vitamin K Research Studies
- Vitamin C and Antioxidants Research
- IgG4-Related and Inflammatory Diseases
- Healthcare cost, quality, practices
- Dielectric materials and actuators
- Extremum Seeking Control Systems
- Advanced Control Systems Design
- Organ Transplantation Techniques and Outcomes
- Adaptive Control of Nonlinear Systems
- Trauma and Emergency Care Studies
- Healthcare Systems and Technology
- Polyomavirus and related diseases
- Emergency and Acute Care Studies
- Venous Thromboembolism Diagnosis and Management
Asan Medical Center
2014-2025
University of Ulsan
2014-2025
Ulsan College
2014-2025
Waitemata District Health Board
2023
Abstract Background Although several trials were conducted to optimize the oxygenation range in intensive care unit (ICU) patients, no studies have yet reached a universal recommendation on optimal partial pressure of oxygen arterial blood (PaO 2 ) patients with sepsis. Our aim was evaluate whether relatively high tension is associated longer survival sepsis compared conservative tension. Methods From Korean Sepsis Alliance nationwide registry, treated liberal PaO ≥ 80 mm Hg) 1:1 matched...
Vitamin C has shown several beneficial effects on sepsis in preclinical studies. However, clinical data supporting these reports are scarce. This study aimed to evaluate whether adjunctive intravenous vitamin therapy could reduce hospital mortality patients with severe or septic shock requiring mechanical ventilation.For this retrospective cohort study, consecutive medical ICU ventilation were included. The classified into the control groups depending administration of (2 g every 8 hours)....
Abstract Background The optimal strategy for fluid management during the first few days of ICU in sepsis patients remains controversial. We aimed to investigate impact cumulative balance three on mortality with sepsis. Methods This study analyzed prospectively collected data from Korean Sepsis Alliance Database, which registered 11,981 20 hospitals. selected propensity score-matched cohorts consisting a negative or positive days: admission midnight as D1 cohort, until second D2 and third D3...
Background: Current international guidelines recommend against deep sedation as it is associated with worse outcomes in the intensive care unit (ICU).However, Korea prevalence of and its impact on patients ICU are not well known.Methods: From April 2020 to July 2021, a multicenter, prospective, longitudinal, noninterventional cohort study was performed 20 Korean ICUs.Sedation depth extent divided into light using mean Richmond Agitation-Sedation Scale value within first 48 hours.Propensity...
Changes in sedation levels over a long time patients who are mechanically ventilated unknown. Therefore, we investigated the long-term of these by classifying them into different longitudinal patterns.This was multicentre, prospective, longitudinal, and observational study.Twenty intensive care units (ICUs) spanning several medical institutions Korea.Patients received mechanical ventilation sedatives ICU within 48 hours admission between April 2020 July 2021.The primary objective this study...
Abstract Background Acute exacerbation of interstitial lung disease (AE-ILD) significantly impacts prognosis, leading to high mortality rates. Although transplantation is a life-saving treatment for selected patients with ILD, its outcomes in those presenting AE-ILD have yielded conflicting results compared stable ILD. This study aims investigate the impact pre-existing AE on prognosis ILD who underwent transplantation. Method We conducted single-center retrospective by reviewing medical...
Intrathoracic involvement of immunoglobulin G4 (IgG4)-related disease has recently been reported. However, a subset the presenting as interstitial lung is rare. Here, we report case 35-year-old man with IgG4-related manifestations similar to those disease. Chest computed tomography showed diffuse ground glass opacities and rapidly progressive pleural subpleural fibrosis in both upper lobes. Histological findings lymphoplasmacytic infiltration an increased number IgG4-positive plasma cells....
Continuous infusion of beta-lactam antibiotics has emerged as an alternative for the treatment sepsis because favourable pharmacokinetics continuous infusion. This study aimed to evaluate survival benefits vs. intermittent piperacillin-tazobactam in critically ill patients with sepsis. We retrospectively conducted a single-centre adult who met Sepsis-3 criteria and were treated at medical ICU within 48 h after hospitalisation between 1 May 2018 30 April 2020. The primary outcome was...
Herein, a new triboelectric energy‐harvesting method by direct transfer‐triboelectric nanogenerator (DT‐TENG) in streaming flow is proposed. Previously, most of the fluid‐based‐triboelectric nanogenerators (Flu‐TENGs) generate electricity electrostatic induction, which one indirect charge transfer methods. To enhance effect liquid from surface dielectric material, negative treatment focused. The significance novel to high output power Flu‐TENG first reported herein. From experiment, maximum...
The efficacy of extended meropenem infusions in patients with nosocomial pneumonia is not well defined. Therefore, we compared the clinical outcomes versus intermittent treatment pneumonia. We performed a retrospective analysis adult who had been treated for at medical ICU between 1 May 2018 and 30 April 2020. primary outcome was mortality 14 days. Overall, 64 underwent an infusion 97 were included this study. At days, 10 (15.6%) group 22 (22.7%) died (adjusted hazard ratio (HR), 0.55; 95%...
We aimed to identify a vasoreactive subset of patients with idiopathic pulmonary arterial hypertension (IPAH) in Korea and show their clinical characteristics prognosis. Data on who were diagnosed IPAH at Asan Medical Center between January 1994 March 2013 retrospectively collected. Acute vasodilator testing was performed inhaled nitric oxide during diagnostic right heart catheterization. A positive acute response defined as reduction mean pressure (PAP) ≥10 mmHg an absolute level PAP <40...
Abstract Background There is an argument whether the delayed intubation aggravate respiratory failure in Acute distress syndrome (ARDS) patients with coronavirus disease 2019 (COVID-19). We aimed to investigate effect of high-flow nasal cannula (HFNC) before mechanical ventilation on clinical outcomes mechanically ventilated COVID-19. Methods This retrospective cohort study included who were diagnosed COVID-19 and admitted intensive care unit (ICU) between February 2020 December 2021 at Asan...
Background According to the rapid response system’s team composition, responding teams were named as (RRT), medical emergency (MET), and critical care outreach. A RRT is often a nurse-led team, whereas MET physician-led that mainly plays role of an efferent limb. As few multicenter studies have focused on METs, we comprehensively analyzed cases for which METs activated. Methods We retrospectively The study population consisted subjects over 18 years age who admitted in general ward from...
This paper aims to develop a novel continuous exact differentiator determine the first-order derivative of given signal in case unknown upper-bounded second-order with simple tuning process. In addition, an improved convergence time and estimation accuracy can be successfully attained by employing innovative differentiator-generating functions. Furthermore, stability proposed is theoretically verified through Lyapunov theory. Finally, several numerical simulations are conducted demonstrate...
Ji, Wonjun1; Kwon, Byoung Soo1; Moon, Do Sik1; Ahn, Jee Hwan1; Woo, Ala1; Oh, Dong Kyu1; Huh, Jin Won1; Hong, Sang-Bum1; Koh, Younsuck2; Lim, Chae-Man1 Author Information
Diffuse alveolar hemorrhage (DAH) may occur with vasculitis, infection, and coagulation disorders. In patients hematologic malignancies such as leukemia, lymphoma multiple myeloma, the risk of death from DAH is 70%. Although their effectiveness remains uncertain, corticosteroids are mainstay treatment. It not easy to determine use because adverse effects worsening infections, gastrointestinal (GI) bleeding poor blood glucose control. Retrospective analysis was performed at a single medical...