A5005035972- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Cardiac Arrest and Resuscitation
- Viral Infections and Vectors
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Vector-borne infectious diseases
- Mechanical Circulatory Support Devices
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Agriculture and Farm Safety
- Bacterial Identification and Susceptibility Testing
- Long-Term Effects of COVID-19
- Thermal Regulation in Medicine
- Antibiotic Resistance in Bacteria
- Soft tissue tumors and treatment
- Musculoskeletal pain and rehabilitation
- Airway Management and Intubation Techniques
- Peripheral Neuropathies and Disorders
- Climate Change and Health Impacts
- Lymphadenopathy Diagnosis and Analysis
Jeju National University
2011-2024
Jeju National University Hospital
2012-2024
University of Ulsan
2018
Asan Medical Center
2018
Ulsan College
2018
Abstract Background Timely administration of antibiotics is one the most important interventions in reducing mortality sepsis. However, administering within a strict time threshold all patients suspected with sepsis will require huge amount effort and resources may increase risk unintentional exposure to broad-spectrum without infection its consequences. Thus, controversy still exists on whether clinicians should target different time-to-antibiotics thresholds for versus septic shock....
Abstract Background Numerous epidemiological studies investigating gender-dependent clinical outcomes in sepsis have shown conflicting evidence. This study aimed to investigate the effect of gender on in-hospital mortality due according age group. Methods used data from Korean Sepsis Alliance, an ongoing nationwide prospective multicenter cohort 19 participating hospitals South Korea. All adult patients diagnosed with emergency departments between September 2019 and December 2021 were...
The prevalence of obesity is increasing in the intensive care unit (ICU). Although a known risk factor for chronic kidney disease, its association with early sepsis-associated acute injury (SA-AKI) and their combined patient outcomes warrant further investigation.
The ratio of oxygen saturation (ROX) index, defined as the (SpO2)/fraction inspired (FiO2) to respiratory rate, can help identify patients with hypoxemic failure at high risk for intubation following high-flow nasal cannula (HFNC) initiation; however, whether it is effective predicting in coronavirus disease 2019 (COVID-19) receiving HFNC remains unknown. Moreover, SpO2/FiO2 has been assessed a prognostic marker acute failure. This study aimed determine utility ROX index and predictors...
The incidence of sepsis with identified fungal pathogens is increasing and associated higher morbidity mortality. Co-infection infections in COVID-19 patients attracting clinical attention. This study examines the epidemiology, risk factors, outcomes among pathogens. We conducted a nationwide cohort adult from Korean Sepsis Alliance Database South Korea between September 2019 December 2021. 407 documented pathogens, categorized according to presence hemato-oncologic malignancies. Of 11,981...
The potential relationship between vitamin D (VitD) status and metabolic control in patients with type 2 diabetes mellitus (T2DM) warrants further study.We aimed to evaluate the serum 25-hydroxyvitamin [25(OH)D] level various parameters T2DM.We analyzed retrospectively data from 276 Korean T2DM whose 25(OH)D was measured our hospital.Nondiabetic healthy subjects who visited hospital for health screening were selected as group (Non-DM, n=160).Compared subjects, had a lower (15.4±0.5 vs....
Mortality rates associated with sepsis have increased progressively in Korea, but domestic epidemiologic data remain limited. The objective of this study was to investigate the characteristics, management and clinical outcomes patients Korea.This is a multicenter retrospective cohort study. A total 64,021 adult who visited an emergency department (ED) within one 19 participating hospitals during 1-month period were screened for eligibility. Among these, diagnosed based on third International...
Limited data are available on the mortality rates of patients receiving extracorporeal membrane oxygenation (ECMO) support for coronavirus disease 2019 (COVID-19). We aimed to analyze relationship between COVID-19 and clinical outcomes ECMO.
To investigate the impact of normothermia on compliance with sepsis bundles and in-hospital mortality in patients who present to emergency departments.Retrospective multicenter observational study.Nineteen university-affiliated hospitals Korean Sepsis Alliance participated this study. Data were collected regarding visited departments for during 1-month period. The divided into three groups based their body temperature at time triage department (i.e., hypothermia [< 36°C] vs [36-38°C]...
Abstract Background There is limited information about the outcomes of polymicrobial bloodstream infections in patients with sepsis. We aimed to investigate compared monomicrobial infections. Methods This study used data from Korean Sepsis Alliance Registry, a nationwide database prospective observational sepsis cohort. Adult September 2019 December 2021 at 20 tertiary or university-affiliated hospitals South Korea were analyzed. Results Among 3,823 infections, 429 them (11.2%) had The crude...
Objective: This study aimed to investigate the characteristics and epidemiological trends of pediatric injuries among patients visiting emergency departments (EDs) on Jeju Island. Method:Employing a community-level serial cross-sectional analysis, we targeted aged 18 years or younger who visited EDs for over ten-year period.The data, sourced from Injury Surveillance System (JISS), facilitated comprehensive examination injury trends.This included an evaluation annual incidence overall in...
Based on sparse evidence, the current Surviving Sepsis Campaign guideline suggests that critically ill patients with sepsis be admitted to intensive care unit (ICU) within 6 h. However, limited ICU bed availability often makes immediate transfer difficult, and it is unclear whether all will benefit from early admission ICU. Therefore, purpose of this study was determine association between timing mortality in hospital-onset sepsis.This nationwide prospective cohort analyzed ICUs 19 tertiary...
The intensive care unit (ICU) admission of patients with hematologic malignancies is gradually increasing. Life-threatening events are common, and acute respiratory distress syndrome (ARDS) one the most critical conditions. aim this study was to investigate clinical characteristics outcomes ARDS in hematological admitted ICU.A retrospective performed on all a single tertiary teaching hospital between 2008 2015. Data treatment were collected determine associated ICU mortality.During 8-year...
We aimed to investigate the prevalence of low back pain (LBP) and its associated agricultural work-related, biomechanical factors among this population.We analyzed initial survey data from Safety for Agricultural Injury Farmers cohort study involving adult farmers in Jeju Island. The LBP was calculated with factors.In total, 1,209 participants were included analysis. overall 23.7%. Significant associations type farming activity, length career, prior injury within 1 year, stress levels....
Elderly patients with coronavirus disease 2019 (COVID-19) have a high severity and mortality. However, the use of frailty scale score to predict in-hospital mortality in elderly is not well established. Therefore, this study, we investigated these scores COVID-19 cases elderly.This multicenter retrospective study included severe admitted seven hospitals Republic Korea from February 2020 2021. We evaluated patients' Acute Physiology Chronic Health Evaluation (APACHE) II score; confusion, urea...
Amniotic fluid embolism (AFE) is a rare but fatal obstetric emergency, which characterized by sudden cardiovascular collapse, respiratory failure, and disseminated intravascular coagulation (DIC). We report case of cardiac arrest due to an amniotic-fluid was successfully treated with veno-arterial extracorporeal membrane oxygenation (ECMO). A 32-year-old female at 39.1 weeks gestation scheduled for induction labor. During labor, generalized tonic-clonic seizure developed followed dyspnea...
Sepsis is the most common cause of death in hospitals, and intra-abdominal infection (IAI) accounts for a large portion causes sepsis. We investigated clinical outcomes factors influencing mortality patients with sepsis due to IAI.This post-hoc analysis prospective cohort study included 2126 who visited 16 tertiary care hospitals Korea (September 2019-February 2020). The 219 aged > 19 years were admitted intensive units owing caused by IAI.The incidence septic shock was 47% significantly...
For patients hospitalized with coronavirus disease 2019 (COVID-19) who require supplemental oxygen, the evidence of optimal duration corticosteroid is limited. This study aims to identify whether long-term use corticosteroids associated decreased mortality.
Abstract Background The optimal strategy for fluid management during the first few days of ICU in sepsis patients remains controversial. We aimed to investigate impact cumulative balance three on mortality with sepsis. Methods This study analyzed prospectively collected data from Korean Sepsis Alliance Database, which registered 11,981 20 hospitals. selected propensity score-matched cohorts consisting a negative or positive days: admission midnight as D1 cohort, until second D2 and third D3...
Background Mycobacterial identification in active pulmonary tuberculosis (APTB) is confirmative, even though successful rates using self-expectorated sputum are limited. Sputum specimens collected by hypertonic saline nebulization showed higher bacteriologic diagnostic sensitivities over those of self-expectoration, mostly studied smear-negative or sputum-scarce patients. The efficacy induced was rarely assessed real clinical settings. Methods A prospective randomized case-control study...
Abstract Background Hospital-onset sepsis is associated with a higher in-hospital mortality rate than community-onset sepsis. Many hospitals have implemented rapid response teams (RRTs) for early detection and timely management of at-risk hospitalized patients. However, the effectiveness an all-day RRT over non-all-day in reducing risk patient hospital-onset unclear. We aimed to determine effect RRT’s operating hours on inpatient patients Methods conducted nationwide cohort study adult...
BackgroundHuman cytomegalovirus (HCMV) is a common herpesvirus that can cause range of symptoms, from mild conditions such as fevers to severe illnesses like pneumonia. Early and accurate diagnosis HCMV infection crucial, particularly for vulnerable populations with limited medical care. However, current diagnostic methods are often expensive, time-consuming, require skilled technicians.Materials methodsWe developed an HCMV-RPA-CRISPR platform the rapid cost-effective detection infection....