Olena Mitchenko
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Cancer, Lipids, and Metabolism
- Diet and metabolism studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Nutrition, Genetics, and Disease
- Health Systems, Economic Evaluations, Quality of Life
- Human Health and Disease
- Hormonal Regulation and Hypertension
- Lipid metabolism and disorders
- Microbial Metabolism and Applications
- Nutritional Studies and Diet
- Menopause: Health Impacts and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Thyroid Disorders and Treatments
- Regulation of Appetite and Obesity
- Consumer Attitudes and Food Labeling
- Healthcare Systems and Public Health
- Liver Disease Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Fatty Acid Research and Health
- Renal function and acid-base balance
- Estrogen and related hormone effects
- Adipose Tissue and Metabolism
National Scientific Center "M.D. Strazhesko Institute of Cardiology"
2012-2022
National Academy of Medical Sciences of Ukraine
2015-2022
European Atherosclerosis Society
2021
Ukrainian Academy of Banking of the National Bank of Ukraine
2019
Institute of Urology of the National Academy of Medical Sciences of Ukraine
2004
1.1. Cardiovascular disease and dyslipidemia: prevalence global economic impact Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, reaching 31% deaths in 2012 [1]. In particular, atherosclerosis ischemic heart (IHD) main causes premature death Europe responsible for 42% women 38% men under 75 years old [2]. The impact CVD is estimated to have been US $906 billion 2015 expected rise by 22% 2030 [3]. also represent major disability developed countries. It has that...
Abstract Background and Aims Overweight obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence individuals with heterozygous familial hypercholesterolaemia (HeFH) whether they confer additional of ASCVD independent LDL cholesterol (LDL-C) remains unclear. Methods Cross-sectional analysis was conducted 35 540 patients HeFH across 50 countries, EAS FH Studies Collaboration registry. Prevalence World Health...
Proteins play a crucial role in metabolism, maintaining fluid and acid-base balance antibody synthesis. Dietary proteins are important nutrients classified into: 1) animal (meat, fish, poultry, eggs dairy), and, 2) plant (legumes, nuts soy). modification is one of the most lifestyle changes that has been shown to significantly decrease risk cardiovascular (CV) disease (CVD) by attenuating related factors. The CVD burden reduced optimum diet through replacement unprocessed meat with low...
The potential for global collaborations to better inform public health policy regarding major non-communicable diseases has been successfully demonstrated by several large-scale international consortia. However, the true impact of familial hypercholesterolaemia (FH), a common genetic disorder associated with premature cardiovascular disease, is yet be reliably ascertained using similar approaches. European Atherosclerosis Society FH Studies Collaboration (EAS FHSC) new initiative...
Background Little is known about the achievement of low density lipoprotein cholesterol (LDL-C) targets in patients at cardiovascular risk receiving stable lipid-lowering therapy (LLT) countries outside Western Europe. Methods This cross-sectional observational study was conducted 452 centres (August 2015−August 2016) 18 Eastern Europe, Asia, Africa, Middle East and Latin America. Patients ( n = 9049) treated for ≥3 months with any LLT whom an LDL-C measurement on available within previous...
<h2>Summary</h2><h3>Background</h3> Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults were diagnosed before age 18 years via current diagnostic approaches, which derived from observations in adults. We aimed to characterise and adolescents heterozygous (HeFH) understand approaches the identification management inform future public health strategies. <h3>Methods</h3> For this cross-sectional study, we assessed younger...
Atherosclerotic cardiovascular disease (ASCVD) and consequent acute coronary syndromes (ACS) are substantial contributors to morbidity mortality across Europe. Fortunately, as much two thirds of this disease's burden is modifiable, in particular by lipid-lowering therapy (LLT). Current guidelines based on the sound premise that, with respect low-density lipoprotein cholesterol (LDL-C), "lower better for longer", recent data have strongly emphasised need also "the earlier better". In addition...
Despite great recent progress, familial hypercholesterolemia (FH) is still underestimated, under-diagnosed and thus undertreated worldwide. We have very little information on exact prevalence of patients with FH in the Central, Eastern Southern Europe (CESE) region. The aim study was to describe epidemiological situation CESE region from data available.All local leaders ScreenPro project were asked provide (a) expert guess (b) medical facilities focused already place (c) diagnostic criteria...
Abstract Background Statin intolerance is a clinical syndrome whereby adverse effects associated with statin therapy (most commonly muscle symptoms) result in the discontinuation of therapy. increased risk cardiac outcomes. Many patients who initially experience are able to tolerate some extent. Careful stepwise diagnosis and management individuals essential enable optimal reduction cardiovascular risk. Purpose In this Position Paper International Lipid Expert Panel (ILEP), we present step...
Familial hypercholesterolemia (FH) is a genetic disorder with well-known transmission and clinical course. Despite great recent progress, FH still underestimated, under-diagnosed thus undertreated. Furthermore it represents significant healthcare challenge as common risk factor for the premature development of coronary heart disease. The ScreenPro Project an international network project aiming at improving complex care - from timely screening, through diagnosis to up-to-date treatment...
Метою даного дослідження був субаналіз поширеності та виявлення артеріальної гіпертензії (АГ) серед когорти респондентів із надлишковою масою тіла ожирінням залежно від ступеня типу ожиріння в рамках великого популяційного визначення факторів ризику, проведеного нами Україні на міській популяції у 2009–2013 рр. Визначено, що проаналізованій населення України нормальну масу мали лише 29,3 %, а 70,7 % — сумарно надлишкову I–III ступеня. Відзначалася тенденція до збільшення надлишкової маси з...