A5047362656- Cardiac Health and Mental Health
- Streptococcal Infections and Treatments
- Cardiovascular and exercise physiology
- Lipoproteins and Cardiovascular Health
- Heart Rate Variability and Autonomic Control
- Long-Term Effects of COVID-19
- Antimicrobial Resistance in Staphylococcus
- Cardiac Imaging and Diagnostics
- Pain Management and Treatment
- Toxin Mechanisms and Immunotoxins
- Blood Pressure and Hypertension Studies
- Public Health and Nutrition
- Cardiac Valve Diseases and Treatments
- Cardiovascular Effects of Exercise
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- IL-33, ST2, and ILC Pathways
- Fatty Acid Research and Health
- Inflammasome and immune disorders
- Stroke Rehabilitation and Recovery
- Antibiotic Use and Resistance
- Macrophage Migration Inhibitory Factor
- Acute Myocardial Infarction Research
- Sodium Intake and Health
National Brain Centre
2017-2025
University of Indonesia
2017-2025
Sapporo Science Center
2024
Indonesian Pediatric Society
2024
Pembuluh Darah Harapan Kita
2019
University Malaya Medical Centre
2019
University of North Sumatra
2017-2019
Malikussaleh University
2019
Chang Gung University
2019
Chang Gung Memorial Hospital
2019
Abstract Background and Aims Overweight obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence individuals with heterozygous familial hypercholesterolaemia (HeFH) whether they confer additional of ASCVD independent LDL cholesterol (LDL-C) remains unclear. Methods Cross-sectional analysis was conducted 35 540 patients HeFH across 50 countries, EAS FH Studies Collaboration registry. Prevalence World Health...
<h2>Summary</h2><h3>Background</h3> Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults were diagnosed before age 18 years via current diagnostic approaches, which derived from observations in adults. We aimed to characterise and adolescents heterozygous (HeFH) understand approaches the identification management inform future public health strategies. <h3>Methods</h3> For this cross-sectional study, we assessed younger...
<ns3:p>Group A Streptococcus (GAS) is a widely distributed bacterium that Gram-positive and serves as the primary cause of acute rheumatic fever (ARF) episodes. Rheumatic heart disease (RHD) sequela resulting from repeated ARF attacks which are also caused by GAS infections. ARF/RHD morbidity mortality rates incredibly high in low- middle-income countries. This closely related to poor levels sanitation causes enhanced incidence Management carditis RHD cases quite challenging, particularly...
Background: To date, there is no reference for a 6-min walk test distance (6-MWD) immediately after cardiac surgery. Therefore, this study aimed to identify the determinants and generate equations prediction 6-MWD in patients Methods: This cross-sectional of (6-MWT) prior participation rehabilitation (CR) program coronary artery bypass surgery (CABG) or valve The 6-MWT were carried out gymnasium CR Available demographic clinical data analyzed 6-MWD. Results: obtained 1,509 CABG 632 all was...
Beyond the acute phase, a considerable proportion of patients recovering from coronavirus disease 2019 (COVID-19) experience long-term sequelae that profoundly impact their quality life, particularly physical fitness. This study aims to assess effect home-based breathing and chest mobility exercise on cardiorespiratory functional capacity long COVID with cardiovascular comorbidity. In this randomized, controlled, single-blind clinical trial, 46 comorbidities were randomly assigned either...
Rheumatic mitral stenosis continues to be prevalent in developing countries, notably endemic areas. Over the last few decades, percutaneous balloon valvuloplasty (PBMV) has been established as a lower-cost alternative treatment for (MS) low-to-middle-income countries. PBMV also suggested an effective and safe modality. This study aims analyse survival of rheumatic MS patients treated with compared those valve surgery (MVS).This was national, single-centre, longitudinal using analysis method...
Introduction Rheumatic heart disease (RHD) is a major burden in developing countries and accounts for 80% of all people living with the disease, where it causes most cardiovascular morbidity mortality children young adults. Chronic inflammation fibrosis valve tissue due to chronic RHD will cause calcification thickening impacted valves, especially mitral valve. This fibrogenesis enhanced by production angiotensin II increased transforming growth factor β expression later binding...
Abstract Background Resistance training is commonly recommended as part of secondary prevention for post-coronary artery bypass graft (CABG) patients in conjunction with aerobic exercise. Despite its potential benefits, there currently a lack studies investigating the impact resistance on proprotein convertase subtilisin kexin 9 (PCSK9). Aim To evaluate effect intensive (PCSK9) levels among post-CABG undergoing cardiac rehabilitation (CR). Methods In this prospective, open-label, randomized...
Objective: External counterpulsation (ECP) provides long-term benefits of improved anginal frequency and exercise tolerance in patients with refractory angina (RA). This is postulated as a result angiogenesis endothelial function through an increase shear stress. Angiogenesis mainly represented by vascular growth factor-A (VEGF-A) its receptor, factor receptor-2 (VEGFR-2). The microRNA-92a (miR-92a) flow-sensitive miRNA that regulates atherosclerosis response to Thus, ECP beneficial effect...
Exosomes, as one of the extracellular vesicles' subgroups, played an important role in cell to communication. The cargos and surface protein exosomes have been known affect cardiovascular system both positively negatively chronic heart failure, ischemic disease, atherosclerosis. There several that emerged potential diagnostic prognostic markers patients. However, conditions affecting patients method isolation should be considered create a standardized normal value components. CPC-derived...
<ns3:p>Group A Streptococcus (GAS) is a widely distributed bacterium that Gram-positive and serves as the primary cause of acute rheumatic fever (ARF) episodes. Rheumatic heart disease (RHD) sequela resulting from repeated ARF attacks which are also caused by GAS infections. ARF/RHD morbidity mortality rates incredibly high in low- middle-income countries. This closely related to poor levels sanitation causes enhanced incidence Management carditis RHD cases quite challenging, particularly...
Background: Acute decompensated heart failure (ADHF) is a cardiovascular disease with high mortality and readmission rates. Currently, insulin resistance has been reported to predict prognosis of ADHF patients. Triglyceride glucose index (TyG) now proposed as an independent predictor risk simple marker resistance. However, the association between TyG 30-days 6 months after hospitalization remains unclear.
 Objective: To investigate 30-day in patients.
 Methods: The study was...
Abstract Background Galectin-3 is a soluble b-galactosidase-binding lectin which plays an important role as the main regulator in inflammatory and fibrosis processes released by macrophage cells. often referred next-generation biomarker detecting early stages of various diseases. Several recent studies have aimed to unveil potential plasma prognostic indicator for coronary artery disease (CAD). No prior research has been conducted Indonesia evaluate value individuals with CAD. Objective This...
Digital technology has become integral to the practice of medicine, especially in response COVID-19 pandemic and its associated lockdowns social distancing measures. It allowed patients, including those undergoing cardiac rehabilitation, access healthcare services regardless their geographical location. However, widespread integration digital on a national scale presents numerous challenges. These obstacles encompass various aspects, patient–physician relationships, legal policies, health...
Introduction With atherosclerotic cardiovascular disease (ASCVD) cases increasing in Indonesia, there is a growing need to identify high-risk patients for recurrent events. Risk stratification could guide optimal secondary preventive therapy. Understanding the ASCVD direct inpatient costs further provide insight reducing economic burden that comes with Indonesia's high number cases. However, significant gap Indonesian large-scale research on both of these valuable data. Employing SMART-REACH...
Abstract Background Techniques for treating difficult chronic total occlusions (CTOs) have evolved with the discovery of tip detection-antegrade dissection re-entry (TDADR) guided by intravascular ultrasound (IVUS). This case demonstrates TDADR as a viable bailout in failed subintimal tracking and (STAR) technique. Case summary A 78-year-old man stable angina on optimal medical therapy had exertional pectoris secondary to residual CTO lesion left circumflex coronary (LCX) artery....
<ns3:p>Group A Streptococcus (GAS) is a widely distributed bacterium that Gram-positive and serves as the primary cause of acute rheumatic fever (ARF) episodes. Rheumatic heart disease (RHD) sequela resulting from repeated ARF attacks which are also caused by GAS infections. ARF/RHD morbidity mortality rates incredibly high in low- middle-income countries. This closely related to poor levels sanitation causes enhanced incidence Management carditis RHD cases quite challenging, particularly...
There remains great heterogeneity in the availability of data and approaches managing hypertension Asia-Pacific. A narrative review was performed to better understand epidemiology challenges care provision regionally. The obtained were discussed under five domains: epidemiology; hospitalisation financial impact; medication prescription; national guidelines, societies measures; barriers hypertension. Sixteen countries included, with prevalence ranging between 10.6% 48.3%. Rates undiagnosed,...
Background: Rheumatic heart disease still become a major concern in developing countries. Recent studies showed the benefits of early phase II cardiac rehabilitation (CR) on improving exercise capacity but evidence patients after rheumatic mitral valve surgery due to is limited. This study aims investigate effects CR program increasing patients.
 Methods: cohort retrospective study. A review medical records identified 254 who underwent between July 2009 – June 2019. Effects was assessed...
Background. Cardiac rehabilitation (CR) has been reported as effective for improving coronary risk factors and increasing exercise tolerance in patients with artery disease (CAD) after cardiac events. It may be performed 3 stages: acute (phase I), subacute II), chronic III). In Indonesia, most programs have phase I some II, whereas III not often it was covered by national health insurance. Objectives . We assessed the beneficial effects of 6-month hospital-based comprehensive on physical...