A5076456910- Advanced Fluorescence Microscopy Techniques
- Digital Holography and Microscopy
- Optical Coherence Tomography Applications
- Chaos-based Image/Signal Encryption
- Advanced Optical Imaging Technologies
- Orbital Angular Momentum in Optics
- Advanced Photocatalysis Techniques
- Neural dynamics and brain function
- Image Processing Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Neuroscience and Neuropharmacology Research
- Photonic and Optical Devices
- Memory and Neural Mechanisms
- Advanced Steganography and Watermarking Techniques
- Cell Image Analysis Techniques
- Near-Field Optical Microscopy
- Optical measurement and interference techniques
- CCD and CMOS Imaging Sensors
- Advanced X-ray Imaging Techniques
- Advanced Vision and Imaging
- Single-cell and spatial transcriptomics
- Advanced Fiber Laser Technologies
- Photoreceptor and optogenetics research
- Neuroendocrine regulation and behavior
- Advanced Electron Microscopy Techniques and Applications
Guangzhou University of Chinese Medicine
2025
Heilongjiang University
2021-2024
Ministry of Education of the People's Republic of China
2021-2024
Peking University
2012-2024
Institute of Molecular Medicine
2024
North University of China
2024
Imaging Center
2024
University of California, Los Angeles
2019-2023
South China Institute of Collaborative Innovation
2022-2023
Center for Life Sciences
2022-2023
Information security and authentication are important challenges facing society. Recent attacks by hackers on the databases of large commercial financial companies have demonstrated that more research development advanced approaches necessary to deny unauthorized access critical data. Free space optical technology has been investigated many researchers in information security, encryption, authentication. The main motivation for using optics photonics is waveforms possess complex degrees...
Imaging large-population, single-cell fluorescent dynamics in freely behaving animals larger than mice remains a key endeavor of neuroscience. We present large-field-of-view open-source miniature microscope (MiniLFOV) designed for large-scale (3.6 mm × 2.7 mm), cellular resolution neural imaging rats. It has an electrically adjustable working distance up to 3.5 ± 100 μm, incorporates absolute head orientation sensor, and weighs only 13.9 g. The MiniLFOV is capable both deep brain cortical...
Observing the various anatomical and functional information that spans many spatiotemporal scales with high resolution provides deep understandings of fundamentals biological systems. Light-field microscopy (LFM) has recently emerged as a scanning-free, scalable method allows for high-speed, volumetric imaging ranging from single-cell specimens to mammalian brain. However, prohibitive reconstruction artifacts severe computational cost have thus far limited broader applications LFM. To...
Abstract The rapid development of scientific CMOS (sCMOS) technology has greatly advanced optical microscopy for biomedical research with superior sensitivity, resolution, field-of-view, and frame rates. However, sCMOS sensors, the parallel charge-voltage conversion different responsivity at each pixel induces extra readout pattern noise compared to charge-coupled devices (CCD) electron-multiplying CCD (EM-CCD) sensors. This can produce artifacts, deteriorate imaging capability, hinder...
Two modified Gerchberg–Saxton (GS) iterative phase retrieval algorithms are proposed. The first we refer to as the spatial perturbation GS algorithm (SPP GSA). second is a combined hybrid input–output (GS/HIOA). In this paper (Part I), it demonstrated that SPP and GS/HIO both much better at avoiding stagnation during retrieval, allowing them successfully locate superior solutions compared with either or HIO algorithms. performances of also compared. Then, error reduction (ER) (ER/HIOA)...
Visualizing diverse anatomical and functional traits that span many spatial scales with high spatio-temporal resolution provides insights into the fundamentals of living organisms. Light-field microscopy (LFM) has recently emerged as a scanning-free, scalable method allows for high-speed, volumetric brain imaging. Given those promising applications at tissue level, its other extreme, this highly-scalable approach holds great potential observing structures dynamics in single-cell specimens....
Quantitative descriptions of animal behavior are essential to study the neural substrates cognitive and emotional processes. Analyses naturalistic behaviors often performed by hand or with expensive, inflexible commercial software. Recently, machine learning methods for markerless pose estimation enabled automated tracking freely moving animals, including in labs limited coding expertise. However, classifying specific based on data requires additional computational analyses remains a...
Despite the prevalence of superresolution (SR) microscopy, quantitative live-cell SR imaging that maintains completeness delicate structures and linearity fluorescence signals remains an uncharted territory. Structured illumination microscopy (SIM) is ideal tool for imaging. However, it suffers from out-of-focus background leads to reconstruction artifacts. Previous post hoc suppression methods are prone human bias, fail at densely labeled structures, nonlinear. Here, we propose a physical...
WE43 magnesium alloy has been considered as a promising candidate material for biodegradable coronary stents. In order to evaluate the effects of blood flow on corrosion process Mg and its alloys, behaviours cast pure extruded in Hank's solution under three different conditions, i.e. static, stirring flowing, were investigated present work. We found that exhibited much higher rate than regardless liquid flowing condition solution. Both samples lowest while promoted local with rates six times...
We introduce Airy-beam tomographic microscopy (ATM) for high-resolution, volumetric, inertia-free imaging of biological specimens. The work exploits the highly adjustable Airy trajectories in 3D space, transforming conventional telecentric wide-field scheme that requires sample or focal-plane scanning to acquire information. results present a consistent near-diffraction-limited resolution across tenfold extended depth compared microscopy. anticipate strategy not only offer promising paradigm...
Microchannels created in poly-2-hydroxyethyl methacrylate (poly(HEMA)) hydrogels have the potential to prevent dry-eye disease by facilitating tear exchange. Biosensors are further demonstrated for wearable biosensing applications.
Aversive stimuli can cause hippocampal place cells to remap their firing fields, but it is not known whether remapping plays a role in storing memories of aversive experiences. Here, we addressed this question by performing vivo calcium imaging CA1 freely behaving rats (n = 14). Rats were first trained prefer short path over long for obtaining food reward, then avoid the delivering mild footshock. Remapping was assessed comparing cell population vector similarity before acquisition versus...
The modified iterative phase retrieval algorithms developed in Part I [Guo et al., Appl. Opt.54, 4698 (2015)10.1364/AO.54.004698APOPAI1559-128X] are applied to perform known plaintext and ciphertext attacks on amplitude encoding Fourier-transform-based double random encryption (DRPE) systems. It is shown that the new can retrieve two keys (RPKs) perfectly. performances of tested by using retrieved RPKs decrypt a set different ciphertexts encrypted same RPKs. Significantly, it also DRPE...
The hybrid input-output algorithm, error reduction and combinations of both phase retrieval algorithms are applied to perform ciphertext-only attacks on linear canonical transform (LCT)-based amplitude encoding double-random-phase encryption (DRPE) systems. Special cases LCT-based DRPE systems, i.e., Fourier-transform-based, fractional-Fourier-transform-based, Fresnel-transform-based DRPE, can also be successfully attacked using the method proposed. Numerical simulations performed...
Recently, the vulnerability of linear canonical transform-based double random phase encryption system to attack has been demonstrated. To alleviate this, we present for first time, best our knowledge, a method securing two-dimensional scene using quadratic encoding operating in photon-counted imaging (PCI) regime. Position-phase-shifting digital holography is applied record photon-limited encrypted complex samples. The reconstruction wavefront involves four sparse (undersampled) dataset...