Eisuke Sakuma

ORCID: 0000-0001-6767-6257
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Connexins and lens biology
  • Hypothalamic control of reproductive hormones
  • Regulation of Appetite and Obesity
  • Hip disorders and treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Foot and Ankle Surgery
  • Shoulder Injury and Treatment
  • Orthopedic Surgery and Rehabilitation
  • Adipose Tissue and Metabolism
  • Lower Extremity Biomechanics and Pathologies
  • Heat shock proteins research
  • Biochemical effects in animals
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Spinal Dysraphism and Malformations
  • Diabetes and associated disorders
  • Diabetic Foot Ulcer Assessment and Management
  • Biochemical Analysis and Sensing Techniques
  • Neuroscience and Neuropharmacology Research
  • Pancreatic function and diabetes
  • Stress Responses and Cortisol
  • Osteoarthritis Treatment and Mechanisms
  • Sports injuries and prevention
  • Elbow and Forearm Trauma Treatment
  • Tendon Structure and Treatment
  • Orthopaedic implants and arthroplasty

Nagoya City University
2007-2022

Mizuho (Japan)
2005-2013

Japan Agency for Marine-Earth Science and Technology
2006

Tokyo University of Pharmacy and Life Sciences
2006

National Institute for Environmental Studies
2006

Caloric restriction (CR) is known to retard aging and delay functional decline as well the onset of diseases in most organisms. Ghrelin secreted from stomach response CR regulates energy metabolism. We hypothesized that ghrelin has a role protecting aging-related diseases. examined physiological mechanisms underlying system during process three mouse strains with different genetic biochemical backgrounds animal models accelerated or normal human aging. The elevated plasma concentration was...

10.1038/mp.2015.220 article EN cc-by Molecular Psychiatry 2016-02-02

We describe the pathology and treatment of flexible flat foot in children. The is seen overly usually involves hypermobility subtalar joint. It typically occurs childhood may continue to adulthood. arch develops spontaneously during first decade life most children comes within normal range observed adult feet. prescribed orthoses for patients. Lateral weight-bearing radiographs ultrasonography were helpful evaluation foot. Bleck recommended UCBL shoe insert cases if standing or lateral...

10.1016/j.jos.2018.09.018 article EN cc-by-nc-nd Journal of Orthopaedic Science 2018-10-23

Compound class specific radiocarbon analysis (CCSRA) was performed for polycyclic aromatic hydrocarbons (PAHs) associated with airborne particulate matter (APM) diameter <10 μm (PM10) and <1.1 (PM1.1) collected from a residential area of suburban Tokyo, Japan, seasonal particle-size variations were investigated. Source diagnostic isomer pair ratios indicated mixed contributions petroleum combustion biomass coal to the PAHs in APM. The Δ14C−PAHs APM, ranging −787 −514‰, dominance fossil fuel...

10.1021/es052407f article EN Environmental Science & Technology 2006-04-28

Abstract Since Rinehart and Farquhar reported the presence of agranulated cells in anterior pituitary gland 1953, functions folliculo‐stellate cell remain to be clarified. Intercellular junctions have been described monkey, rat, teleost glands, indicating existence cell‐to‐cell communication within organ. We pointed their possible role rapid dissemination information through a complex interconnecting system follicles involving gap junctions. The junctional/folliculo‐stellate cellular network...

10.1002/ar.a.20040 article EN The Anatomical Record Part A Discoveries in Molecular Cellular and Evolutionary Biology 2004-04-08

It has already been more than 50 years since the Pavlik harness was introduced in Japan, and today is widely recognized as standard initial treatment modality for developmental dysplasia of hip. We performed a multicenter nationwide questionnaire study concerning results twice 1994 2008.In 2008, we sent questionnaires to 12 institutes Japan specializing mainly pediatric orthopedics. compare these two studies discuss differences reduction rates, incidence avascular necrosis femoral epiphysis...

10.1007/s00776-013-0432-z article EN cc-by Journal of Orthopaedic Science 2013-06-28

Background: A small accessory facet with articular surface morphology is occasionally seen on the talus, bordering lateral end of sinus tarsi. This has been named anterolateral talar facet. However, few anatomical studies have addressed this Here we present precise emphasis correlation between presence and angle infero-lateral talus (talar — TILS angle). Materials methods: total 22 (11 male, 11 female) adult cadavers no known pathological conditions in talocalcaneal joints were examined...

10.5603/fm.2015.0010 article EN Folia Morphologica 2015-03-02

[Purpose] Sports activity has been shown to improve postural stability and vestibular function in healthy older adults. The hypothesis was that young adults undertaking sports will also have better compared with who do not undertake activity. purpose of this study investigate the differences between those such [Participants Methods] Thirty-nine were recruited divided into non-sports groups on basis their response a questionnaire concerning regular participation activities over past 12...

10.1589/jpts.31.53 article EN Journal of Physical Therapy Science 2019-01-01

A precise anatomical understanding of the morphology spine is indispensable for neck and low back pain therapy including rehabilitation. However, few studies have directly addressed spinal with a focus on height vertebral body discs. The aim current study was to analyze sex- age-related changes in by measuring distance between adjacent centers intervertebral disc spaces from posterior aspect cadavers using magnetic resonance imaging (MRI) measurements at cervical lumbar levels.In cadaveric...

10.2490/prm.20220011 article EN Progress in Rehabilitation Medicine 2022-01-01

Although numerous investigators in 1970s to 1980s have reported the distribution of LH-RH nerve fibers median eminence, a few been shown be present pars tuberalis. The significance finding remains elucidated, and there are studies on neurons tuberalis, especially dorsal tuberalis (DPT). Adult male Wistar-Imamichi rats were separated into two groups: one for electron microscopy other immunohistochemistry observe neurofilaments. Pituitary glands attached brain fixed by perfusion, sections...

10.1002/ar.20596 article EN The Anatomical Record 2007-10-10

Paralytic hip subluxation is a common problem in children with cerebral palsy. Although surgical procedures such as soft tissue release and osteotomy have been advocated for its prevention, the exact indications of remain unclear. We attempted to evaluate preoperative radiographic parameters identify prognostic factors retrospectively investigated 43 hips 27 palsy who had undergone surgery subluxation. evaluated age at time center-edge angle (CEA), migration percentage (MP), acetabular index...

10.1097/md.0000000000011847 article EN cc-by-nc Medicine 2018-08-01

Background: The articularis genus muscle pulls the suprapatellar pouch upwards when knee joint is extended, preventing mechanical impingement of capsule which theoretically could cause anterior pain. However, few anatomical studies have addressed this muscle. Here we present precise morphology genus. Materials and methods: A total 22 (13 male 9 female) adult cadavers with no pathological conditions in joints were examined during educational dissection at Nagoya City University Medical School...

10.5603/fm.2014.0048 article EN Folia Morphologica 2014-09-05

We investigated the effects of leptin and ciliary neurotrophic factor (CNTF) on gap junction formation between folliculo-stellate cells in anterior pituitary glands male rats. Thirty-day-old Wistar-Imamichi strain rats were castrated, 30 days later they received intraperitoneal injections either human recombinant or rat CNTF. They divided into seven groups according to injected materials: PBS as a control, 0.04, 0.2 1.0 mg/kg 0.004, 0.02, 0.1 Five from each group killed 1, 2, 3, 4 5 after...

10.1679/aohc.65.269 article EN Archives of Histology and Cytology 2002-01-01

We investigated the effects of hydrocortisone on formation gap junctions in and growth cilia folliculo-stellate cells. The male rats experimental groups were given daily intraperitoneal injections 5 mg/kg from Day 20 to 60. Five killed at ages 10, 20, 30 40 days after initiation injections, pituitary gland was removed each rat. Then, specimens prepared for observation by transmission electron microscopy. A delay between cells observed treated compared with control 30, 50. Another finding...

10.1002/1097-0185(20010201)262:2<169::aid-ar1026>3.0.co;2-z article EN The Anatomical Record 2001-01-01

We investigated the relationship between gap junction formation and sex steroids testosterone, progesterone 17β-estradiol in anterior pituitary glands of castrated male rats ovariectomized female rats. Male 30-day-old Wistar-Imamichi strain were or ovariectomized, 30 days later they subcutaneously injected with above steroids. They divided into six groups according to materials: sesame oil (control), progesterone, 17β-estradiol, testosterone 17β-eestradiol, 17β-estradiol. Five from each...

10.1679/aohc.66.229 article EN Archives of Histology and Cytology 2003-01-01
Coming Soon ...