A5056831371- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Stroke Rehabilitation and Recovery
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Blood Pressure and Hypertension Studies
- Mental Health Research Topics
- Cardiac pacing and defibrillation studies
- Neurological Disease Mechanisms and Treatments
- Chronic Disease Management Strategies
- Radiation Dose and Imaging
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Health Systems, Economic Evaluations, Quality of Life
- Traumatic Brain Injury Research
- Intracerebral and Subarachnoid Hemorrhage Research
Aalborg University
2021-2025
To examine how the lifetime risks of atrial fibrillation and complications after changed over time.
Background The incidence of atrial fibrillation (AF) shows substantial temporal trends, but the contribution birth cohort effects is unknown. These refer to relationship between year and likelihood developing AF. We aimed assess trends in cumulative diagnosed AF across cohorts disentangle age, calendar period by using age–period–cohort analyses. Methods In a Danish nationwide population-based study, 4.7 million individuals were selected at given index age (45, 55, 65 75 years) free followed...
Background: Reperfusion therapies (thrombolysis and thrombectomy) are of paramount importance for the recovery after ischemic stroke. We aimed to investigate if socioeconomic status (SES) was associated with chance receiving reperfusion therapy stroke in a country tax-funded health care. Methods: This nationwide register-based cohort study included patients registered Danish Stroke Registry between 2015 2018. SES determined by prestroke educational attainment, income level, employment...
Introduction: Rural residency has been associated with lower reperfusion treatment rates for acute ischemic stroke in many countries. We aimed to explore urban-rural differences IV thrombolysis a small country universal health care, and short transport times units. Patients methods: In this nationwide cohort study, adult patients registered the Danish Stroke Registry (DSR) between 2015 2020 were included. The exposure was defined by residence rurality. Data from DSR, Statistics Denmark,...
Concussion is a common diagnosis in emergency rooms, yet contemporary incidence and prevalence estimates are sparse rely on self-reported data. A nationwide cohort study was conducted to provide up-to-date information, covering the entire Danish population from 1999 2018. Hospital contacts with concussion diagnosis, including room visits, hospital admissions, outpatient contacts, were retrieved National Patient Registry (DNPR), rates age-standardized stratified. The 20-year defined as...
The distribution of the major modifiable risk factors for intracerebral hemorrhage (ICH) changes rapidly. These call contemporary data from large-scale population-based studies. aim present study was to examine trends in incidence, factors, and mortality ICH patients 2004 2017.In a cohort study, we calculated age- sex-standardized incidence rates (SIRs), (IRs) stratified by age sex per 100,000 person-years, profiles. We estimated absolute risk, Cox proportional hazards regression...
Abstract Background Geographical mapping of variations in the treatment and outcomes a disease is valuable tool for identifying inequity. We examined international intranational initiating oral anticoagulation (OAC) therapy clinical among patients with atrial fibrillation (AF) Nordic countries. also tracked real-world trends OAC outcomes. Methods conducted registry-based multinational cohort study OAC-naive an incident hospital diagnosis AF Denmark (N = 61,345), Sweden 124,120), Finland...
Abstract Aims Atrial fibrillation (AF) constitutes a major burden to health services, but the importance of incident AF in patients with heart failure (HF) is unclear. We examined associations between and hospital utilization HF. Methods results In nationwide matched‐cohort study HF patients, we identified diagnosed 2008 2018 Danish Heart Failure Registry ( N = 4463), compared them matched referents without 17 802). Incident was associated multivariable‐adjusted 4.8‐fold increase (95% CI...
To examine inter-national and regional variations in persistence of oral anticoagulation (OAC) therapy incidence clinical outcomes mortality, among patients with incident atrial fibrillation (AF) the Nordic countries.We conducted a registry-based multinational cohort study OAC-naïve diagnosed AF that redeemed at least one prescription OAC after Denmark (N = 25 585), Sweden 59 455), Norway 40 046) Finland 22 415). Persistence was dispensing from Day 365 first 90 days forward.Persistence 73.6%...
We aimed to investigate whether socioeconomic status (SES) was associated with functional outcome in patients ischemic stroke treated reperfusion therapy (intravenous thrombolysis and/or thrombectomy).This nationwide cohort study included reperfusion-treated ≥18 years registered the Danish Stroke Registry between 2015 and 2018. Functional determined by modified Rankin Scale score 90 days after stroke. SES defined educational attainment, family income, employment before data were available...
Incident atrial fibrillation (AF) is an adverse prognostic indicator in heart failure (HF); identifying modifiable targets may be relevant to reduce the incidence and morbidity of AF. Therefore, we examined association between quality HF care risk Using Danish Heart Failure Registry, conducted a nationwide registry-based cohort study all incident patients diagnosed 2008 2018 without history Quality was assessed by seven process performance measures, including echocardiographic examination,...
Objectives Accurate prediction of heart failure (HF) patients at high risk atrial fibrillation (AF) represents a potentially valuable tool to inform shared decision making. No validated model for AF in HF is currently available. The objective was develop clinical models 1-year AF. Methods Using the Danish Heart Failure Registry, we conducted nationwide registry-based cohort study all incident diagnosed from 2008 2018 and without history Administrative data sources provided predictors. We...
Abstract Background Older individuals with atrial fibrillation (AF) often present multiple comorbidities that might challenge their clinical management and worsen the prognosis. Identifying homogenous groups of within similar patterns health trajectories could potentially facilitate a better integrated care targeting patient-centred needs in AF management. Purpose To characterize comorbidity to explore prognostic value outcomes among older adults AF. Methods We used population-wide registry...
Prior work estimated excess death rates associated with atrial fibrillation (AF) in heart failure (HF) hazard ratios (HR). The aim was to estimate the life-years lost after newly diagnosed AF HF patients.Among patients 2008-2018 nationwide Danish Heart Failure Registry, we compared incident referents matched on age, sex, and time since HF. We marginal ratio (HR) for difference restricted mean survival times (RMST) between cases at 10 years diagnosis. adjusted age diagnosis, clinical...
Abstract Introduction Individuals affected by atrial fibrillation (AF) often present with multiple comorbidities that challenge their clinical management and worsen the prognosis. Characterizing network structure of comorbid chronic conditions in AF patients may provide insights to better tailor medical care management. Purpose To examine compare older people without AF. Methods Cross-sectional data derived from Danish National Patient Register (period 2012–2017) were examined. Patients 60+...
Aims: To estimate the life-years lost after newly-diagnosed atrial fibrillation (AF) in heart failure (HF) patients. Methods and Results: Among patients diagnosed with HF 2008-2018 nationwide Danish Heart Failure Registry, we compared incident AF (n=4,463, mean age 73.7 years, 29% women) to AF-free referents matched on age, sex, time since (n=17,792). By using G-computation, estimated marginal hazard ratio for death (HR) difference restricted survival times (RMST) at 10 years diagnosis...