- Poxvirus research and outbreaks
- HIV/AIDS Research and Interventions
- Fungal Infections and Studies
- Bacterial Infections and Vaccines
- HIV-related health complications and treatments
- Bacillus and Francisella bacterial research
- Pneumocystis jirovecii pneumonia detection and treatment
- Herpesvirus Infections and Treatments
- Amphibian and Reptile Biology
- Species Distribution and Climate Change
- HIV Research and Treatment
- Antifungal resistance and susceptibility
- Cerebrospinal fluid and hydrocephalus
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- Neonatal and Maternal Infections
- Zoonotic diseases and public health
- Syphilis Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Rabies epidemiology and control
- Plant Pathogens and Fungal Diseases
- COVID-19 and healthcare impacts
- Infectious Encephalopathies and Encephalitis
- Viral Infections and Outbreaks Research
University Health Network
2024
Toronto Western Hospital
2024
Fundação Oswaldo Cruz
2016-2023
Universidade Federal Fluminense
2020-2023
Creative Commons
2023
Ministério da Saúde
2022
Instituto Evandro Chagas
2022
Hospital Federal dos Servidores do Estado
2006
By October 30, 2022, 76,871 cases of mpox were reported worldwide, with 20,614 in Latin America. This study reports characteristics a case series suspected and confirmed at referral infectious diseases center Rio de Janeiro, Brazil.
We evaluated in-hospital mortality and outcomes incidence after hospital discharge due to COVID-19 in a Brazilian multicenter cohort.This prospective study (RECOVER-SUS, NCT04807699) included patients hospitalized public tertiary hospitals Brazil from June 2020 March 2021. Clinical assessment blood samples were performed at admission, with post-hospital remote visits. Hospitalized participants followed-up until 31, The of rehospitalization or death discharge. Kaplan-Meier curves Cox...
Objectives: This study aimed to analyze characteristics of mpox hospitalization in a Brazilian cohort, further exploring the impact HIV on mpox-related outcomes and hospitalization. Design: We conducted descriptive analysis, comparing individuals diagnosed with according status, described cases among those living HIV. Methods: was single-center, prospective cohort at major infectious diseases referral center Rio de Janeiro, Brazil, that enrolled participants older than 18 years age mpox....
Meningeal sporotrichosis is rare and occurs predominantly in immunosuppressed individuals. This retrospective study explored clinical laboratory characteristics, treatment, prognosis of patients with disseminated who underwent lumbar puncture (LP) at a Brazilian reference center from 1999 to 2020. Kaplan-Meier Cox regression models were used estimate overall survival hazard ratios. Among 57 enrolled patients, 17 had meningitis. Fifteen (88.2%) HIV infection, 6 them, neurological...
Following the 2022 global mpox outbreak, diagnoses decreased worldwide, even in settings with limited vaccine access. In 2023-2024, a new outbreak emerged Rio de Janeiro, Brazil, highlighting importance of continuous surveillance, preventive measures such as vaccination vulnerable populations, and treatment options, emphasizing equitable health technology distribution.
Purpose: In this article, the authors describe multifocal choroiditis related to disseminated sporotrichosis in patients with HIV/AIDS. Methods: We conducted a retrospective observational study of three infected HIV who presented characterized by cutaneous lesions, choroiditis, and other manifestations, including osteomyelitis involvement bone marrow, larynx, pharynx, nasal oral mucosa. Results: Five eyes HIV/AIDS showed sporotrichosis. The CD4 + counts ranged from 25 53 mm −3 . All were...
Paracoccidioidomycosis (PCM) is one of the most important systemic mycoses in Latin America and leading fungal cause mortality non-immunosuppressed individuals Brazil. However, HIV/PCM co-infection can increase clinical severity these co-infected patients. This rarely reported literature mainly because different epidemiological profiles infections. Furthermore, PCM a neglected non-notifiable disease, which may underestimate real importance this disease. The advent molecular studies on...
Objectives The characteristics of critically ill HIV‐positive patients and the causes their admission to intensive care units (ICUs) are only known through retrospective unicentric studies. This study aims fill this knowledge gap. Methods is a prospective, multicentre cohort short‐ medium‐term prognostic factors. setting consisted ICUs three tertiary referral hospitals from largest metropolitan areas in Brazil period January 2014 November 2015. In all, 161 HIV over 18 years old were...
Background Central nervous system infections (CNSI) are diseases with high morbidity and mortality, their diagnosis in the intensive care environment can be challenging. Objective : To develop validate a diagnostic model to quickly screen patients suspected CNSI using readily available clinical data. Methods Derivation cohort 783 admitted an infectious unit (ICU) Oswaldo Cruz Foundation, Rio de Janeiro RJ, Brazil, for any reason, between 01/01/2012 06/30/2019, prevalence of 97 (12.4%) cases....
Coil migration poses a significant intraprocedural risk during coil embolization in interventional neuroradiology procedures. In this technical video we describe the technique of removal errand coils using low profile Tigertriever-13 device.1 Traditional methods errant retrieval rely on use stent retrievers;2 however, these devices are usually too large to fit through smaller inner diameter 0.013–0.0165 inch coiling catheters, thus requiring upsizing materials emergency situations.3 We...
Knowing the short-term prognostic factors of critically ill HIV patients admitted to intensive care units (ICUs) in era combination antiretroviral therapy (cART) is important for adoption preventive measures and more effective treatment. To identify most significant common that determine mortality, a systematic review relevant literature was carried out. Method: An internet search conducted three databases indexing scientific articles (PubMed, Scopus, Web Science) studies investigating...
Introduction: In 2022, many countries, such as Brazil, experienced outbreaks of mpox (formerly called monkeypox) in sexually active people with multiple sexual partners. Objective: Report cases patients diagnosed Mpox. Methods: three Mpox treated at the STD Sector Universidade Federal Fluminense. Results: We report young adult who spontaneously sought our service wounds anogenital area, mouth and other parts body. These include a 28-year-old man (HIV positive) had lesions on his penis body,...
Background: By September 6, 2022, 52,997 cases of monkeypox were reported worldwide, with 8,556 in Latin America. This study reports characteristics a case series suspected and confirmed at referral infectious diseases center Rio de Janeiro, Brazil.Methods: was single-center, prospective, observational cohort that enrolled all patients between June 12 August 19, 2022. Monkeypox by PCR test. We compared non-confirmed cases, among according to HIV status using distribution tests. Kernel...
There is little information comparing the performance of community acquired central nervous system infections (CNSI) treatment by intensive care units (ICUs) specialized in infectious diseases with at other ICUs. Our objective was to reduce these gaps, creating bases for benchmarking and future case-mix classification.This a retrospective observational cohort 785 admissions 82 cases CNSI admitted ICU an important Brazilian referral center (INI) between January 2012 2019. Comparisons were...
Mulher, 45 anos, previamente hígida, foi internada por quadro de confusão mental, agitação psicomotora e crises epilépticas iniciado 3 dias após receber vacina tríplice viral. Hipótese diagnóstica inicial encefalite pós-vacinal, ácido valproico 1500 mg/dia introduzido para controle das crises. Devido a possibilidade herpética, fez uso aciclovir venoso. Durante internação realizou ressonância magnética (RM) crânio que evidenciou lesões hiperintensas em FLAIR nos centros semiovais lobo...
Apresentação do Caso Uma mulher, cisgênero, de 48 anos, enfermeira, residente Rio Janeiro e sem comorbidades, foi internada com quadro cefaleia, odinofagia, disúria dificuldade evacuação, associado a lesões umbilicadas ulceradas disseminas no tronco, membros, regiões genital anal, iniciado quatro dias antes piora progressiva. Ela referia relação sexual homem que também apresentava semelhantes, incluindo balanopostite. O exame proctológico revelou múltiplas dolorosas canal atingindo o reto...
Relato dos Casos Paciente 1: paciente do sexo masculino, de 46 anos, vivendo com o vírus da imunodeficiência humana (HIV), abandono tratamento havia 1 ano, carga viral elevada e CD4 23. Apresentou astenia febre não aferida, inúmeras lesões cutâneas umbilicadas, diâmetros variados, fundo necrótico, exsudativas, sobretudo na região anogenital, grande área coalescência úlceras menores, difícil individualização esfíncter anal. Durante primeiro atendimento, foi submetido a confecção colostomia,...