A5100726532- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Sulfur Compounds in Biology
- Advanced biosensing and bioanalysis techniques
- Analytical Chemistry and Sensors
- Advanced Fluorescence Microscopy Techniques
- Nitric Oxide and Endothelin Effects
- Erythrocyte Function and Pathophysiology
- Photochromic and Fluorescence Chemistry
- Porphyrin and Phthalocyanine Chemistry
- Lipid Membrane Structure and Behavior
- Nanoplatforms for cancer theranostics
- Electron Spin Resonance Studies
- Fungal Plant Pathogen Control
- Natural product bioactivities and synthesis
- Electrochemical Analysis and Applications
- Spectroscopy and Chemometric Analyses
- Parathyroid Disorders and Treatments
- Eicosanoids and Hypertension Pharmacology
- Weed Control and Herbicide Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Chemical Synthesis and Analysis
- Polymer Nanocomposite Synthesis and Irradiation
- Plant-derived Lignans Synthesis and Bioactivity
- Photopolymerization techniques and applications
Northwest A&F University
2025
Dalian University
2011-2022
Dalian University of Technology
2010-2022
Liaoning University
2016-2022
Sinochem Group (China)
2022
Shenyang Sinochem Agrochemicals R&D Co., Ltd. (China)
2022
Nankai University
2010
Wuhan University
2008-2010
Peking University
2007-2008
A lysosome-specific and two-photon fluorescent probe, Lyso-NINO, demonstrates high selectivity sensitivity toward NO, lower cytotoxicity, perfect lysosomal localization. With the aid of first capture NO within lysosomes macrophage cells has been achieved using both fluorescence microscopy flow cytometry.
Baseline findings from the China Dialysis Calcification Study (CDCS) revealed a high prevalence of vascular calcification (VC) among patients with end-stage kidney disease; however, data on VC progression were limited. To understand at different anatomical sites, identify risk factors for progression, and assess association cardiovascular events death receiving maintenance dialysis. This cohort study was 4-year follow-up assessment participants in CDCS, nationwide multicenter prospective...
To develop sensitive and selective CN− chemosensors, a new imidazole-functionalized polyfluorene (P1) was designed obtained conveniently, the fluorescence of which could be completely quenched by Cu2+ ions at concentration as low 0.20 ppm in diluted solutions. By utilizing much higher stability constant complex Cu2+, solution P1 recover upon addition trace anions, with detection limit down to 0.31 ppm, making novel, cyanide probe.
Abstract We have connected a borondipyrromethene (BODIPY) donor to the 5′ position of tetramethylrhodamine (TMR) acceptor form high efficiency (over 99 %) intramolecular fluorescence resonance energy transfer (FRET) cassette, BODIPY–rhodamine platform (BRP). While good spectral overlap between emission BODIPY and absorption TMR was one favorable factor, another feature this FRET system rigid short biphenyl spacer that favored efficient through‐bond transfer. More importantly, in system,...
In the orignial 1,3,5,7-tetraphenyl aza-BODIPY, replacing phenyl rings with thiophene achieved significant bathochromic shifts. One of target molecules, DPDTAB, emitting strong NIR fluorescence a quantum yield 0.46 in acetonitrile, is very competitive fluorophore.
Rhodamine derivatives and analogues have been widely used for different super-resolution imaging techniques, including photoactivated localization microscopy (PALM). Among them, rhodamine spirolactams exhibit great superiority PALM due to a desirable bright–dark contrast during the photochromic switching process. Although considerable attention has paid chemical modifications on spirolactams, on-time of switching, one key characteristics imaging, never optimized in previous developments. In...
Nitric oxide (NO) is a ubiquitous cellular messenger molecule in the cardiovascular, nervous, and immune systems. Mitochondrion main area where endogenous NO synthesized by inducible NOS enzymes mammalian cells. Thus, real-time monitoring mitochondria very meaningful for chemical biology. Although variety of fluorescent probes have been successfully developed, they are not suited detecting mitochondrial because none them can specifically localize mitochondria. Herein, Mito-Rh-NO, first...
FRET cassette-type sensors, SN-1 and SN-2, which contain two naphthalimide donors a squaraine acceptor, have been developed on the concept of switching off through removing spectral overlap by analyte-induced decompositions acceptor chromophore. SN-2 shows sensitive responses to fluoride anion cyanide both naked-eye detectable colour changes ratiometric fluorescence changes. As first example, confirms that transformation common 'turn-off' chemodosimeter into sensors can be realized...
Based on a FRET scaffold bearing BODIPY and TMR fluorophores, ratiometric fluorescent probe BRP-NO highly sensitive selective to nitric oxide was developed employed for imaging intracellular released from NOC13.
Living erythrocyte (red blood cell, RBC) membranes present rich ultrastructural and dynamic details, which require synchronous super-resolution imaging single-molecule tracking to be revealed. Yet, it poses a serious challenge achieve these dual functions in single probe, due the rigid conflicting photophysical demands of different techniques. Herein, we rationally developed far-red boron dipyrromethene membrane probe with blinking capability persistent emission, constructed microfluidic...
Rh-BMDZ with neutral p<italic>K</italic><sub>a</sub>6.9 succeeds in indicating and discriminating mitochondria lysosomes simultaneously MCF-7 cells.
Inspired by the ring-open reaction of rhodamine spriolactams as typical chemodosimeters, a general strategy is proposed to conveniently and efficiently synthesize isomerically pure 5- 6-R-tetramethylrhodamine on larger scale.
This work deals with the synthesis and photophysical laser properties of new BODIPY-rhodamine cassettes. These dyads differ in their rigid conjugated spacer group (phenyl or acetylenephenyl) linking positions (meta para). The these cassettes are controlled by formation/opening spirolactone ring, which, turn, switches off/on an energy-transfer process between chromophores. Herein, we thoroughly describe influence attached group, as well distance orientation donor-acceptor pair, on excitation...