A5102005485- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Renal and Vascular Pathologies
- Systemic Sclerosis and Related Diseases
- Atrial Fibrillation Management and Outcomes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Diabetes Management and Research
- Meningioma and schwannoma management
- SARS-CoV-2 and COVID-19 Research
- Biomedical Research and Pathophysiology
- COVID-19 Clinical Research Studies
- Acute Myocardial Infarction Research
- Diabetes Management and Education
- Gastric Cancer Management and Outcomes
- COVID-19 Impact on Reproduction
- Healthcare and Venom Research
- Parathyroid Disorders and Treatments
- Dialysis and Renal Disease Management
- Vasculitis and related conditions
- Psoriasis: Treatment and Pathogenesis
- Venous Thromboembolism Diagnosis and Management
- Vascular Malformations Diagnosis and Treatment
- Acupuncture Treatment Research Studies
Capital Medical University
2016-2025
Jiangsu Provincial Hospital of Traditional Chinese Medicine
2025
Beijing Anzhen Hospital
2016-2025
Kunming Medical University
2010-2024
Beijing Tsinghua Chang Gung Hospital
2017-2023
Tsinghua University
2017-2023
Weatherford College
2020-2021
Bioscience (China)
2021
The Affiliated Yongchuan Hospital of Chongqing Medical University
2013-2020
Chongqing Medical University
2013-2020
Baseline findings from the China Dialysis Calcification Study (CDCS) revealed a high prevalence of vascular calcification (VC) among patients with end-stage kidney disease; however, data on VC progression were limited. To understand at different anatomical sites, identify risk factors for progression, and assess association cardiovascular events death receiving maintenance dialysis. This cohort study was 4-year follow-up assessment participants in CDCS, nationwide multicenter prospective...
Summary Background and objectives The association between mortality physical activity based on self-report questionnaire in hemodialysis patients has been reported previously. However, because is a subjective assessment, evaluating true difficult. This study investigated the prognostic significance of habitual 7-year survival cohort clinically stable adequately dialyzed patients. Design, setting, participants, & measurements A total 202 Japanese outpatients who were undergoing...
Skeletal muscle wasting is common and insidious in patients who are undergoing hemodialysis. However, the association between lower extremity strength all-cause mortality remains unclear this population.The purpose of study was to investigate prognostic significance on 7-year survival a cohort were clinically stable hemodialysis.A prospective conducted.A total 190 Japanese outpatients maintenance hemodialysis 3 times per week at center followed for up 7 years. Lower evaluated using handheld...
Background Idiopathic membranous nephropathy (IMN) is the most common pathological type in adults with nephrotic syndrome. Many target antigens have been discovered. However, dual antigen-positive IMN patients are very rare, only a few such cases being briefly described various studies. There no specific study on clinicopathological and prognostic characteristics of patients, disease remain unclear. Methods Immunohistochemical staining PLA2R, THSD7A, NELL-1 was conducted kidney tissue...
The neural EGF-like 1 (NELL-1) protein is a novel antigen in primary membranous nephropathy. prevalence and clinical characteristics of NELL-1-positive nephropathy Chinese individuals with are unclear.A total 832 consecutive patients biopsy-proven were enrolled. glomerular expression phospholipase A2 receptor (PLA2R) thrombospondin type domain-containing 7A (THSD7A) was screened. Glomerular immunohistochemistry staining for NELL-1 performed 43 PLA2R- THSD7A-negative nephropathy, 31...
Randomized clinical trials (RCTs) of PCSK9 monoclonal antibody(mAb) specifically for Chinese patients have been limited. This multi-center RCT is to clarify the efficacy and safety a novel mAb, Ebronucimab, in patients. Patients diagnosed with primary hypercholesterolemia, including Heterozygous Familial Hypercholesterolemia, or mixed dyslipidemia, were categorized by ASCVD risk randomly assigned at ratio 2:1:2:1 receive Ebronucimab 450 mg matching placebo every 4 weeks (Q4W), 150 2 (Q2W)....
PURPOSE: To assess the repeatability and agreement of corneal power, astigmatism, axis location, astigmatic vector component measurements using an autokeratometer a topographer in healthy subjects. SETTING: Department Ophthalmology, Kitasato University, Kanagawa, Japan. DESIGN: Evaluation diagnostic test or technology. METHODS: Keratometric readings were obtained with ARK-700A Atlas topographer. Measurement power (flattest steepest meridians), mean components (Jackson cross-cylinders J0,...
To investigate the anatomical success rates of scleral buckling (SB) and pars plana vitrectomy (PPV) performed for rhegmatogenous retinal detachment (RRD) in a large case series to identify prognostic factors primary surgical techniques.We reviewed 542 consecutive eyes RRD this retrospective study. Follow-ups were at least six months. In each two groups, 271 examined. The main outcome measure was rate. Multivariate analysis also determine whether independent risk preoperative parameters...
To explore the efficacy of acupuncture based on "gut-brain axis" combined with sensory integration training in children autism spectrum disorder (autism) and its effect gastrointestinal symptoms. A total 96 were randomized into an observation group a control group, 48 cases each 3 dropped out. Children received training. On basis treatment therapy axis", point selection scalp was forehead five needles, i.e. bilateral Touwei (ST8), Toulinqi (GB15), Shenting (GV24) Sishencong (EX-HN1), body...
The renal protective effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been confirmed. However, SGLT2i may lead to an increase in serum creatine shortly after administration. This study explores the factors influencing this change and its impact on long-term function. We retrospectively studied patients starting treatment, classifying them into kidney function deterioration (RD) non-deterioration (non-RD) groups based three-month creatinine changes. Multivariate logistic...
Prolonged fatigue among elementary and junior high school teachers not only damages their health but also affects the quality of education. The aim this study was to determine factors working conditions associated with prolonged at public schools. We distributed a self-reported, anonymous questionnaire 3,154 (1,983 in schools, 1,171 schools) schools city Japan. They were asked assess 18 aspects using seven-point Likert scale. measured Japanese version checklist individual strength...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread rapidly worldwide. This study is the first report tolerability, safety, pharmacokinetics (PK), and immunogenicity of a recombinant human anti-SARS-CoV-2 monoclonal antibody, etesevimab (CB6, JS016, LY3832479, or LY-CoV016), in healthy adults. paper describes randomized, double-blind, placebo-controlled, phase 1 study. A total 40 participants were enrolled receive single intravenous dose either placebo one four...
Background Influenza A virus displays strong reassortment characteristics, which enable it to achieve adaptation in human infection. Surveying the and virulence of novel viruses is important prevention control an influenza pandemic. Meanwhile, studying mechanism may accelerate development anti-influenza strategies. Methodology/Principal Findings The hemagglutinin (HA) neuraminidase (NA) matching patterns two pandemic H1N1 (the 1918 current 2009 strains) a highly pathogenic avian (H5N1) were...
Membranous nephropathy (MN) is a glomerular disease mediated by autoimmune complex deposition, with approximately 30% of cases attributed to secondary causes. Among them, malignant tumors are significant cause MN. Recent advancements in the identification MN-specific antigens, such as THSD7A and NELL-1, suggest potential association tumors, yet definitive proof this relationship remains elusive. Therefore, article aims review distribution antigens patients MN caused possible role these...