A5018081934- Pulsars and Gravitational Waves Research
- Gamma-ray bursts and supernovae
- Respiratory viral infections research
- Viral Infections and Immunology Research
- Glioma Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Astrophysical Phenomena and Observations
- Pleural and Pulmonary Diseases
- Pericarditis and Cardiac Tamponade
- Pneumonia and Respiratory Infections
- Cardiac tumors and thrombi
- High-pressure geophysics and materials
- Infective Endocarditis Diagnosis and Management
- Grit, Self-Efficacy, and Motivation
- Vascular Malformations Diagnosis and Treatment
- Surgical Simulation and Training
- Acute Myocardial Infarction Research
- Spinal Hematomas and Complications
- Toxin Mechanisms and Immunotoxins
- Spinal Fractures and Fixation Techniques
- Meningioma and schwannoma management
- Autopsy Techniques and Outcomes
- Sarcoma Diagnosis and Treatment
- Problem and Project Based Learning
- Anatomy and Medical Technology
Singapore General Hospital
2015-2025
Xi'an Jiaotong University
2025
National Yang Ming Chiao Tung University
2024
Duke-NUS Medical School
2020-2022
Sixth Affiliated Hospital of Sun Yat-sen University
2022
Sun Yat-sen University
2022
SingHealth
2022
National University of Singapore
2020
University of British Columbia
2020
Duke University
2020
Abstract Epithelioid glioblastoma ( eGBM ) and pleomorphic xanthoastrocytoma PXA with anaplastically transformed foci ePXA show overlapping features. Eleven eGBMs 5 ePXAs were reviewed studied immunohistochemically. Fluorescence in situ hybridization for EGFR amplification, PTEN deletion ODZ3 was also performed, Ilumina 450 methylome analysis obtained five cases. The average age 30.9 (range 2–79) years, including pediatric cases a M : F ratio of 4.5. patients had 4 averaged 21.2 10–38) years...
Burnout is a serious issue plaguing the medical profession with potential negative consequences on patient care. symptoms are observed as early school. Based Job Demands-Resources model, this study aims to assess associations between specific job resources measured at beginning of first year school burnout occurring later in year.
Power system stability prediction leveraging deep learning has gained significant attention due to the extensive deployment of phasor measurement units. However, most existing methods focus on predicting either transient or voltage independently. In real-world scenarios, these two types instability often co-occur, necessitating distinct and coordinated control strategies. This paper presents a novel concurrent framework for using spatio-temporal embedding graph neural network (STEGNN). The...
Aim: An epidemic of hand, foot and mouth disease (HFMD) occurred in Singapore between September November 2000. During the epidemic, there were four HFMD-related deaths after another three deaths. This study sought to determine risk factors predictive death from HFMD disease. Methods: The for fatal determined by comparing clinical laboratory findings cases (n= 7) non-fatal controls 131) admitted 2000 April 2001. Enterovirus 71 positive 4) 63) also compared. Results: In total, 138 with a mean...
a finance department partnership to create portal for tax-deductible donations, and access information technology licenses volunteer management communication.These institutional links facilitated our support of systems-level needs granted administrators streamlined connection previously decentralised network.Although many student organisations operate independently their universities, members these grassroots initiatives can often be identified by common academic institution may...
Cardiac myxoma is a benign neoplasm and one of the most common types primary cardiac tumors. Synchronous other malignancies are extremely rare, only limited cases have been reported. We describe young patient with newly diagnosed locally advanced laryngeal cancer, synchronous tumor detected on staging scans. An echocardiogram showed typical appearance in left atrium. Early surgery was performed view its obstructive features post recovery uneventful. The scheduled for subsequent oncological...
Abstract: Iron smelting is one of the primary sources carbon emissions. The development low-carbon ironmaking technologies essential for iron and steel industry to realize “dual carbon” ambition. Hydrogen-based flash technology eliminates traditional pretreatment steps such as sintering, pelletizing, coking while using hydrogen a reducing agent, significantly In present work, computational fluid dynamics approach employed conduct an in-depth analysis radiative properties inside reaction...
Human metapneumovirus (HMPV) is a recently discovered pathogen that causes significant proportion of respiratory infections in young infants, the elderly and immunocompromised patients. Very little known regarding cellular signalling elicited by this virus airway epithelial cells, target HMPV infection. In study, we investigated role RNA helicases retinoic acid inducible gene-I (RIG-I) melanoma differentiation-associated gene-5 (MDA-5) as main pattern recognition receptors (PRRs) involved...
The treatment of glioblastoma multiforme (GBM) is an unmet clinical need. 5-year survival rate patients with GBM less than 3%. Temozolomide (TMZ) remains the standard first-line regimen for gliomas despite fact that more 90% recurrent do not respond to TMZ after repeated exposure. We have also independently shown many Asian-derived glioma cell lines and primary cells derived from Singaporean high-grade are indeed resistant TMZ. This issue highlights need develop new effective anti-cancer...
There is an increasing availability of digital technologies for teaching and learning human anatomy. Studies have shown that such applications allow better spatial awareness than traditional methods. These anatomy platforms offer users myriad features, as the ability to manipulate 3D models, conduct prosection, investigate anatomical regions through virtual reality, or perform knowledge tests on themselves. This study examined what faculty members' value when using students these learning.
BackgroundCurrent gene- and cell-based therapies have significant limitations which impede widespread clinical application. Taking diabetes mellitus as a paradigm, we sought to overcome these by ex vivo electrotransfer of nonviral insulin expression vector into primary hepatocytes followed immediate autologous reimplantation in preclinical model diabetes.Methods ResultsIn single 3-hour procedure, were isolated from surgically resected liver wedge, electroporated with an plasmid reimplanted...
This article was migrated. The marked as recommended. Due to the increasing number of COVID-19 cases globally, and need for critical containment, Duke-NUS Medical School, Singapore, moved all its preclinical classes online, keeping with national university guidelines. sudden move from face-to-face online learning posed several challenges school's team-based (TBL) pedagogy. In TBL, student engagement is key promote peer-to-peer learning. educational faculty found that it challenging ensure...
Abstract Context The interleukin-13 receptor alpha2 (IL13RA2), which is known to be overexpressed in glioblastoma multiforme, plays a role various cellular processes such as cell migration that may contribute tumor progression. Studies have attributed IL13RA2 invasion and metastasis cancers of the ovary, breast, pancreas, but pathological thyroid cancer still unclear. Objective This study aims evaluate expression carcinomas examine progression papillary carcinoma (PTC). Methods...
Introduction Buprenorphine is a thebaine derivative that was developed in the 1970s for pain relief. It approved substitution therapy France 1996, and USA 2002. In Singapore, sublingual buprenorphine (2 8 mg tablets) has been available since 2002 treatment of opioid addiction, under brand name Subutex. registered as prescription-only medicine, but (at time writing this paper) it not controlled drug Misuse Drugs Act (MDA), Chapter 185, Statutes Republic Singapore. also Temgesic relief severe...
Primary malignant B-cell-type dural lymphoma is a rare subtype of primary central nervous system (PCNSL).We herein report an unusual case diffuse B-cell that presents as chronic subdural haematoma without extracranial involvement.The notable aspects this include the patient's immunocompetence, short clinical history symptom onset, rapid neurological deterioration and final diagnosis high-grade PCNSL.This highlights challenges neurosurgeons face, especially in emergency setting, when disease...