A5008024258- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Hepatitis Viruses Studies and Epidemiology
- Respiratory viral infections research
- Infection Control and Ventilation
- Virus-based gene therapy research
- Congenital Anomalies and Fetal Surgery
- SARS-CoV-2 and COVID-19 Research
- Virology and Viral Diseases
- Viral Infections and Vectors
- Escherichia coli research studies
- Dental Research and COVID-19
- Antibiotic Resistance in Bacteria
- Advanced Thermodynamic Systems and Engines
- Probiotics and Fermented Foods
- SARS-CoV-2 detection and testing
- Bacteriophages and microbial interactions
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Use and Resistance
- Influenza Virus Research Studies
- Dermatological and COVID-19 studies
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Viral Infectious Diseases and Gene Expression in Insects
National Laboratory of Health, Environment and Food
2016-2024
University of Ljubljana
2012-2023
Blood Transfusion Centre of Slovenia
2016
The Slovenian Research and Innovation Agency
2016
Rega Institute for Medical Research
2009
KU Leuven
2009
SUMMARY EuroRotaNet, a laboratory network, was established in order to determine the diversity of co-circulating rotavirus strains Europe over three or more seasons from 2006/2007 and currently includes 16 countries. This report highlights tremendous European population during years surveillance since points possible origins these including genetic reassortment interspecies transmission. Furthermore, ability network identify circulating with an incidence ⩾1% allowed identification emerging...
A surveillance of human, porcine and bovine rotaviruses was carried out in Slovenia 2004 2005. Stool samples were collected from a total 406 pigs (373 asymptomatic animals), 132 cattle (126 animals) 241 humans (all with diarrhoea), tested for group using RT-PCR analysed by sequencing. The aims the study to determine incidence rotavirus infection animals, look evidence zoonotic transmission detect reassortment among rotaviruses. rates shedding 18.0 % (67/373) 4.0 (5/126), respectively....
The first European rotavirus surveillance network, EuroRotaNet, comprising 16 laboratories in 15 countries, has been established.Fecal samples from gastroenteritis cases positive for group A antigen were collected multiple countries 2005 to mid-2008 and subjected G P genotyping. Epidemiological data included age, sex, geographical location, setting, dates of onset sample collection, clinical symptoms.A total 8879 rotavirus-positive characterized: 2129 the 2005-2006 season, 4030 2006-2007...
Rotaviruses are one of the major causes diarrhea in infants and children under 5 years old, especially affecting developing countries. In natural disasters, fecal matter potable waters can mix, allowing low, yet infective, concentrations rotavirus to be present water supplies, constituting a risk for population. Any most commonly detected genotypes could originate an outbreak. The development fast sensitive method that detect broadest possible range would help with efficient diagnosis...
Bats have been identified as a natural reservoir for an increasing number of emerging zoonotic viruses, such Hendra virus, Nipah Ebola Marburg rabies and other lyssaviruses. Recently, large viruses closely related to members the genus Coronavirus associated with severe acute respiratory syndrome (SARS) detected in bat species. In this study, samples were collected from 106 live bats seven different species 27 locations Slovenia. Coronaviruses by RT-PCR 14 out 36 horseshoe (Rhinolophus...
ABSTRACT Human bocavirus is a recently described respiratory pathogen. A case of life-threatening human infection previously healthy pediatric patient described. An initial clinical presentation acute bronchiolitis developed into an extremely severe course disease characterized by pneumothorax, pneumomediastinum, and failure with pronounced air-leak syndrome.
Analysis of complete capsid sequences the emerging norovirus GII.17 Kawasaki 308 from 13 countries demonstrated that they originated a single haplotype since initial emergence in China late 2014. Global spread sublineage SL2 was identified. A new SL3 emerged 2016.
ABSTRACT Mammalian orthoreoviruses (MRVs) are known to cause mild enteric and respiratory infections in humans. They widespread infect a broad spectrum of mammals. We report here the first case an MRV detected child with acute gastroenteritis, which showed highest similarity reported recently European bats. An examination stool sample from was negative for most common viral bacterial pathogens. Reovirus particles were identified by electron microscopic both suspension cell culture...
Escherichia coli is an important commensal of our gut, however, many pathogenic strains exist, causing various severe infections in the gut or beyond. Due to several antibiotic resistance patterns E. coli, research alternative treatments adjuvant therapy important. One these use probiotics as antagonistic agents against coli. Most published studies investigate only one strain and single-strain probiotics. The objectives this study were evaluate activity selected multi-strain probiotic...
Human coronaviruses (HCoVs) are associated with a variety of clinical presentations in children, but their role disease remains uncertain. The objective our prospective study was to investigate HCoVs associations various hospitalized children up 6 years age. Children acute bronchiolitis (AB), gastroenteritis (AGE), or febrile seizures (FS), and admitted for elective surgical procedures (healthy controls) were included the study. In patients AB, AGE, FS, nasopharyngeal (NP) swab blood sample...
Antimicrobial resistance of Escherichia coli is a growing problem in both developed and developing countries. This study aimed to investigate the phenotypic antimicrobial E. isolates (n = 260) isolated from stool specimen patients attending public health facilities Addis Ababa Hossana. also characterize phenotypically confirmed extended-spectrum beta-lactamase (ESBL)-producing 22) using whole-genome sequencing. Resistance 18 different antimicrobials was assessed disc diffusion method...
Human coronaviruses (HCoVs) are a well-known cause of respiratory infections but their role in gastrointestinal is unclear. The objective our study was to assess the significance HCoVs etiology acute gastroenteritis (AGE) children <6 years age. Stool samples and nasopharyngeal (NP) swabs collected from 260 hospitalized for AGE (160 also had symptoms) 157 otherwise healthy control admitted elective surgery were tested presence four using real time RT-PCR. Registered at ClinicalTrials.gov...
A renewed interest in mammalian orthoreoviruses (MRVs) has emerged since new viruses related to bat MRV type 3, detected Europe, were identified humans and pigs with gastroenteritis. This study reports the isolation characterization of a novel reassortant from lesser horseshoe (Rhinolophus hipposideros). The isolate, here designated BatMRV1-IT2011, was first by electron microscopy confirmed using PCR virus-neutralization tests. full genome sequence obtained next-generation sequencing....
Abstract A rotavirus surveillance study was undertaken in Slovenia from December 2005 to March 2006. Stool samples 114 children hospitalized with acute viral gastroenteritis were collected two main Slovenian hospitals. These confirmed rotavirus‐positive selected for a G and P genotype prevalence study. Six untypable strains of further analyzed sequencing the VP7, VP8*, NSP4 genes. The findings that G1 most prevalent, found 72 (63.2%), followed by G9 26 (22.8%), G4 10 (8.8%), G3 2 (1.7%). All...
Paediatric acute gastroenteritis is a global public health problem. Comprehensive laboratory investigation for viral, bacterial and parasitic agents helpful improving management of in care settings monitoring controlling the spread these infections. Our study aimed to investigate role various pathogens infantile diarrhoea Bulgaria outside classical winter epidemics rotavirus norovirus. Stool samples from 115 hospitalized children aged 0-3 years collected during summer months were tested...