Donatella Scaglione
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- COVID-19 and healthcare impacts
- Head and Neck Cancer Studies
- Metastasis and carcinoma case studies
- Growth Hormone and Insulin-like Growth Factors
- Trauma and Emergency Care Studies
- Esophageal and GI Pathology
- Salivary Gland Tumors Diagnosis and Treatment
- Enhanced Recovery After Surgery
- Breastfeeding Practices and Influences
- Genetic factors in colorectal cancer
- Diverticular Disease and Complications
- Ear and Head Tumors
- Hospital Admissions and Outcomes
- Interpreting and Communication in Healthcare
- Appendicitis Diagnosis and Management
- Colorectal Cancer Surgical Treatments
- Autoimmune and Inflammatory Disorders
- Cancer Genomics and Diagnostics
- Head and Neck Anomalies
- Thyroid and Parathyroid Surgery
- Hernia repair and management
- Colorectal Cancer Screening and Detection
- Fibroblast Growth Factor Research
Data Management (Italy)
2021-2022
European Institute of Oncology
2020-2022
Ospedale Martini
2013-2021
University of Turin
1997
Abstract Background It is still unclear whether D2 lymphadenectomy improves the survival of patients with gastric cancer and should therefore be performed routinely or selectively. The aim this multicentre randomized trial was to compare D1 in treatment cancer. Methods Between June 1998 December 2006, adenocarcinoma were assigned randomly either gastrectomy. Intraoperative randomization implemented centrally by telephone. Primary outcome overall survival; secondary endpoints disease-specific...
The SARS-CoV-2 (COVID-19) pandemic is having a large effect on the management of cancer patients. This study reports approach and outcomes patients receiving radical surgery with curative intent between March September 2020 (in comparison to 2019) in European Institute Oncology, IRCCS (IEO) Milan South East London Cancer Alliance (SELCA). Both institutions implemented COVID-19 minimal pathway where were required self-isolate prior admission swabbed for within 72 h surgery. Positive had...
Objective The prognostic role of age among patients affected by Oral Tongue Squamous Cell Carcinoma (OTSCC) is a topic debate. Recent cohort studies have found that diagnosed at 40 years or younger better prognosis. aim this study was to clarify whether an independent factor and discuss heterogeneity outcomes stage treatments in different groups. Methods We performed on 577 consecutive primary tongue cancer treated with surgery adjuvant therapy according stage, European Institute Oncology,...
This study aimed to evaluate the performance of 2017 8th TNM edition and latest update in 2020 compared 7th a large cohort patients affected by oral tongue squamous cell carcinoma (OTSCC), considering all stages.The involved 300 OTSCC treated with surgery. All cases were classified according 7th, (2017), updated (October 2020),. Patients grouped based on shift tumour (T) category, lymph nodal (N) category final pathological stage. Overall survival (OS) disease-free (DFS) calculated...
Abstract Evidence against the use of prophylactic drain after gastrectomy are increasing and ERAS guidelines suggest benefit avoidance. Nevertheless, it is unclear whether this practice still widespread. We conducted a survey among Italian surgeons through Gastric Cancer Research Group Polispecialistic Society Young Surgeons, aiming to understand current drain. A 28-item questionnaire-based was developed analyze individual opinion about gastrectomy. Groups based on age, experience unit...
The incidence of papillary thyroid carcinoma, which accounts for 80-90% all cancers, has recently been increasing. current study aimed to compare the oncological and functional outcomes total thyroidectomy (TT) lobectomy (TL). To this end, a retrospective single-centre cohort involving tertiary care institution was conducted. Data regarding demographics, clinicopathology postoperative complications from 586 patients with cancer treated in single were collected. Cox proportional-hazards...
Abstract Background Several reports demonstrated a strong association between the level of adherence to protocol and improved clinical outcomes after surgery. However, it is difficult obtain full into practice has still not been identified threshold beyond which functional results can be reached. Methods The ERCOLE (ERas COLorectal Endoscopic surgery) study was as cohort, prospective, multi-centre national evaluating ERAS items minimally invasive colorectal primary endpoint associate...
More than 100 different mutations in the adenomatous polyposis coli (APC) gene have been identified; virtually all lead to production of a truncated protein. Clinical details patients with missense undoubtedly cosegregating disease not reported and may be relevant understanding APC protein function.In one family familial (FAP) was analyzed by SSCP sequencing aberrant band.A mutation exon 15 at nucleotide 4921 segregating observed. This predicts tryptophan instead an arginine amino acid 1641...