A5017237200- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Environmental Toxicology and Ecotoxicology
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Surgical Treatments
- Renal cell carcinoma treatment
- Toxic Organic Pollutants Impact
- Reproductive biology and impacts on aquatic species
- Pharmaceutical and Antibiotic Environmental Impacts
- Effects and risks of endocrine disrupting chemicals
- Viral-associated cancers and disorders
- Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Advanced Radiotherapy Techniques
- Colorectal and Anal Carcinomas
- Metastasis and carcinoma case studies
- Cancer Treatment and Pharmacology
Chiesi (Italy)
2025
Humanitas Castelli
2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2024
Humanitas University
2015-2024
Humanitas Gavazzeni
2022-2024
IRCCS Humanitas Research Hospital
2014-2023
Cambridge University Hospitals NHS Foundation Trust
2023
University of Milan
2006-2022
Ospedale San Paolo
2019-2022
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2021
To evaluate the "learning curve" effect on feasibility and reproducibility of laparoscopic liver resection (LLR).LLR is currently limited to few centers procedures. Its still debated.: Patients undergoing LLR between 1996 2008 were included. Indications type hepatectomies compared with those open resections performed in same period, considering 3 periods (1996-1999, 2000-2003, 2004-2008). LLRs divided into equal groups 58 cases technical data outcomes compared. Risk-adjusted Cumulative Sum...
Abstract Background It is still unclear whether D2 lymphadenectomy improves the survival of patients with gastric cancer and should therefore be performed routinely or selectively. The aim this multicentre randomized trial was to compare D1 in treatment cancer. Methods Between June 1998 December 2006, adenocarcinoma were assigned randomly either gastrectomy. Intraoperative randomization implemented centrally by telephone. Primary outcome overall survival; secondary endpoints disease-specific...
To determine the prognostic impact of tumor location in gallbladder cancer.Depth is a strong predictor survival after curative resection cancer. However, has unique anatomical relationship with liver, and clinical significance remains unclear.For 437 patients cancer who underwent at 4 international institutions, clinicopathologic characteristics their association were analyzed. Tumor was defined as "hepatic side" or "peritoneal side," evaluated.Among 252 T2 disease, tumors on hepatic side...
We investigated the clinical significance of a vascular growth pattern hepatocellular carcinoma (HCC), vessels that encapsulate tumor clusters (VETC), previously linked to HCC metastatic dissemination. VETC was assessed in large multi‐institutional cohort 541 resected HCCs from Italy, Korea and Japan, matched against full spectrum pathological variables. The phenotype (defined as ≥ 55% area by CD34 immunostaining) easily reproducible reliably detectable whole sections small‐sized tissues...
<h3>Hypothesis</h3> The knowledge of risk factors for bile leakage after liver resection could reduce its incidence. <h3>Design</h3> Retrospective study. <h3>Setting</h3> Tertiary care referral center. <h3>Patients</h3> study included 610 patients who underwent from January 1, 1989, through 31, 2003. <h3>Interventions</h3> Liver resections without biliary anastomoses. <h3>Main Outcome Measures</h3> Bile incidence and correlation to preoperative intraoperative patient characteristics....
We analyzed the impact of chemotherapy-related liver injuries (CALI), pathological tumor regression grade (TRG), and micrometastases on long-term prognosis in patients undergoing resection for colorectal metastases after preoperative chemotherapy.CALI worsen short-term outcomes resection, but their is unknown. Recently, a prognostic role TRG has been suggested. Micrometastases (microscopic vascular or biliary invasion) are reduced by chemotherapy, survival unclear.Patients between 1998 2011...
The liver-first approach in patients with synchronous colorectal liver metastases (CRLM) has gained wide consensus but its role is still to be clarified. We aimed elucidate the outcome of and identify who benefit at most from this approach.Patients CRLM included LiverMetSurvey registry between 2000 2017 were considered. Three strategies analyzed, i.e. approach, resection followed by (primary-first), simultaneous resection, three groups solitary metastasis, multiple unilobar CRLM, bilobar...
To analyze the impact of COVID-19 emergency on elective oncological surgical activity in Italy.COVID-19 shocked national health systems, subtracting resources from treatment other diseases. Its oncology is still to elucidate.A 56-question survey regarding Italy during was sent referral centers for hepato-bilio-pancreatic, colorectal, esophago-gastric, and sarcoma/soft-tissue tumors. The portrays situation 5 weeks after first case secondary transmission Italy.In total, 54 Units 36 Hospitals...