A5101501204- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Immunotherapy and Immune Responses
- Mitochondrial Function and Pathology
- CAR-T cell therapy research
- Metabolomics and Mass Spectrometry Studies
- RNA modifications and cancer
- Physiological and biochemical adaptations
- Radiomics and Machine Learning in Medical Imaging
- Computational Drug Discovery Methods
- Cancer Immunotherapy and Biomarkers
- Receptor Mechanisms and Signaling
- Biochemical and Molecular Research
- Sarcoma Diagnosis and Treatment
- Cytokine Signaling Pathways and Interactions
- Amino Acid Enzymes and Metabolism
- Advanced X-ray and CT Imaging
Union Hospital
2025
Huazhong University of Science and Technology
2025
Fudan University
2016-2018
Huashan Hospital
2017-2018
Background Noninvasive detection of isocitrate dehydrogenase 1 mutation (IDH1(+)) and loss nuclear alpha thalassemia/mental retardation syndrome X‐linked expression ((ATRX(–)) are clinically meaningful for molecular stratification low‐grade gliomas (LGGs). Purpose To study a radiomic approach based on multiparametric MR noninvasively determining status IDH1(+) ATRX(–) in patients with LGG. Study Type Retrospective, radiomics. Population Fifty‐seven LGG ( n = 36 19 17 ATRX(+) patients)...
Abstract Anti‐glioma immunotherapy is highly challenging, largely due to poor immune infiltration and restricted delivery, resulting in patient prognosis. Recent studies suggest that mature tertiary lymphoid structures (mTLSs) promote cell into solid tumors, associated with enhanced response better However, the formation visualization of mTLSs becomes extremely difficult from lack tissue microenvironment brain parenchyma. Herein, theranostic nanoprobes consisting FITC‐HFe₃O₄@Gd (MRI/FI...
Abstract Adoptive T lymphocyte immunotherapy is one of the most promising methods to treat residual lesions after glioma surgery. However, fate adoptively transferred T‐cells in vivo unclear, hampering understanding this emerging therapy. Thus, it highly desirable develop noninvasive and quantitative tracking these for better identification migratory provide objective evaluation outcomes adoptive T‐cell targeting glioma. In work, ultrasmall 1 MR‐based nanoprobes, NaGdF 4 ‐TAT, as molecular...
The diagnosis of a tumor depends on accurate identification the target area for biopsy. However, heterogeneity and inability conventional structural data identifying most malignant areas can reduce this accuracy.To evaluate feasibility practicality magnetic resonance spectroscopy (MRS)- arterial spin labeling (ASL)-guided MRI navigation needle biopsy intracranial tumors.Thirty patients with tumors who underwent intraoperative stereotactic were retrospectively analyzed. Contrast-enhanced...
Background Time-resolved angiography with stochastic trajectories (TWIST) sequence makes considerable progress in temporal and spatial resolution, which presents high potential evaluation of vascular diseases. Purpose To assess magnetic resonance imaging (MRI) using TWIST MR (MRA) the assessment invasion for bone soft-tissue tumors comparison to computed tomography (CTA) as reference standard. Material Methods Thirty-three patients lower extremity musculoskeletal were imaged conventional...