Hao Li

ORCID: 0000-0001-6942-1557
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About
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Research Areas
  • Biochemical Analysis and Sensing Techniques
  • Protein Hydrolysis and Bioactive Peptides
  • Fuel Cells and Related Materials
  • Olfactory and Sensory Function Studies
  • Advanced Chemical Sensor Technologies
  • Calpain Protease Function and Regulation
  • Thyroid Disorders and Treatments
  • Mycotoxins in Agriculture and Food
  • Insect Utilization and Effects
  • Maternal and fetal healthcare
  • Electrocatalysts for Energy Conversion
  • Photosynthetic Processes and Mechanisms
  • Plant biochemistry and biosynthesis
  • Maternal and Perinatal Health Interventions
  • Electrochemical Analysis and Applications
  • Tree Root and Stability Studies
  • Lipid metabolism and disorders
  • Metal-Catalyzed Oxygenation Mechanisms
  • Non-Invasive Vital Sign Monitoring
  • Maritime Navigation and Safety
  • Fungal and yeast genetics research
  • Phytochemicals and Antioxidant Activities
  • Microbial bioremediation and biosurfactants
  • Conducting polymers and applications
  • Food Supply Chain Traceability

Central South University of Forestry and Technology
2025

Wuhan University of Technology
2011-2025

Beijing Forestry University
2025

Huazhong University of Science and Technology
2006-2024

Ocean University of China
2024

Henan University of Technology
2024

Hubei University
2022-2023

Fujian Medical University
2023

Inner Mongolia University of Science and Technology
2023

Academy of Medical Sciences
2021

In the present study we purified and identified peptides from broccoli protein hydrolysates evaluated their angiotensin-converting enzyme (ACE) inhibitory activity in vitro hypotensive effect vivo. Three ACE were isolated as IPPAYTK, LVLPGELAK, TFQGPPHGIQVER, IC50 values 23.5, 184.0, 3.4 μM, respectively. We then investigated of gastrointestinal digestion on activity. detected almost two times peptide LVLPGELAK following simulated than prior to digestion. LVLPGE LAK, novel exhibiting high...

10.1021/acs.jafc.9b01137 article EN Journal of Agricultural and Food Chemistry 2019-06-03

Umami peptides can help reduce the salt content in foods while still maintaining a savory taste. Few studies have reported bioactivity of umami after consumption. We studied bioactivities 12 gastrointestinal digestion. Three exhibited angiotensin I-converting enzyme (ACE) inhibitory and antioxidant activity Six novel were identified from digestion solutions by HPLC-MS/MS. Among them, CC, CCNK, HCHT had both ACE (IC50 values 9.81, 9.00, 114.99 μM, respectively) (strong...

10.1021/acs.jafc.0c02797 article EN Journal of Agricultural and Food Chemistry 2020-07-14

Geranylgeranyl diphosphate synthase (GGPPS) is the crucial bottleneck in carotenoid biosynthesis. However, low activity limits broad application of GGPPS. In this study, OsGGPPS1 rice was engineered based on ancestral sequence reconstruction (ASR) and semirational design to improve catalytic performances existing The better mutant A22R/A26P with improved enzyme generated ASR. Additionally, mutants as V162A/M218S/F227Y designed using a design. combinatorial assembly d-OsGGPPS1...

10.1021/acs.jafc.4c05029 article EN Journal of Agricultural and Food Chemistry 2024-08-13

Woody plants have received considerable attention for the phytoremediation of heavy metal-contaminated soil. This study aimed to investigate changes in antioxidant enzyme activity, macroelement uptake and microstructure woody plant Robinia pseudoacacia (black locust) cadmium (Cd) lead (Pb) co-contaminated soil based on dynamic sampling. The results show that black locust demonstrates strong tolerance Cd Pb After 30-120 days cultivation, activities superoxide dismutase, peroxidase (potassium...

10.1093/treephys/tpaf015 article EN Tree Physiology 2025-02-02

Understanding the complex mechanisms underlying sex differentiation in dioecious plants is fundamental to elucidating plant reproductive strategies and their adaptive responses environmental stresses. Pistacia chinensis, previously considered a strictly species, has been found exhibit monoecy, with closely linked stress during floral development. However, molecular remain poorly understood. This study explores influence of on focus heat shock proteins (Hsps). Biochemical analyses revealed...

10.3390/f16030395 article EN Forests 2025-02-23

The unstructured power outputs from thermoelectric generator (TEG) systems have precipitated the advancement of maximum point tracking (MPPT) methods toward more intelligent solutions. This article concentrates on centralized TEG which work during nonuniform distribution temperature cases and introduce hunter‐prey optimization algorithm with multimode updating (MMUHPO). Existing MPPT based metaheuristic algorithms pay attention to improving speed, efficiency, oscillation, call frequency....

10.1002/ente.202402070 article EN Energy Technology 2025-03-31

Abstract The biosynthesis of neurotoxin aetokthonotoxin (AETX) that features a unique structure pentabrominated biindole nitrile involves first-of-its-kind synthase termed AetD, an enzyme shares very low sequence identity to known structures and catalyzes unprecedented mechanism. In this study, we resolve the crystal AetD in complex with substrate 5,7-di-Br-L-Trp. adopts heme oxygenase like fold forms hydrophobic cavity within helical bundle accommodate indole moiety. A diiron cluster...

10.1038/s41467-023-43285-0 article EN cc-by Nature Communications 2023-11-16

Vascular endothelial hyperpermeability is one of the manifestations dysfunction. Resveratrol (Res) considered to be beneficial in protecting function. However, currently, exact protective effect and involved mechanisms Res on dysfunction-hyperpermeability have not been completely clarified. The aim present study investigate effects amelioration role caveolin-1 (Cav-1)/endothelial nitric oxide synthase (eNOS) pathway. Adult male Wistar rats were treated with a normal or high-fat/sucrose diet...

10.1371/journal.pone.0113716 article EN cc-by PLoS ONE 2014-11-24

Calpain activation contributes to hyperglycemia-induced endothelial dysfunction and apoptosis. This study was designed investigate the role of calpain inhibition in improving diabetic erectile (ED) mice. Thirty-eight-week-old male C57BL/6J mice were divided into three groups: (1) nondiabetic control group, (2) + vehicle (3) MDL28170 (an inhibitor calpain) group. Type 1 diabetes induced by intraperitoneal injection streptozotocin at 60 mg kg−1 body weight for 5 consecutive days. Thirteen...

10.4103/aja.aja_63_17 article EN cc-by-nc-sa Asian Journal of Andrology 2018-01-01

Abstract Background The mechanism underlying maternal fever and prolonged labor progression associated with neuraxial analgesia (NA) remains elusive, raising concerns among certain pregnant women regarding the application of NA during vaginal delivery. This study aimed to investigate impact early late on neonatal outcomes in multiparous women. Methods retrospective collected data from 1119 singleton pregnancies, full term live births at our delivery center between August 1st, 2021 July 31st,...

10.1186/s12871-023-02395-4 article EN cc-by BMC Anesthesiology 2024-01-02

Excessive iodine induces thyroid dysfunction. However, the effect of excessive exposure on maternal–fetal hormone metabolism and expression genes involved in differentiation, growth development is poorly understood. Since a receptor response element was found Hoxc8 promoter region, possibly regulated by firstly investigated. In present study, Balb/C mice were given different doses form potassium iodate (KIO 3 ) at levels 0 (sterile water), 1·5, 3·0, 6·0, 12·0 24·0 μg/ml drinking water for 4...

10.1017/s0007114507691909 article EN British Journal Of Nutrition 2007-04-24

Recent progress in atomic-scale TEM characterization of structural heterogeny 2D TMD layers is overviewed. The prospects visualization techniques are assessed toward identification and manipulation defects heterointerfaces.

10.1039/d1ma01013a article EN cc-by-nc Materials Advances 2021-12-13
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