A5042400183- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Neutropenia and Cancer Infections
- Infections and bacterial resistance
- Vibrio bacteria research studies
- COVID-19 Clinical Research Studies
- Infective Endocarditis Diagnosis and Management
- Cystic Fibrosis Research Advances
- Infectious Diseases and Tuberculosis
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Salmonella and Campylobacter epidemiology
- COVID-19 and Mental Health
- Actinomycetales infections and treatment
- Streptococcal Infections and Treatments
- Infectious Diseases and Mycology
- Clinical Reasoning and Diagnostic Skills
- Enterobacteriaceae and Cronobacter Research
- vaccines and immunoinformatics approaches
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Vasculitis and related conditions
- Cassava research and cyanide
- Orthopedic Infections and Treatments
- Diphtheria, Corynebacterium, and Tetanus
Nagoya City University
2024-2025
Aichi Cancer Center
2021-2025
Nagoya Medical Center
2025
Shizuoka Cancer Center
2024
Tokyo Medical University
2023
Carbapenem-resistant Gram-negative bacilli (CRGNB), especially Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii, are critical pathogens associated with excess morbidity mortality. To elucidate their molecular epidemiology clinical outcomes in Japan, patients CRGNB were enrolled the MDR organisms research network (MDRnet) consisting of eight tertiary care facilities. Between 2019 2022, 246 unique carbapenem-resistant Enterobacterales (CRE), P. (CRPA) A. baumannii (CRAB)...
Abstract The direct impact of antimicrobial stewardship programs (ASP) and infectious disease (ID) consultations on patients' clinical diagnoses remains unknown. We assessed their influence improving the diagnostic accuracy blood culture-positive inpatients at a Japanese cancer center. Our single-center, retrospective observational study was conducted from April 1, 2018 to March 31, 2022 evaluate two phases: pre-intervention (notification antimicrobials by infection control team)...
In cancer patients, appropriate diagnosis and management of infection are frequently challenging owing to subtle or atypical presentation. We investigated the effectiveness infectious disease (ID) consultations Antimicrobial Stewardship Program (ASP) in a Japanese center. This 36-month-period, single-institution, interrupted time series analysis was retrospectively conducted during April 1, 2018–March 31, 2021, evaluate two-phase intervention: Phase 1 (notification antimicrobials by control...
Abstract Background Pseudomonas nitroreducens is a non-fermenting, gram-negative, rod-shaped bacterium commonly inhabiting soil, particularly soil contaminated with oil brine. To our knowledge, no cases of human infection P. have been previously reported. Here, we present the first documented case cholangitis caused by in patient bacteremia. Case presentation A 46-year-old Japanese man an advanced pancreatic neuroendocrine tumor was hospitalized fever and chills. Four days before admission,...
Abstract Background Patients with cancer are particularly susceptible to developing drug-resistant organisms due the high frequency of infections during treatment and use broad-spectrum antimicrobial agents. Therefore, patients ideal candidates for an stewardship program (ASP); however, no established ASPs specifically target these patients. In this study, we evaluated effect a 46-month ASP intervention infectious diseases consultation using unique quality measure. Methods Our single-center,...
Abstract Background Schizophyllum commune is a basidiomycete that lives in the environment and can cause infections, mainly those of respiratory system. Although S. increasingly reported as allergic bronchopulmonary mycosis sinusitis, cases fungal ball formation are extremely uncommon. Identification difficult using routine mycological diagnostic methods, clinically suspicious cases, internal transcribed spacer sequencing should be used for diagnosis. Here, we report first case lung cancer...
Abstract Background Campylobacter rectus is a gram-negative rod, and Parvimonas micra gram-positive coccus, both of which are oral anaerobes that cause chronic periodontitis. Chronic periodontitis can bacteremia systemic diseases, including osteomyelitis. Hematogenous osteomyelitis caused by anaerobic bacteria uncommon, to date, there have been no reports mixed with C. P. . Here, we report the first case femur Case presentation A 75-year-old man periodontitis, hyperuricemia, benign prostatic...
Christensenella hongkongensis is an obligately anaerobic, catalase-positive, motile, non-sporulating, gram-positive coccobacillus. Human infections are rare and have not been previously reported in Japan. Herein, we report the first case of perforated peritonitis with C. bacteremia Japan.A 61-year-old Japanese man advanced colorectal adenocarcinoma presented fever abdominal pain. Abdominal computed tomography revealed a low-density area thinning sigmoid colon wall air outside intestinal...
Oral third-generation cephalosporins (3GCs) are not recommended for use owing to their low bioavailability and the risk of emergence resistant microorganisms with overuse. A standardized effective method reducing is lacking. Here, in a 60-month, single-institution, interrupted time-series analysis, which was retrospectively conducted between April 1, 2017, March 31, 2022, we evaluated effectiveness four-phase intervention reduce 3GCs patients at cancer center: Phase 1 (pre-intervention), 2...
There is no clear consensus regarding the optimal isolation duration for immunocompromised patients with coronavirus disease 2019 (COVID-19). Therefore, we conducted a questionnaire survey at eight Japanese cancer centers to investigate practices of infectious specialists COVID-19 inpatients cancer. For asymptomatic severely ill without severe immunodeficiency, four reported least 10 days testing, and two 20 days. Two incorporated polymerase chain reaction (PCR) as criterion terminating...
The clinical significance of enterococci in intra-abdominal infections, particularly those caused by multiple organisms, remains unclear. There are no definitive guidelines regarding the use empiric therapy with antimicrobial agents targeting enterococci. In this study, we evaluated impact initial administration anti-enterococcal on treatment infections patients cancer whom were isolated from ascitic fluid cultures. This retrospective study was conducted at Shizuoka Cancer Center between...
Abstract Background Pandoraea species are multidrug-resistant glucose-nonfermenting gram-negative bacilli that usually isolated from patients with cystic fibrosis (CF) and water soil. Reports of diseases, including bloodstream infections, caused by spp. in non-CF rare, the clinical microbiological characteristics unclear. The identification Pandorea is limited conventional methods may be misidentified as other owing to overlapping biochemical profiles. Here, we report first case obstructive...