A5026363329- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- Herpesvirus Infections and Treatments
- Poxvirus research and outbreaks
- Antibiotic Resistance in Bacteria
- COVID-19 Impact on Reproduction
- Infection Control and Ventilation
- Bacillus and Francisella bacterial research
- Sepsis Diagnosis and Treatment
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- COVID-19 diagnosis using AI
- Antimicrobial Resistance in Staphylococcus
- Healthcare professionals’ stress and burnout
- Respiratory Support and Mechanisms
- Linguistic research and analysis
- Thermal Regulation in Medicine
- Pneumonia and Respiratory Infections
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Temporomandibular Joint Disorders
National Center for Global Health and Medicine
2018-2025
Center for Global Health
2018-2024
Nippon Medical School Musashi Kosugi Hospital
2024
Tohoku University
1957-2022
University of Pennsylvania
2022
Australian National University
2022
Inpex (Japan)
2021
Suzuki (Japan)
2021
Yokohama City University
2020
National Institute of Infectious Diseases
2020
There is limited understanding of the characteristics patients with coronavirus disease 2019 (COVID-19) requiring hospitalization in Japan.
Abstract Some patients who recover from coronavirus disease 2019 (COVID-19) have prolonged symptoms such as dyspnea, fatigue, cough, and dysosmia for longer than 120 days after symptom onset. In addition, some recovered COVID-19 reported hair loss a few months the onset of disease. Alopecia is late-onset COVID-19. The cause alopecia unknown; however, androgenic telogen effluvium are possible causes.
Objectives To investigate the risk factors contributing to severity on admission. Additionally, of worst and fatality were studied. Moreover, compared based three points: early severity, fatality. Design An observational cohort study using data entered in a Japan nationwide COVID-19 inpatient registry, COVIREGI-JP. Setting As 28 September 2020, 10480 cases from 802 facilities have been registered. Participating cover wide range hospitals where patients with are admitted Japan. Participants...
Mastication has been suggested to increase neuronal activities in various regions of the human brain. However, because technical difficulties, fine anatomical and physiological linked mastication have not fully elucidated. Using functional magnetic resonance imaging during cycles rhythmic gum-chewing no chewing, we therefore examined interaction between chewing brain regional activity 17 subjects (aged 20-31 years). In all subjects, resulted a bilateral blood oxygenation level-dependent...
Numerous prospective studies have investigated the association between number of remaining teeth and dementia or cognitive decline. However, no agreement has emerged on tooth loss impairment, possibly due to past differing in target groups methodologies. We aimed investigate loss, as evaluated through clinical oral examinations, development impairment community-dwelling older adults while considering baseline function.This 4-year cohort study followed 140 (69.3% female) without aged ≥65...
Before widespread coronavirus disease (COVID-19) vaccinations, Japan experienced three COVID-19 epidemic waves. This study aimed to evaluate the characteristics of hospitalised patients and reveal temporal changes.
The aim of this study was to investigate the epidemiology post-COVID conditions beyond 12 months and identify factors associated with persistence each condition.This a cross-sectional questionnaire-based survey.We conducted survey among patients who had recovered from COVID-19 visited our institute between February 2020 November 2021. Demographic clinical data regarding presence duration were obtained. We identified using multivariable linear regression analyses.Of 1148 surveyed patients,...
Age-related changes in mastication-induced brain neuronal activity have been suggested. However, humans, little is known about the anatomical regions involved. Using fMRI during cycles of rhythmic gum-chewing and no chewing, we examined effect aging on regional chewing young adult (19–26 yrs), middle-aged (42–55 aged (65–73 yrs) healthy humans. In all subjects, resulted a bilateral increase BOLD signals sensorimotor cortex, cerebellum, thalamus, supplementary motor area, insula, unilateral...
<b><i>Introduction:</i></b> Old age is an independent risk factor (RF) for severe COVID-19; evidence clinico-epidemiological characteristics among elderly COVID-19 patients scarce. We aimed to analyze clinical and epidemiological comorbidities associated with inpatients in age-stratified populations of cohort. <b><i>Methods:</i></b> conducted a retrospective cohort study, using nationwide registry data hospitalized before October 31, 2020...
Carbapenem-resistant Gram-negative bacilli (CRGNB), especially Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii, are critical pathogens associated with excess morbidity mortality. To elucidate their molecular epidemiology clinical outcomes in Japan, patients CRGNB were enrolled the MDR organisms research network (MDRnet) consisting of eight tertiary care facilities. Between 2019 2022, 246 unique carbapenem-resistant Enterobacterales (CRE), P. (CRPA) A. baumannii (CRAB)...
Background Inappropriate antibiotic prescribing is a cause of antimicrobial resistance. Acute Respiratory Tract Infections (ARTI) are common diseases for those antibiotics most likely prescribed in outpatient setting. Objectives To clarify factors associated with non-bacterial acute respiratory tract infections (NB-ARTI) and identify targets reducing inappropriate NB-ARTI Japan. Methods We conducted retrospective, observational study using longitudinal claims data between April 2012 June...
Abstract In early 2020, Japan repatriated 566 nationals from China. Universal laboratory testing and 14-day monitoring of returnees detected 12 cases severe acute respiratory syndrome coronavirus 2 infection; initial screening results were negative for 5. Common outcomes remaining asymptomatic (n = 4) pneumonia 6). Overall, performed poorly.
Among patients with coronavirus disease 2019 (COVID-19), the factors that affect anti-severe acute respiratory syndrome 2 (SARS-CoV-2) antibody production remain unclear. This study aimed to identify such among convalescing from COVID-19.This comprised who had been diagnosed COVID-19 between January 1 and June 30, 2020 gave consent for anti-SARS-CoV-2 spike protein measurement using enzyme-linked immunosorbent assay during their and/or convalescent phases. Factors related elevated titers...
Due to the significant spread of a new type coronavirus (SARS-CoV-2) infection (COVID-19) in China, Chinese government blockaded several cities Hubei Province. Japanese citizens lost means transportation return back Japan. The National Center for Global Health and Medicine (NCGM) helped operation charter flights evacuation residents from Province, this article outlines our experiences. A total five were dispatched, majority returnees (793/829 [95.7%]) handled at NCGM. large number personnel...
In order to tackle the COVID-19 pandemic, a convalescent plasma (CCP) procurement program was initiated in Japan April 2020. The collaboration between government-managed national hospital, an infectious disease research institute, and blood banking organization. Each party assumed different responsibilities: recruitment, SARS-CoV-2 antibody profiling, plasmapheresis; conduction of screening tests; testing, respectively.We adopted two-point approach before collected CCP labeled as product for...
Abstract Predicting the need for hospitalisation of patients with coronavirus disease 2019 (COVID-19) is important preventing healthcare disruptions. This observational study aimed to use COVID-19 Registry Japan (COVIREGI-JP) develop a simple scoring system predict respiratory failure due using only underlying diseases and symptoms. A total 6873 admitted Japanese medical institutions between 1 June 2020 2 December were included divided into derivation validation cohorts according date...