- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Pain Mechanisms and Treatments
- Health and Wellbeing Research
- Child Development and Digital Technology
- Frailty in Older Adults
- Effects and risks of endocrine disrupting chemicals
- Diet, Metabolism, and Disease
- Alcoholism and Thiamine Deficiency
- Allergic Rhinitis and Sensitization
- Diet and metabolism studies
- Dental Health and Care Utilization
- Vitamin C and Antioxidants Research
- Musculoskeletal pain and rehabilitation
- Mobile Health and mHealth Applications
- Tryptophan and brain disorders
- Contact Dermatitis and Allergies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pharmacology and Obesity Treatment
- Folate and B Vitamins Research
- Advanced Glycation End Products research
- Animal testing and alternatives
- Impact of Technology on Adolescents
- Health, psychology, and well-being
Tokyo Women's Medical University
2024-2025
University of Fukui
2012-2024
National Sanyo Hospital
2024
University of Fukui Hospital
2022
Kanazawa University
2012-2013
Background/Objectives: Macronutrients (protein, fat, and carbohydrate) provide sources of energy play crucial roles in various physiological functions. However, sex differences the relationships between protein, carbohydrate intakes all-cause mortality remain unclear. The present study investigated using longitudinal epidemiological data. Methods: A total 3743 healthy residents (1666 men 2077 women) aged 40 years or older were followed up (men: 6.64 ± 1.51 years, women: 6.76 1.28 from 2013)...
Sedentary behaviors have recently become an important public health issue. We aimed to investigate the relationship between screen time and nutrient intake in children adolescents. The present study was conducted 2013. Data were collected from adolescents aged 6 15 years old Shika town. Questionnaires distributed 1459 subjects, 1414 of whom participated (96.9%). assessed based on participants' (television (TV) viewing, personal computer (PC) use, mobile phone (MP) use). main outcomes...
The aim of this study was to examine potential differences the associations between mental health and lifestyle factors across a wide range age.In August/September 2011, data were collected from 4693 males (age 51.6 ± 19.5) 5678 females 52.4 19.4) living in Kanazawa, Japan. A cross-sectional community-based survey conducted with self-administered questionnaire including General Health Questionnaire (GHQ) 12-item version, sociodemographic, factors. Associations GHQ scores other variables...
Objects Identification of biomarkers for Alzheimer's disease (AD) is important its early diagnosis and prevention a key in advancing our understanding pathophysiology. The aim this study was to determine whether systemic inflammatory interleukin‐1ß (IL‐1ß) interleukin‐6 (IL‐6) as well hypertension (HT), diabetes mellitus (DM), body mass index (BMI) are predictors AD. Methods We performed 10‐year follow‐up on 133 elderly who were institutionalized nursing home. associations IL‐1ß IL‐6 at both...
The association between heavy metals exposure and respiratory diseases or allergic sensitization showing high serum immunoglobulin E (IgE) has been suggested. However, previous findings have inconsistent the mechanisms responsible remain unclear. We evaluated metal its with coughing, itchy eyes in chronic cough patients different IgE levels. Ninety outpatients Kanazawa University Hospital were recruited January-June 2011. Subjects whose total measured by radioimmunosorbent test asked to...
The relationship between oral frailty (OF) and bone mineral density is unclear. This cross-sectional study analyzed the intake in middle-aged older people with pre-oral OF. participants, which included 240 aged 40 years older, completed three questions on Kihon Checklist (KCL), a self-reported comprehensive health checklist, brief-type self-administered diet history questionnaire (BDHQ), osteo-sono assessment index (OSI). A two-way analysis of covariance function OSI indicated that...
The prevalence of allergic diseases, such as bronchial asthma, atopic dermatitis, nasal allergies (pollinosis), and food allergies, has been increasing in many countries. hygiene hypothesis was recently considered from the perspective exposure to antimicrobial agents preservatives, parabens (CAS number, 94-13-3). It currently remains unclear whether parabens, which are included daily consumer products cosmetics, shampoos, personal care preservative agents, induce or aggravate allergies....
Atopic dermatitis (AD) and Japanese cedar pollinosis (JCP) are common chronically allergic diseases associated with the activation of T-helper 2 cells. Recent studies have shown that polymorphisms in genes for IL-4 receptor α chain (IL4RA) may contribute to susceptibility AD JCP, although differences involvements loci IL4RA gene between JCP unclear. In this study, we investigated role IL-4RA conferring development and/or using a family analysis an association population. Five gene, C-3223 T,...
Although epidemiological studies revealed a relationship between psychosocial states, such as depressive symptoms, and nutritional intake, limited information is currently available on vitamin intake. The Short Form-36 Health Survey (SF-36) not to specific disease, it constructed based universal concept of health used evaluate the Quality life (QOL). A three-component scoring method was developed for “Physical component score (PCS)”, “Mental (MCS)”, “Role/social (RCS)”. Collectively, these...
Alzheimer's disease (AD) impairs cognitive functions, subsequently decreasing activity of daily living (ADL), and is frequently accompanied by lower limb fracture including hip in the elderly. However, there have been few studies on what kinds physical functions are affected or degrees dysfunction produced this combination. This study aims to clarify relationship between decreased ADL combination AD fracture.We examined present illness 4340 elderly aged 82.8 ± 9.36 years [average standard...
Although depression and body weight have individually been associated with chronic pain (CP), it currently remains unclear whether the combination of depressive symptoms (DS) being underweight/overweight is related to CP. Therefore, we herein investigated relationships among depression, mass index (BMI), CP in community-dwelling middle-aged elderly individuals. Participants comprised 2216 inhabitants Shika town Ishikawa prefecture, Japan, including 1003 males (mean age 68.72 years, standard...
The aim of this study was to evaluate the prevalence chronic pain (CP) and relationship between CP, especially headache adjusted for CP at other sites, health-related quality life (HRQoL) in middle-aged Japanese residents. We examined (defined as persisting 3 months or more) HRQoL (SF-36) 1117 residents Japan. assessed eight dimensions health status component SF-36 summary score HRQoL. 15.3% among men 15.1% women. Multiple linear regression analysis demonstrated that lumbar (p β = -0.132),...
Chronic kidney disease (CKD) patients have been advised to take vitamins; however, the effects controversial. The individual differences in developing CKD might involve genetic variants of inflammation, including variant rs883484 located upstream prostaglandin-endoperoxide synthase 1 (PTGS1) gene. We aimed identify whether 12 dietary vitamin intake interacts with genotypes on CKD. population-based, cross-sectional study had 684 Japanese participants (≥40 years old). used a validated, brief,...
Background: Situs inversus is a rare complication of cystic kidney diseases. Only three genes, INVS (NPHP2), NPHP3 and PKD2 have been proved to be responsible for some cases, while the genes in many others are still unknown. Case Reports: Here we report two male patients with situs combined disease without any family history polycystic disease. Their renal function was normal childhood but culminated end stage middle age. No pathogenic mutations were found mutation analysis INVS, IFT88,...
The association between oral frailty (OFr) and body action has been investigated, but its with systemic function remains unclear. Therefore, this cross-sectional study examined the OFr decreased bone mineral density (BMD) renal in residents of Shika town, Ishikawa Prefecture, Japan aged ≥40 years. This included 400 inhabitants. total score was assessed using three domains Kihon Checklist (a self-reported comprehensive health checklist), number teeth, brushing frequency per day. Measurements...
Although nutrient intake and alcohol consumption are both closely associated with the incidence of diabetes, their interrelationships remain unclear. Therefore, we herein have investigated among intake, consumption, diabetes using longitudinal data. This study included 969 residents ≥40 years living in Japan. In 2011 2012, a baseline was conducted questionnaires on basic demographics, lifestyle habits. 2018 2019, follow-up performed medical records diabetes. Two-way analysis covariance...
It currently remains unclear whether parabens, which are preservatives added to cosmetics, shampoos, and personal care products that exhibit biocidal activities, exert allergic effects in adults. The aim of the present study was examine relationship between use parabens prevalence diseases Japanese This population-based cross-sectional comprised 2005 participants aged 40 years or older living Shika Town Japan who answered a self-administered questionnaire on daily household goods....
Although alcohol intake is associated with chronic pain (CP) and analgesia, epidemiological studies have not yet examined the factors affecting relationship between CP in detail. Therefore, present cross-sectional study investigated community-dwelling middle-aged elderly individuals with/without depressive symptoms. Participants comprised 2223 inhabitants of Shika town Ishikawa prefecture, located on Noto Peninsula facing Sea Japan, included 1007 males 1216 females. CP, symptoms, were...
Although the relationship between hypertension and depression is influenced by several physiological factors, including body weight other lifestyle such as eating behavior, specific involvement of in remains unclear. Therefore, this epidemiological study examined role depressive symptoms among middle-aged elderly living community Shika town. In total, 1141 males 1142 females with mean ages 69.09 70.61 years, respectively, participated study. Physiological blood pressure, mass index (BMI),...
Objective To investigate the relationship between oral frailty (OF), nutrient intake and calf circumference (CC) in middle-aged older adults. Design Cross-sectional study. Setting Residents of four model districts Shika town, Ishikawa Prefecture, Japan, using data from November 2017 to February 2018. Participants One hundred ninety-four residents aged ≥50 years town. The OF total score ≥3 was defined as OF. were divided into non-OF groups low-CC/kg high-CC/kg groups. Outcome measures primary...
Background: Concerns regarding the impact of screen-based sedentary behavior on health have been increasing. Therefore, present study investigated longitudinal relationship between multiple screen time and nutrient intake in children adolescents.
Abstract Although the relationship between dyslipidaemia (DL) and coronary artery disease (CAD) or trace minerals intake CAD is well known separately, exact nature of this remains unknown. We hypothesize that mineral may differ depending on whether not individual has DL. The present study analysed relationships among intake, DL, in middle-aged older adults living Shika town, Ishikawa prefecture, Japan. This included 895 residents following exclusion those with genetic risk carriers for...
Abstract Although chronic pain (CP) is classified as inflammatory or non-inflammatory, the involvement of fatty acid intake in this process has not yet been examined detail. Therefore, present study investigated whether relationship between CP and differs high low C-reactive protein (CRP) levels middle-aged elderly individuals Shika study. One-thousand seven males 1216 females with mean ages 68⋅78 69⋅65 years, respectively, participated CRP was quantified by blood sampling from participants...