A5031701959- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Dental Health and Care Utilization
- Breastfeeding Practices and Influences
- Oral microbiology and periodontitis research
- Infant Development and Preterm Care
- Obesity and Health Practices
- Growth Hormone and Insulin-like Growth Factors
- Food Security and Health in Diverse Populations
- Gestational Diabetes Research and Management
- Infant Nutrition and Health
- Gut microbiota and health
- Child Nutrition and Water Access
- Dental Erosion and Treatment
- Metabolism and Genetic Disorders
- Attention Deficit Hyperactivity Disorder
- Healthcare Systems and Reforms
- Cleft Lip and Palate Research
- Adipokines, Inflammation, and Metabolic Diseases
- Eating Disorders and Behaviors
- Cardiovascular Disease and Adiposity
- Salivary Gland Disorders and Functions
- Child Nutrition and Feeding Issues
- Diet and metabolism studies
- Body Composition Measurement Techniques
University of Gothenburg
2014-2024
Hallands sjukhus Halmstad
2015-2024
Spine Center Göteborg
2014
Measurement of IGF-I is a cornerstone in diagnosis and monitoring GH-related diseases, but considerable discrepancies exist between analytical methods. A recent consensus conference defined criteria for validation assays establishment normative data.Our objectives were development novel automated immunoassay (iSYS; Immunodiagnostic Systems) according to international guidelines method-specific age- sex-adjusted reference intervals analysis their robustness.We conducted multicenter study with...
The gut is inhabited by a densely populated ecosystem, the microbiota, that established at birth. However, succession which different bacteria are incorporated into microbiota still relatively unknown. Here, we analyze from 471 Swedish children followed birth to 5 years of age, collecting samples after 4 and 12 months 3 age as well their mothers using 16S rRNA gene profiling. We also compare an adult population. Genera follow colonization patterns during establishment where...
Breastfeeding is associated with many benefits for both mother and child. Initiation rates are high in Sweden. Recently a slight decline seen.The aim of this study was to assess factors discontinuation breastfeeding during the first 4 weeks.A population-based longitudinal birth cohort recruiting from 2007 2008 south-western At visit child health centre, parents were asked complete questionnaire. Also, infants' height, weight, head waist circumference collected. Response rate...
Measurement of IGF-binding protein-3 (IGFBP-3) can aid the diagnosis GH-related diseases. Furthermore, epidemiological studies suggest that IGFBP-3 and molar IGF-I to ratio are associated with clinical end points like cancer or cardiovascular disease. However, their use is limited by lack validated reference intervals. The objective study was establishment age- sex-specific intervals for newly developed automated immunoassays. This a multicenter samples from 11 cohorts United States, Canada,...
To study the relationship between tooth-brushing habits during preschool ages and caries prevalence at age of 5 years to investigate a possible association with mode delivery.The population consisted 336 children that were orally examined 2, 3 years. All stages scored on tooth surface level. Data brushing behaviour collected through semi-structured interviews.At years, attrition rate was 13.1%. The total (cavitated non-cavitated lesions) 18.9%. vast majority parents assisted their child 98%...
To establish new reference values for measurements of waist circumference and waist-to-height ratio in preschool children.A population-based, cross-sectional study 4502 children aged 0-5 years derived from child health care a Swedish county. Measurements weight, height were recorded using standardized procedure.New are presented. Reference charts constructed Waist increased with age (r = 0.80, p < 0.001). After adjustment to the individual height, expressed as ratio, there was an inverse...
Abstract Aim To investigate the prevalence of attention‐deficit/hyperactivity disorder (ADHD) and autism spectrum (ASD) in a population‐based birth cohort correlate findings with prenatal perinatal factors. We hypothesized that children born preterm, having experienced preeclampsia or maternal overweight, would have an increased risk ADHD ASD. Method A Swedish 2666 (1350 males, 1316 females) has been followed from parental data. The National Board Health Welfare's registries were used to...
Introduction: Conflicting results exist regarding mode of delivery and caries. We investigated the influence selected family- nursing factors during first 2 years life on prevalence dental caries at 5 years.Materials methods: 551 infants were invited to a prospective medical study with focus growth overweight prevention. The parents 346 (179 boys 167 girls) accepted this invitation age 2-years, 336 them agreed check-ups salivary samplings. At ages three five years, 302 (90%) 292 children...
Aim Infant feeding affects growth, obesity and life-long health. This study examined the impact of dietary patterns on body mass index (BMI) at 12 18 months. Methods We followed a cohort 2666 children recruited in 2007–2008. Feeding practices were obtained from parental questionnaires anthropometric data collected by child health nurses. Results At 6 months, 58.3% infant breastfed, but only 1.6% exclusively. Many had begun eating solids (91.8%), porridge (87.7%) or milk cereal drink (46.6%)....
Abstract Background Rapid weight gain (RWG) during infancy increases the risk of excess later in life. Nutrition- and feeding practices associated with RWG need to be further examined. The present study aimed examine nutrition- practice-related factors for first year Methods A population-based longitudinal birth cohort 1780 infants, classified as having or non-RWG 0–3-4, 0–6 6–12 months. was defined a change > 0.67 standard deviation scores. Associations between were examined logistic...
To study the relationship between early childhood caries and perinatal metabolic risk factors in a cohort of preschool children.The population consisted 208 children followed from birth to 6.5 years. We extracted medical records questionnaires assessed occurrence at age 5 Indicators syndrome (waist circumference, blood pressure, fasting insulin, glucose dyslipidaemia) were recorded years age.Infants born moderately late preterm infants small for gestational more likely have (relative 4.2...
Previous cross-sectional studies have suggested that the mode of delivery can influence composition oral microflora. The aim this prospective study was to compare salivary colonization in vaginally delivered children with by Caesarian section (C-section) during their first 6 months life.The group consisted 149 consecutively enrolled infants, either (n = 96) or C-section 53) volunteered after consent parents. Saliva samples were collected within 2 days birth and then 1, 3, months. A saliva...
Abstract Aim Metabolic syndrome represents a cluster of risk factors for cardiovascular disease, and we investigated whether otherwise healthy 6‐year‐olds showed metabolic alterations. Methods This study followed up representative Swedish population‐based cohort full‐term infants recruited on the maternity ward at Hallands Hospital Halmstad, Sweden, from 2008 to 2011. They were examined mean 6.6 years age (range 6.5–6.9) using various measures signs syndrome. Results One key measure that 55...
A number of child/parental factors have been shown to be significant predictors childhood overweight, although a better understanding possible contextual influences neighbourhood-level characteristics might provide new insights leading tailored, targeted interventions. The aim this study was explore the impact neighbourhood purchasing power and its relationship with other known risk related overweight in prospective birth cohort. prospective, population-based, birth-cohort conducted...
To investigate the development of waist circumference (WC) in preschool children born preterm compared with a population-based reference.Children are reported to be insulin resistant, despite being lean during early childhood. We hypothesize that mechanism is through increased visceral adiposity.Data from 4446 (2169 girls/2277 boys) 2001-2006 study were longitudinal measurements body mass index (BMI) and WC cohort 152 (64 girls/88 moderately 2002-2004 (gestational age, 32-37 weeks).In...
Abstract Objective The longitudinal variations in serum levels of the hormone osteocalcin is largely unknown during infancy and early childhood. Our aim was to establish reference limits for total specific time points from birth until 5 years age present those context sex, breastfeeding practices gestational (GA). Design Blood samples 551 Swedish children were analysed at birth, 4, 12, 36 60 months age. Total measured using IDS‐iSYS N‐MID Osteocalcin assay technique. Information about...
The aim of this study was to the relationship between insulin-like growth factor-1 (IGF-1), serum phospholipid fatty acids, and in healthy full-term newborns during infancy.Prospective observational a population-based Swedish cohort comprising 126 healthy, term infants investigating cord blood at 2 days 4 months age for IGF-1 acid profile breast milk acids months, compared with anthropometric measurements (standard deviation scores).At all time-points arachidonic (AA) negatively associated...
This study examined whether the parents of children who were overweight at two and five years age perceived their as being too heavy related findings to sociodemographic factors.The data collection included parental questionnaires anthropometric from a longitudinal birth cohort 2666 born in south-west region Sweden 2007-2008.We found that 14.9 11.8% considered or obese five, but 96.4 87.1% weight be just about right these ages. The difference was statistically significant (p < 0.001)....
Abstract Aim We previously reported that consuming milk cereal drinks at six months of age was associated with a high body mass index ( BMI ) 12 and 18 months. This study examined the association between daily consumption five. Methods followed up 1870/2666 (70%) children recruited birth in 2007–2008 for Swedish longitudinal population‐based Halland Health Growth Study mean 5.09 ± 0.28 years. Feeding practices were obtained from parental questionnaires, anthropometric data collected by child...
Parental socioeconomic status (SES) is an important determinant in child health, influencing beneficial factors such as breastfeeding. A better understanding of the influence neighbourhood-level SES measures, relating to spatial determinants, might lead targeted actions promote breastfeeding during infancy.A cross-sectional study analysis association between at four months age and neighbourhood purchasing power, taking account individual-level variables including maternal age, smoking...
Brown adipose tissue is of metabolic interest. The however poorly explored in children.Sixty-three 7-year old subjects from the Swedish birth-cohort Halland Health and Growth Study were recruited. Care was taken to include both normal weight overweight children, but otherwise healthy. Only children born full term included. Water-fat separated whole-body MRI scans, anthropometric measurements, measurements fasting glucose levels energy homeostasis related hormones, including...