- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Blood Coagulation and Thrombosis Mechanisms
- Intracerebral and Subarachnoid Hemorrhage Research
- Healthcare Systems and Practices
- Cerebrovascular and Carotid Artery Diseases
- Cerebral Venous Sinus Thrombosis
- Streptococcal Infections and Treatments
- Clinical practice guidelines implementation
- Hip and Femur Fractures
- Bacterial Infections and Vaccines
- Parasites and Host Interactions
- Liver Disease and Transplantation
- Tumors and Oncological Cases
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations and Hemangiomas
- Viral Infections and Immunology Research
- Health and Well-being Studies
- Infective Endocarditis Diagnosis and Management
- Infectious Diseases and Tuberculosis
- Renal and Vascular Pathologies
- Liver Disease Diagnosis and Treatment
- Child Nutrition and Water Access
Catholic University of Health and Allied Sciences
2020-2025
Bugando Medical Centre
2022-2025
Muhimbili National Hospital
2024
European Stroke Organisation
2024
Muhimbili University of Health and Allied Sciences
2021
Over the past few years, incidence and prevalence of stroke has been rising in most African countries reported as one leading causes morbidity mortality. To study this problem, we need to realize quality availability care services a priori improve them.In study, investigated different stroke-related 17 from regions. An online survey was conducted fulfilled by specialists included primary prevention, acute management, diagnostic tools, medications, postdischarge services, registries. The...
Background Current stroke guidelines recommend advanced imaging (computed tomography [CT] perfusion or magnetic resonance imaging) prior to endovascular therapy (EVT) in patients with late presentation of large vessel occlusion. Adherence may be constrained by resources timely access imaging. We sought understand the factors which influence window selection for EVT candidates Methods conducted an international survey from January May 2022. The questions aimed identify and treatment decisions...
Abstract Background As one of the most common non-communicable diseases in Africa, Stroke ought to be dealt with properly intensifying efforts control its burden and face obstacles management. Methods Results In this follow-up study we reanalyzed stroke services related 17 African countries that were previously studied 2021/22 aspects manpower, acute services, rehabilitation programs, number units/centers, telestroke awareness campaigns, national international registries through a survey was...
The development of vascular neurology as the primary specialty for stroke evaluation and treatment is a relatively recent advancement. Vascular well-established in United States, ensuring most patients receive specialized care, but many globally are managed by physicians without training cerebrovascular neurological medicine that partly manifested availability institutions incorporate dedicated training. Our goal to evaluate providers worldwide identify who leading care different regions,...
Background: Telestroke has proven efficacy in improving clinical outcomes by providing rapid access to specialized stroke care, particularly remote areas. However, the global implementation of telestroke networks remains uneven, with limited data on their structure and coverage outside high-income countries (HICs). Objective: This study aimed provide a comprehensive overview landscape networks, highlighting disparities underscoring need for universal guidelines. We map landscape,...
Background: Stroke is a leading cause of long-term disability worldwide. Timely and adequate rehabilitation crucial for post-stroke recovery, but access limited due to an overburdened healthcare system, medical personnel shortages, insurance barriers. Rehabilitation especially stroke survivors in rural low-income regions. Innovative solutions like telerehabilitation are needed expand access. This study examines current practices, costs, global models, as well barriers utilization. Methods:...
Background The most frequent electrolyte derangement in adults with stroke is hyponatremia, which associated increased morbidity, mortality, and prolonged hospital stay. study aimed to investigate the hyponatremia incidence 30-day outcomes among admitted at a large tertiary teaching Northwestern Tanzania. Methods This cohort recruited presenting first-ever (as defined by World Health Organization) between November 2023 May 2024. Data were collected on demographics, degree of neurological...
Stroke is the second leading cause of death worldwide, with highest mortality rates in low- to middle-income countries, particularly sub-Saharan Africa. We aimed investigate predictors 30-day among patients stroke admitted at a tertiary teaching hospital Northwestern Tanzania.This cohort study recruited World Health Organization's clinical definition stroke. Data were collected on baseline characteristics, degree neurological impairment admission (measured using National Institutes Scale),...
Abstract Background Stroke burden in young adults is growing associated with unique risk factors and devastating outcomes. We aimed to investigate the magnitude, outcomes of first ever stroke ≤45 years compared older > 45 years. Methods All patients a World Health Organization clinical definition at tertiary hospital Tanzania were enrolled. The National Institute Scale Modified Rankin used assess admission severity respectively. Kaplan-Meier analysis was describe survival Cox-proportional...
Background and Aims: Hepatic encephalopathy, a neuropsychiatric syndrome caused by portosystemic venous shunting, clinical presentation ranges from minimal to overt H.E. It is common complication of advanced liver disease with significant morbidity mortality The aim this study was assess the prevalence, precipitating factors, outcomes hepatic encephalopathy in patients preexisting disease. Methods: A hospital based, retrospective chart review conducted at Bugando Medical Centre tertiary...
Despite the proven efficacy of telestroke in improving clinical outcomes by providing access to specialized expertise and allowing rapid expert hyperacute stroke management decision-making, detailed operational evidence is scarce, especially for less developed or lower - income regions.
The purpose of this article is to discuss the global impact stroke, disparities and barriers implement stroke care, efforts improve access acute treatments in low middle-income countries (LMICs).
Background: Stroke is a second leading cause of death globally, with an estimated one in four adults suffering stroke their lifetime. We aimed to describe the clinical characteristics, quality care, and outcomes urban Northwestern Tanzania. Methods: analyzed de-identified data from prospective registry Bugando Medical Centre Mwanza, largest city Tanzania, between March 2020 October 2022. This included all ⩾18 years admitted our hospital who met World Health Organization definition stroke....
Background Stroke contributes to a significant proportion of deaths and disability worldwide, with high fatality rate within 30 days following first ever stroke. We describe the outcomes one year among patients who succumbed stroke survived days. Methods Participants were after from succumbing admitted at Muhimbili University Health Allied Sciences Academic Medical Center. survivors or their next kin contacted determine outcomes. assessed participants’ vital status level using modified...
Large vessel ischemic strokes account for more than one-third of all associated with substantial morbidity and mortality without early intervention. The incidence large occlusion (LVO) is not known in sub-Saharan Africa (SSA). Definitive imaging routinely available resource-limited settings. We aimed to investigate the burden outcomes presumed LVO among patients stroke admitted a tertiary academic hospital Tanzania. This cohort study recruited consenting first-ever participants at...
Abstract Background: Stroke burden in young adults is growing associated with unique risk factors and devastating outcomes. We aimed to investigate the magnitude, outcomes of first ever stroke ≤45 years compared older >45 years. Methods: All patients a World Health Organization clinical definition at tertiary hospital Tanzania were enrolled. The National Institute Scale Modified Rankin used assess admission severity respectively. Kaplan-Meier analysis was describe survival...
Blindness and vision impairment are unpredictable complications of tuberculous meningitis (TBM) that often unrecognized in the acute stages illness due to inability assess patients with depressed levels consciousness or confusion. We present a patient definite TBM confirmed by positive Xpert MTB/RIF assay cerebrospinal fluid (CSF) who developed binocular blindness two weeks after diagnosis initiation standard anti-tuberculosis treatment (ATT). Ophthalmological exam demonstrated complete...
Stroke mimics account for up to one-third of acute stroke admissions and are a heterogeneous entity which pose diagnostic challenges. Diagnosing such patients is however crucial avoid delays in treatment potentially harmful medication prescription. We aimed at describing the magnitude, clinical characteristics short-term outcomes clinically diagnosed with stroke.This prospective study enrolled admitted World Health Organization criteria tertiary hospital Tanzania. Baseline data was collected...
Despite stroke being a leading cause of death and disability in sub-Saharan Africa, awareness remains major hurdle to early response care the region. To improve awareness, we endeavoured borrow leaf from initiatives high-income countries, beginning with translation dissemination acronym, FAST (Face, Arms, Speech, Time) Swahili.
Introduction Stroke is a leading cause of morbidity and mortality globally with high social economic burden that disproportionately effects low‐ middle‐income countries (LMICs). Mechanical thrombectomy (MT) an effective treatment for stroke but not available in the majority LMICs. Tanzania (TZ) lacks MT has limited access to thrombolytics very few patients receiving any intervention acute ischemic (AIS). Key stakeholders TZ are motivated build program provide AIS, including MT. Here we...
Introduction Mechanical thrombectomy (MT) has revolutionized care for patients with ischemic strokes from large vessel occlusion (LVO) leading to adoption as the standard of care. However, Thrombectomy Global Access For Stroke (MT‐GLASS) study, demonstrated that global access mechanical is <3% demand. One possible reason these shortcomings are significant resources required develop a sustainable MT service. Our aim understand what infrastructure, equipment and staff essential perform safe...