- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Circadian rhythm and melatonin
- Estrogen and related hormone effects
- Antioxidant Activity and Oxidative Stress
- Pharmaceutical studies and practices
- Neurological Disorders and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac Fibrosis and Remodeling
- Cancer Treatment and Pharmacology
- Neurological Disease Mechanisms and Treatments
- GDF15 and Related Biomarkers
- Phosphodiesterase function and regulation
- Optical Imaging and Spectroscopy Techniques
- Pediatric Pain Management Techniques
- Ethics and Legal Issues in Pediatric Healthcare
- Cervical Cancer and HPV Research
- Connective Tissue Growth Factor Research
- Intracranial Aneurysms: Treatment and Complications
Johns Hopkins University
2023
Chonnam National University
2012-2018
Institute of Forensic Science
2018
Myongji Hospital
2014
Armed Forces Capital Hospital
2004
Abstract Gallic acid is a trihydroxybenzoic found in tea leaves and some plants. Here, we report the effect of gallic on cardiac dysfunction fibrosis mouse model pressure overload-induced heart failure primary rat fibroblasts, compare effects with those drugs used clinics. reduces hypertrophy, dysfunction, induced by transverse aortic constriction (TAC) stimuli vivo transforming growth factor β1 (TGF-β1) vitro . It decreases left ventricular end-diastolic end-systolic diameter, recovers...
(Cell Reports 32, 107861-1–14.e1–e7; July 7, 2020) In the originally published version of this article, author name Jung Moo Lee was spelled incorrectly. This has now been corrected online. The authors regret error. Excessive Astrocytic GABA Causes Cortical Hypometabolism and Impedes Functional Recovery after Subcortical StrokeNam et al.Cell ReportsJuly 07, 2020In BriefNam al. demonstrate that excessive from reactive astrocytes accounts for cortical glucose hypometabolism followed by...
Background: Evans blue dye (EBD) is the most common indicator to analyze extent of blood-brain barrier (BBB) breakdown in several neurological disease models. However, high-dose EBD (51.9 mg/kg) usually required for visualization color by human eye that brings potential safety issues. Methods: To solve this problem, low-dose was applied near-infrared (NIR) fluorescence-assisted quantitation BBB photothrombotic stoke model. Animals were allocated seven dose groups ranging from 1.35 nmol (5.19...
Vertebral artery hypoplasia (VAH) can be easily overlooked if the contralateral side vertebral is intact, because of compensation by or cerebral collateral network. The clinical relevance and hemodynamic impact VAH still controversial. However, has recently been considered a risk factor for posterior circulation ischemia. Ischemic stroke seldom caused free floating thrombi (FFT) in artery. Pathophysiology FFT not yet clarified. state reduced blood flow such as origin stenosis may cause FFT....