A5034884110- Analytical Chemistry and Sensors
- Gas Sensing Nanomaterials and Sensors
- Quantum Dots Synthesis And Properties
- Advanced Chemical Sensor Technologies
- Advanced Fiber Optic Sensors
- Organic Light-Emitting Diodes Research
- Nanowire Synthesis and Applications
- Semiconductor materials and devices
- Conducting polymers and applications
- Thin-Film Transistor Technologies
- Organic Electronics and Photovoltaics
- Perovskite Materials and Applications
- Advanced biosensing and bioanalysis techniques
- Photonic and Optical Devices
- Chalcogenide Semiconductor Thin Films
- ZnO doping and properties
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Advanced MRI Techniques and Applications
- Anodic Oxide Films and Nanostructures
- Ga2O3 and related materials
- Advanced Sensor and Energy Harvesting Materials
- GaN-based semiconductor devices and materials
- Diamond and Carbon-based Materials Research
- Advanced Neuroimaging Techniques and Applications
Korea University
1998-2022
Kyungil University
2010-2020
Gwangju Institute of Science and Technology
2015-2020
University of Suwon
2018-2019
Kyungpook National University
2005-2016
Charles R. Drew University of Medicine and Science
2011
Gachon University
2011
Louisiana State University
1998
Abstract Objective: To investigate anatomical changes in the substantia nigra (SN) of Parkinson disease (PD) patients with age‐matched controls by using ultra‐high field magnetic resonance imaging (MRI). Methods: We performed 7T MRI 10 PD and control subjects. Magnetic images SN were obtained from a 3‐dimensional (3D) T 2 *‐weighted gradient echo sequence. Region interest‐based 3D shape analysis was to quantitatively compare groups. Results: The boundary between crus cerebri not smooth...
Abstract Parkinson's disease (PD) is a neurodegenerative disorder resulting from progressive loss of dopaminergic neurons in the substantia nigra (SN) pars compacta. Therefore, imaging SN has been regarded to hold greatest potential for use diagnosis PD. At 7.0T magnetic resonance (MRI), it now possible delineate clearly shapes and boundaries SN. We scanned eight early two advanced PD patients, along with nine age‐matched control subjects, using MRI an attempt directly visualize quantify...
Glucose hypometabolism in cortical structures after functional disconnection is frequently reported patients with white matter diseases such as subcortical stroke. However, the molecular and cellular mechanisms have been poorly elucidated. Here we show, an animal model of internal capsular infarct, that GABA-synthesizing reactive astrocytes distant areas cause glucose via tonic inhibition neighboring neurons. We find reversal aberrant astrocytic GABA synthesis, by pharmacological...
We propose a design for highly sensitive biosensor based on nanostructured anodized aluminum oxide (AAO) substrates. A gold-deposited AAO substrate exhibits both optical interference and localized surface plasmon resonance (LSPR). In our sensor, application of these disparate properties overcomes problems limited sensitivity, selectivity, dynamic range seen in similar biosensors. fabricated uniform periodic nanopore lattice templates by two-step anodizing assessed their suitability...
We demonstrate the first-ever surface modification of green CdSe/ZnS quantum dots (QDs) using bromide anions (Br-) in cetyl trimethylammonium (CTAB). The Br- ions reduced interparticle spacing between QDs and induced an effective charge balance QD light-emitting devices (QLEDs). fabricated QLEDs exhibited efficient injection because emission quenching effect their enhanced thin film morphology. As a result, they maximum luminance 71,000 cd/m2 external current efficiency 6.4 cd/A, both...
The subthalamic nucleus (STN) controls psychomotor activity and is an efficient therapeutic deep brain stimulation target in individuals with Parkinson's disease. Despite evidence indicating position-dependent effects distinct functions within the STN, input circuit cellular profile STN remain largely unclear. Using neuroanatomical techniques, we construct a comprehensive connectivity map of indirect hyperdirect pathways mouse STN. Our circuit- cellular-level connectivities reveal...
In this paper, we demonstrate a facile, mild wetting (short residence time) poor solvent [isopropyl alcohol (IPA)] treatment, carried out on the top surface of spin-cast poly (3-hexylthiopene) (P3HT) and [6,6]-phenyl-C71-butyric acid methyl ester (PCBM) blend film, in order to fabricate high-performance polymer solar cells (PSCs). This method utilizes hydrophilic polar/hydrogen bonding interactions IPA with components (P3HT PCBM). The photovoltaic (PV) performance fabricated PSCs was...
Nickel silicide (NiSi) was formed by annealing a uniform low-resistivity nickel (Ni) film deposited atomic layer deposition (ALD). A Ni as-deposited at 220 °C exhibited the lowest sheet resistance of 18 Ω/sq. comparable to that obtained physical vapor deposition, even though it contained significant amount carbon from metalorganic precursor. It is believed uniformly distributed in partly forming weak Ni3C phase which eliminates other crystalline defects and hence lowers film. However, not...
We propose a solution-processable ultraviolet (UV) photodetector with pn-heterojunction hybrid photoactive layer (HPL) that is composed of poly-n-vinylcarbazole (PVK) as p-type polymer and ZnO nanoparticles (NPs) an n-type metal oxide. To observe the effective photo-inducing ability UV photodetector, we analyzed optical electrical properties HPL which controlled by doping concentration NPs in PVK matrix. Additionally, confirmed dominantly depend on from UV-vis absorption photoluminescence...
(Cell Reports 32, 107861-1–14.e1–e7; July 7, 2020) In the originally published version of this article, author name Jung Moo Lee was spelled incorrectly. This has now been corrected online. The authors regret error. Excessive Astrocytic GABA Causes Cortical Hypometabolism and Impedes Functional Recovery after Subcortical StrokeNam et al.Cell ReportsJuly 07, 2020In BriefNam al. demonstrate that excessive from reactive astrocytes accounts for cortical glucose hypometabolism followed by...
Abstract InGaAs-based photodetectors have been generally used for detection in the short-wave infrared (SWIR) region. However, epitaxial process to grow these materials is expensive; therefore, are limited space exploration and military applications. Many researchers expended considerable efforts address problem of SWIR photodetector development using lead sulfide (PbS) quantum dots (QDs). Along with their cost-efficient solution processability flexible substrate compatibility, PbS QDs...
We propose a highly efficient hybrid light-emitting device (LED) with single active layer where CdSe/ZnS quantum dots (QDs) are dispersed as guest material in conjugated polymer (co-polymer) matrix used for host material. In our structure, the QDs act on chromophores by trapping migrating excitons co-polymer via Förster energy transfer, and improve charge balance within injected electron carriers. Experimental results show that electroluminescent properties depend doping density of matrix,...
We propose a nanobiosensor to evaluate lung cancer‐specific biomarker. The is based on an anodic aluminum oxide (AAO) chip and functions the principles of localized surface plasmon resonance (LSPR) interferometry. pore‐depth fabricated nanoporous AAO was 1 µ m obtained using two‐step electrochemical anodization process. sensor sensitive refractive index (RI) changes surrounding medium also provides simple label‐free detection when specific antibodies are immobilized gold‐deposited chip. In...
In this study, we developed a pore size/pore area-controlled optical biosensor-based anodic aluminum oxide (AAO) nanostructure. As the size of AAO increases, unit cell which also increases non-pore area to antibody binds. The increase in number antibodies immobilized on surface enables effective detection trace amounts antigen, because increased antigen-antibody bonding results larger refractive index change. High sensitivity was thus achieved through amplification interference wave two...
We proposed a novel white-light-emitting diode (LED) using the hybridization of quantum dots (QDs) blended with poly(9, 9-dioctylfluorenyl-2, 7-diyl) (PFO) as white emissive layer and poly(N-vinylcarbazole) (PVK) poly(N, N' -bis (4-butylphenyl)-N, N'-bis(phenyl) benzidine (poly-TPD) hole transport (HTL). The red- green-colored QDs CdSe ZnS core shell structure were mixed blue PFO to form hybrid layer, this generated pure light. analyzed performance characteristics white-LED function HTL...
We have developed a multi-array side-polished optical-fiber gas sensor for the detection of volatile organic compound (VOC) gases. The coupled with polymer planar waveguide (PWG) provides high sensitivity to alterations in refractive index. PWG was fabricated by coating solvatochromic dye poly(vinylpyrrolidone). To confirm effectiveness sensor, five different sensing membranes were using dyes Reinhardt’s dye, Nile red, 4-aminophthalimide, 4-amino-N-methylphthalimide, and...