A5087242352- Lymphoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- MicroRNA in disease regulation
- Colorectal Cancer Treatments and Studies
- Cancer-related molecular mechanisms research
- Pharmacological Effects of Natural Compounds
- Viral-associated cancers and disorders
- MRI in cancer diagnosis
- Air Quality and Health Impacts
- Urinary Bladder and Prostate Research
- Hormonal and reproductive studies
- Acute Lymphoblastic Leukemia research
- Microscopic Colitis
- Inflammatory Bowel Disease
- Diagnosis and treatment of tuberculosis
- Chronic Lymphocytic Leukemia Research
- Cancer Immunotherapy and Biomarkers
- Breast Lesions and Carcinomas
- Galectins and Cancer Biology
- Rheumatoid Arthritis Research and Therapies
- Chronic Kidney Disease and Diabetes
- CAR-T cell therapy research
- Thyroid and Parathyroid Surgery
- Energy and Environment Impacts
Second Military Medical University
2001-2025
Shanghai Pudong New Area Gongli Hospital
2001-2025
Union Hospital
2020-2024
Huazhong University of Science and Technology
2020-2024
First People’s Hospital of Zunyi
2017-2024
Chongqing Medical University
2022-2024
Shenzhen University
2023
Second Affiliated Hospital of Chongqing Medical University
2022-2023
Dalian Medical University
2022-2023
Sichuan University
2022
To evaluate the burden of air pollution on years life lost (YLL) in addition to mortality, we conducted a time series analysis based data pollution, meteorological conditions and 163,704 non-accidental deaths Ningbo, China, 2009-2013. The mean concentrations particulate matter with aerodynamic diameter <10 μm, <2.5 sulfur dioxide nitrogen were 84.0 μg/m(3), 60.1 25.1 μg/m(3) 41.7 respectively. An increase 10-μg/m(3) was associated 4.27 (95% confidence interval [CI] 1.17-7.38), 2.97 CI...
Purpose: To compare the efficacy of four different ultrasound-based risk-stratification systems in assessing malignancy risk thyroid nodules Chinese population. Methods: We retrospectively reviewed digital ultrasound images 1568 patients (1612 nodules) who underwent surgery our hospital between January 2012 and December 2017. All were pathologically identified as malignant or benign. evaluated following characteristics: size, location, composition, echogenicity, shape, margins, calcification...
Tumor-associated macrophages (TAMs) have been shown to be an essential component of the tumor microenvironment and facilitate proliferation invasion a variety malignancies. However, contribution TAMs meningioma progression has not characterized in detail. In this study, we aimed discover novel regulatory pathway by which exosome-mediated M2-polarized participate tumorigenesis progression. Methods. First, distribution functional phenotype tissues were assessed immunohistochemistry....
B cell activating factor (BAFF), a member of the tumor necrosis (TNF) family, plays critical role in pathogenesis and progression rheumatoid arthritis (RA). Chlorogenic acid (CGA) is phenolic compound exerts antiarthritic activities arthritis. However, it not clear whether anti-inflammatory property CGA associated with regulation BAFF expression. In this study, we found that treatment collagen-induced (CIA) mice significantly attenuated markedly inhibited production serum as well TNF-α....
Long non-coding RNA H19 (lncRNA-H19) is highly expressed in fibroblast-like synoviocytes (FLS) from patients with RA. The present study aimed to clarify the pathological significance and regulatory mechanisms of lncRNA-H19 FLS.Mice CIA were locally injected LV-shH19. progression was explored by measuring arthritic index (AI), paw thickness (PT) histologic analysis. growth cell cycle human synoviocyte MH7A assessed CCK-8 flow cytometric putative binding sites between miR-124a predicted...
Most of the current progression immune checkpoint inhibitors for malignant melanoma is based on data from Caucasians in Western countries, but benefit Chinese patients limited, mainly due to different pathological subtypes. The western countries are skin (about 90%), while acral and mucosal types dominant China, accounting 41.8% 22.6% respectively. Acral have lower response rates immunotherapy chemotherapy.
Dual-specificity phosphatase 5 (DUSP5) is a novel anti-inflammatory modulator in many inflammatory diseases. However, the role of DUSP5 fibroblast-like synoviocytes (FLS) rheumatoid arthritis (RA) remains unknown. In this study, we aimed to explore biological function and regulation FLS. We found that lower expression level was detected collagen-induced (CIA) synoviocyte MH7A. Overexpression markedly decreased proliferation, migration, invasion MH7A, which correlated with suppressing...
The commonly utilized phosphodiesterase type 5 inhibitors do not lead to satisfactory penile erection after radical prostatectomy mainly because of insufficient nitric oxide drive from the damaged cavernous nerves. aim this study was assess efficacy and mechanisms icariin in combination with daily sildenafil on neurogenic erectile dysfunction atrophy a rat model bilateral nerves injury. Sixty male Sprague-Dawley rats injected 5-ethynyl-2-deoxyuridine (50 mg/kg) at postnatal day 1 for purpose...
Non-small cell lung cancer (NSCLC) is one of the most fatal malignant tumors. Emerging studies have clarified crucial roles circular RNAs (circRNAs) in tumorigenesis cancers. CircVAPA was demonstrated to function some human The present study aimed investigate role circVAPA NSCLC. A quantitative real-time polymerase chain reaction used measure expression genes. Actinomycin D and RNase R were employed examine stability circVAPA. Cell-counting kit-8, 5-ethynyl-2'-deoxyuridine, Transwell sphere...
Background. Renal cell carcinoma is one of the most common malignant tumors in urinary system, seriously affecting people’s health and life. This study aimed to evaluate clinical value multi-mode color Doppler flow imaging for diagnosis solid renal tumor. Methods. Sixty-six from 63 patients were examined by (CDFI), power (PDFI), superb microvascular (SMI), contrast-enhanced ultrasound (CEUS) before surgery. The diagnostic efficacy four methods was compared determining blood grade ring-like...