A5041716030- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Advanced X-ray and CT Imaging
- Pancreatic and Hepatic Oncology Research
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Renal cell carcinoma treatment
- Metastasis and carcinoma case studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Surgical Treatments
- Hepatitis B Virus Studies
- Ultrasound and Hyperthermia Applications
- Ultrasound Imaging and Elastography
- Liver Diseases and Immunity
- Reproductive Biology and Fertility
- Colorectal and Anal Carcinomas
- Gallbladder and Bile Duct Disorders
- Nutrition and Health in Aging
- Animal Genetics and Reproduction
- Advanced MRI Techniques and Applications
- Appendicitis Diagnosis and Management
Seoul National University Bundang Hospital
2017-2025
Seoul National University
2017-2025
Seoul National University Hospital
2013-2017
National University College
2017
New Generation University College
2017
University of Ulsan
2016
Asan Medical Center
2016
Ulsan College
2016
Ewha Womans University
2016
Konkuk University
1994-2015
Model-based iterative reconstruction algorithms for low-dose X-ray computed tomography (CT) are computationally expensive. To address this problem, we recently proposed a deep convolutional neural network (CNN) CT and won the second place in 2016 AAPM Low-Dose Grand Challenge. However, some of textures were not fully recovered. here propose novel framelet-based denoising algorithm using wavelet residual which synergistically combines expressive power learning performance guarantee from...
The purpose of this study was to assess the image quality half-dose (HD) liver computed tomography (CT) using a model-based iterative reconstruction algorithm (MBIR) compared with reference dose (RD) filtered back projection (FBP) and HD CT images FBP adaptive statistical (ASIR).A total 103 patients suspected having metastases underwent including portal venous phase imaging. Among these patients, 73 had undergone RD reconstructed FBP, scans were separately MBIR. For other 30 ASIR,...
To develop and compare delta-radiomics signatures from 2- (2D) 3-dimensional (3D) features that predict treatment outcomes following preoperative chemoradiotherapy (CCRT) surgery for locally advanced rectal cancer.In total, 101 patients (training cohort, n = 67; validation 34) with adenocarcinoma between 2008 2015 were included. We extracted 55 T2-weighted magnetic resonance imaging (MRI) scans. Delta-radiomics feature was defined as the difference in radiomics before after CCRT. Signatures...
Abstract Silver nanoparticles (AgNPs) have many features that make them attractive as medical devices, especially in therapeutic agents and drug delivery systems. Here we introduced AgNPs into mouse spermatozoa then determined the cytotoxic effects of on sperm function subsequent embryo development. Scanning electron microscopy transmission analyses showed could be internalized cells. Furthermore, exposure to inhibited viability acrosome reaction a dose-dependent manner, whereas...
Objective: To compare the image quality of low-dose (LD) computed tomography (CT) obtained using a deep learning-based denoising algorithm (DLA) with LD CT images reconstructed filtered back projection (FBP) and advanced modeled iterative reconstruction (ADMIRE).Materials Methods: One hundred routine-dose (RD) abdominal studies FBP were used to train DLA.Simulated made at dose levels 13%, 25%, 50% RD (DLA-1, -2, -3) FBP.We trained DLAs simulated as input data ground truth.To test DLA,...
Purpose To evaluate the diagnostic performance of magnetic resonance (MR) elastography in staging liver fibrosis patients with chronic hepatitis B (CHB) and other etiologic causes. Materials Methods This retrospective study was institutional review board–approved requirement for informed consent waived. Before surgery, MR elastographic imaging performed 352 diseases (281 CHB, 71 without CHB) hepatocellular carcinomas 64 living donor candidates. Liver stiffness (LS) values were measured on...
Background Accurate assessment of local resectability pancreatic cancer at initial workup is critical to determine the most appropriate management strategy among up-front operation, neoadjuvant treatment, or palliative treatment. Purpose To investigate interobserver agreement preoperative CT classification and if radiologist experience level impacts evaluation, evaluate reader performance in assessing a subset patients with reference standard for resectability. Materials Methods This...
Few studies have been conducted on sex differences in the incidence, pathophysiology, and prognosis of gastric cancer (GC).To analyze GC characteristics according to patients who underwent surgical treatment for GC.A total 2983 diagnosed with adenocarcinoma received at Seoul National University Bundang Hospital between 2003 2017 were included. Baseline clinicopathological characteristics, histologic type GC, overall GC-specific survival rates, associated risk factors analyzed.Among patients,...
Background Noninvasive diagnostic guidelines for hepatocellular carcinoma (HCC) vary across different global geographic areas, especially regarding criteria about gadoxetic acid-enhanced MRI. Purpose To compare the performance of four international HCC diagnosis and readers' judgment in diagnosing using MRI patients at high risk HCC. Materials Methods This retrospective study included who had not undergone treatment, were HCC, underwent from January 2015 to June 2018 11 tertiary hospitals...
To evaluate the applicability, reproducibility, and diagnostic performance of a new 2D-shear wave elastography (SWE) using comb-push technique (2D CP-SWE) for detection hepatic fibrosis, histopathology as reference standard.This prospective study was approved by institutional review board, informed consent obtained from all patients. The liver stiffness (LS) measurements were 140 patients, 2D-SWE, which uses excitation to produce shear waves time-aligned sequential tracking method detect...
BackgroundThe performance of PET/MRI in the determination distant metastases (M stage) rectal cancer relative to current practice with contrast material-enhanced CT is largely unknown.PurposeTo compare staging clinical M stage fluorine 18 fluorodeoxyglucose (FDG) (including dedicated liver and MRI) that chest abdominopelvic MRI.Materials MethodsFrom January 2016 August 2017, patients newly diagnosed advanced mid low cancers were recruited for this prospective study (clinicaltrials.gov...
Objectives The aim of this study was to investigate the clinical feasibility simultaneous reduction radiation and contrast doses using spectral computed tomography (CT) in patients at high-risk for hepatocellular carcinoma. Materials Methods Between May 2017 March 2018, prospective recruited participants risk carcinoma with body mass indexes less than 30 randomly assigned them either standard-dose group or double low-dose group, which targeted 30% reductions both media (NCT03045445). Lesion...
The purpose of the study was to investigate clinical feasibility free-breathing dynamic T1-weighted imaging (T1WI) using Cartesian sampling, compressed sensing, and iterative reconstruction in gadoxetic acid-enhanced liver magnetic resonance (MRI).This retrospective approved by our institutional review board, requirement for informed consent waived. A total 51 patients at high risk breath-holding failure underwent T1WI a manner volumetric interpolated breath-hold (BH) examination with...
To survey experts' opinions in abdominal radiology (radiologists) and pancreas-specialized gastroenterology (pancreatologists) South Korea regarding diagnosing managing pancreatic cystic neoplasms (PCNs).
To retrospectively investigate whether texture features obtained from preoperative CT images of advanced gastric cancer (AGC) patients could be used for the prediction occult peritoneal carcinomatosis (PC) detected during operation.51 AGC with PC operation January 2009 to December 2012 were included as group. For control group, other 51 without evidence distant metastasis including PC, and whose clinical T N stage matched those selected period 2011 July 2012. Each group was divided into test...
Elastography point quantification is a convenient method for measuring liver stiffness. It can be performed simultaneously with conventional ultrasonography. This study aimed to evaluate its diagnostic performance assessing hepatic fibrosis in patients autoimmune disease (AILD), including hepatitis (AIH) and primary biliary cholangitis (PBC).The of elastography (ElastPQ) was evaluated compared that serum markers, the aspartate aminotransferase platelet ratio index (APRI) fibrosis-4 (FIB-4),...
To evaluate the feasibility, efficiency, and safety of no-touch switching bipolar (SB) monopolar (SM) radiofrequency ablation (RFA) using ex vivo bovine livers. A pork loin cube was inserted as a tumor mimicker in liver block; RFA performed technique SM (group A1; 10 minutes, n = 10, group A2; 15 10) SB B; modes. The groups were compared based on creation confluent necrosis with sufficient margins, dimensions, distance between electrode zone margin (DEM). safety, small bowel loops placed...
Objective To evaluate the in vivo technical feasibility, efficiency, and safety of switching bipolar (SB) monopolar (SM) radiofrequency ablation (RFA) as a no-touch technique porcine liver. Materials methods The animal care use committee approved this study 16 pigs were used two independent experiments. In first experiment, RFA was performed on 2-cm tumor mimickers liver using SM mode (2 groups, SM1: 10 minutes, n = 10; SM2: 15 10) SB-mode (1 group, SB: 10). success with sufficient margins,...
To assess intra- and inter-observer reproducibility of a new point shear wave elastography technique (pSWE, S-Shearwave, Samsung Medison) compare its accuracy in assessing liver stiffness (LS) with an established pSWE (Virtual Touch Quantification, VTQ).Thirty-three patients were enrolled this Institutional Review Board-approved prospective study. LS values measured by VTQ on Acuson S2000 system (Siemens Healthineer) S-Shearwave RS-80A (Samsung the same session, followed two further sessions...