Zixiao Zhang

ORCID: 0000-0001-7404-4573
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Research Areas
  • Orbital Angular Momentum in Optics
  • Advanced Image and Video Retrieval Techniques
  • Cancer-related molecular mechanisms research
  • Domain Adaptation and Few-Shot Learning
  • Microfluidic and Bio-sensing Technologies
  • Near-Field Optical Microscopy
  • Machine Learning in Bioinformatics
  • Advanced Neural Network Applications
  • Genomics and Phylogenetic Studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Advanced Antenna and Metasurface Technologies
  • Epigenetics and DNA Methylation
  • Human Pose and Action Recognition
  • Hemodynamic Monitoring and Therapy
  • Sperm and Testicular Function
  • Video Surveillance and Tracking Methods
  • Ferroptosis and cancer prognosis
  • Autopsy Techniques and Outcomes
  • Metamaterials and Metasurfaces Applications
  • Trauma and Emergency Care Studies
  • RNA and protein synthesis mechanisms
  • Non-Invasive Vital Sign Monitoring
  • Emotion and Mood Recognition
  • RNA modifications and cancer
  • Scoliosis diagnosis and treatment

Third Affiliated Hospital of Sun Yat-sen University
2025

Sun Yat-sen University
2025

Peking University People's Hospital
2020-2024

Institute of Biophysics
2024

Chinese Academy of Sciences
2024

Wuxi People's Hospital
2020-2024

Nanjing Medical University
2010-2024

Huazhong University of Science and Technology
2016-2024

Peking University
2017-2024

University of Chinese Academy of Sciences
2024

Drone captured images have overwhelming characteristics including dramatic scale variance, complicated background filled with distractors, and flexible viewpoints, which pose enormous challenges for general object detectors based on common convolutional networks. Recently, the design of vision backbone architectures that use self-attention is an exciting topic. In this work, improved MHSA-Darknet designed to retain sufficient global context information extract more differentiated features...

10.1109/iccvw54120.2021.00314 article EN 2021-10-01

Object detection on the drone faces a great diversity of challenges such as small object inference, background clutter and wide viewpoint. In contrast to traditional problem in computer vision, bird-like angle can not be transplanted directly from common-in-use methods due special texture sky's view. However, lack comprehensive data set, number algorithms that focus using captured by drones is limited. So VisDrone team gathered massive set organized Vision Meets Drones: A Challenge...

10.1109/iccvw54120.2021.00319 article EN 2021-10-01

For visual question answering on remote sensing (RSVQA), current methods scarcely consider geospatial objects typically with large-scale differences and positional sensitive properties. Besides, modeling reasoning the relationships between entities have rarely been explored, which leads to one-sided inaccurate answer predictions. In this article, a novel method called spatial hierarchical network (SHRNet) is proposed, endows (RS) (VQA) system enhanced visual–spatial capability. Specifically,...

10.1109/tgrs.2023.3237606 article EN IEEE Transactions on Geoscience and Remote Sensing 2023-01-01

Circadian rhythm misalignment due to social jet lag, shift work, early morning starts, and delayed bedtimes is becoming common in our modern society. Disturbances of sleep the underlying circadian rhythms are related multiple human diseases, such as obesity, diabetes, cardiovascular disorders, cognitive impairments. Given crucial role microbiota same pathologies caused by disturbance, how gut affected increasing interest. The results this study indicate that acute disturbance sleep-wake...

10.1128/msphere.00914-19 article EN cc-by mSphere 2020-02-11

Macrophage polarization plays an important role in the pathogenesis of COPD emphysema. Changes macrophage remain unclear, while and ferroptosis are essential factors its pathogenesis. Therefore, this study investigated relationship between emphysema.We measured levels matrix metalloproteinases (MMPs) lung tissues patients cigarette smoke (CS)-exposed mice. Flow cytometry was used to determine (THP-M cell) changes. Ferroptosis examined by FerroOrange, Perls' DAB, C11-BODIPY 4-HNE staining....

10.2147/copd.s354896 article EN cc-by-nc International Journal of COPD 2022-03-01

Nuclear factor E2-related 2 (Nrf2) is involved in oxidative stress and lung inflammation regulates the etiology of chronic obstructive pulmonary disease (COPD). Ferroptosis characterized by accumulation lipid reactive oxygen species (ROS) via ferrous ion-dependent Fenton reactions COPD. However, role Nrf2 ferroptosis its epigenetic regulation pathogenesis COPD remain unclear.Ferroptosis was detected 4-HNE, MDA, C11BODIPY, DCFH-DA, Peals' staining CCK-8 assays. qPCR Western blotting were...

10.2147/copd.s340113 article EN cc-by-nc International Journal of COPD 2021-12-01

As a fundamental task for research in satellite videos (SVs), object tracking is used to track the target of interest traffic evaluation, military security, and so forth. The current technology remote sensing field makes it possible moving targets with relatively high frame rate image resolution. However, objects under this special view are often small blurry, making hard extract deep features effectively. result, quite few learning (DL) methods were proposed SVs. In addition, evaluation...

10.1109/mgrs.2022.3198643 article EN IEEE Geoscience and Remote Sensing Magazine 2022-09-02

Promoters play an irreplaceable role in biological processes and genetics, which are responsible for stimulating the transcription expression of specific genes. Promoter abnormalities have been found some diseases, level promoter-binding factors can be used as a marker before disease occurs. Hence, detecting promoters from DNA sequences has important significance, particular, distinguishing strong help to elucidate differences gene mechanisms diseases. With introduction third-generation...

10.1016/j.ymeth.2022.01.001 article EN cc-by-nc-nd Methods 2022-01-05

Electrocatalytic processes occurring at the heterogeneous interface are complex and their understanding molecular level remains challenging. Atomic force microscope (AFM) can detect interactions down to atomic level, but so far it has been mainly used obtain in-situ images of electrocatalysts. Here for first time, we employ AFM investigate gas evolution a platinum ultramicroelectrode (Pt UME) under electrochemical conditions using noise method. We excess when individual H2 bubble nucleation,...

10.48550/arxiv.2501.03159 preprint EN arXiv (Cornell University) 2025-01-06

Introduction: Circulating tumor cells (CTCs) are important prognostic indicators for malignancies. However, a reliable positive/negative cutoff value of non-epithelial (NE+: hybrid and mesenchymal) CTCs phenotype in prostate cancer (PCa) patients has not been established. Here, we aimed to determine the NE+ high-risk (HRPC) after radical prostatectomy (RP). Methods: The was established spiking experiments, were detected 208 HRPC using CanPatrolTM platform. expression function COL1A1 PCa...

10.7150/ijms.107703 article EN cc-by-nc International Journal of Medical Sciences 2025-02-28

In order to improve the channel capacity, waves carrying orbital angular momentum (OAM) in communication systems have attracted much attention. A two-OAM-mode antenna system, which works at 2.4 GHz, is proposed this paper. And a signal transmission experiment performed based on pair of systems. The has planar structure, composed two patch arrays, feeding networks, and one common ground plane. Then, reflection coefficients, radiation patterns, phase distributions system are measured,...

10.1109/access.2018.2886553 article EN cc-by-nc-nd IEEE Access 2018-12-13

In this letter, two simple and novel circular slot antenna systems to generate OAM waves are proposed. Special feeding networks, which can be used modes, designed at 2.4 GHz feed the antenna. Furthermore, fabricated tested. Both simulation measurement results demonstrate effectiveness of for generating waves.

10.1109/lawp.2016.2641458 article EN IEEE Antennas and Wireless Propagation Letters 2016-12-19

Abstract Background Establishment of a mouse model is important for investigating the mechanism chronic obstructive pulmonary disease (COPD). In this study, we observed and compared evolution pathology in two models COPD induced by cigarette smoke (CS) exposure alone or combination with lipopolysaccharide (LPS). Methods One hundred eight wild-type C57BL/6 mice were equally divided into three groups: (1) control group, (2) CS-exposed group (CS group), (3) CS + LPS-exposed LPS group). The body...

10.1186/s12890-021-01456-z article EN cc-by BMC Pulmonary Medicine 2021-04-26

Abstract Background Myofibroblast differentiation and extracellular matrix (ECM) deposition are observed in chronic obstructive pulmonary disease (COPD). However, the mechanisms of regulation myofibroblast remain unclear. Materials methods We detected let‐7 levels peripheral lung tissues, serum primary bronchial epithelial cells COPD patients cigarette smoke (CS)‐exposed mice. IL‐6 mRNA was explored tissues CS‐exposed protein cell supernatant from by ELISA. confirmed regulatory effect on...

10.1111/eci.13425 article EN cc-by-nc-nd European Journal of Clinical Investigation 2020-10-10

This study sought to explore the underlying mechanism of miR-21 mediated apoptosis and inflammation in chronic obstructive pulmonary disease (COPD) induced by cigarette smoke (CS).

10.2147/copd.s453593 article EN cc-by-nc International Journal of COPD 2024-05-01

Stroke is a long-term disability and one of the leading causes death. However, no successful therapeutic intervention available for majority stroke patients. In this study, we explored traditional Chinese medicine Baifuzi (Typhonium giganteum Engl.). We show, at first, that ethanol extract exerts neuroprotective effects against brain damage induced by transient global or focal cerebral ischemia in rats mice. Second, activated large-conductance Ca(2+)-activated K(+) channel (BK(Ca)) channels,...

10.1038/cddis.2009.10 article EN cc-by Cell Death and Disease 2010-01-21

Dental pulp stem cells (DPSCs) constitute a unique group of endowed with multipotency, self-renewal, and capacity to regenerate the dental tissue. While much has been learned about these in recent years, it is still unclear if each DPSC multipotent or sub-populations DPSCs are “primed” undergo specific differentiation paths. The purpose present study was define whether sub-population uniquely primed vasculogenic differentiation. Permanent-tooth from human exfoliated deciduous teeth (SHED)...

10.22203/ecm.v041a21 article EN European Cells and Materials 2021-03-16

ABSTRACT Background Lead (Pb) has become one of the most dangerous metals to human health, especially nervous system as its persistent accumulation and high toxicity. However, how gut microbiota influence Pb‐related neurotoxicity remains unclear. The aim our study was explore link among Pb exposure, behavior changes, microbiota. Methods Using Drosophila melanogaster model, climbing assay, social avoidance, space, short‐term memory analysis were preformed behavioral changes in flies exposed...

10.1002/jdn.10067 article EN International Journal of Developmental Neuroscience 2020-09-23

Antenna array is one of the methods which can generate Orbital Angular Momentum (OAM) waves. However, OAM waves generated by different antenna arrays have characteristics Electric-field (E-field) components' distribution and radiation patterns. In order to solve this problem, we derive E-field formulas kinds dipole in paper. The are arranged three methods: 1) elements same direction y axis, 2) radial 3) azimuthal direction. Results show that x components, components z carry modes under...

10.1016/j.dcan.2020.09.009 article EN cc-by-nc-nd Digital Communications and Networks 2020-11-12

Abstract Purpose The “normal” cervical spine may be non-lordotic shapes and the alignment targets are less well established. So, study was to propose novel classification for morphologies with Chinese asymptomatic subjects, address balance status based on classification. Method An overall 632 individuals were selected from January 2020 December 2022, six age groups 20–30 year 70 plus group. Cervical contained C2-7 lordosis (C2-7 CL) T1 slope (T1S), together C1-2 CL, C2-4 C5-7 C2S, sagittal...

10.1007/s00586-023-07997-7 article EN cc-by European Spine Journal 2023-10-25

Vesicular transport proteins are related to many human diseases, and they threaten health when undergo pathological changes. Protein function prediction has been one of the most in-depth topics in bioinformatics. In this work, we developed a useful tool identify vesicular proteins. Our strategy is extract transition probability composition, autocovariance transformation other information from position-specific scoring matrix as feature vectors. EditedNearesNeighbours (ENN) used address...

10.3389/fgene.2021.808856 article EN cc-by Frontiers in Genetics 2022-01-03

The Q235 steel plate butt joint was successfully welded by the laser K-TIG hybrid welding method. effects of process parameters such as current, distance between heat sources, power, defocusing amount, and speed on coupled arc profile stability were studied. results indicated that deflects arc, deflection angle becomes smaller current increases. After generates small holes, if beam acts bottom keyhole, depth can be further increased; however, power has little effect depth. sources is main...

10.3390/met12071139 article EN cc-by Metals 2022-07-03
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