A5100733254- Dermatologic Treatments and Research
- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- Adaptive optics and wavefront sensing
- Optical Systems and Laser Technology
- Nonmelanoma Skin Cancer Studies
- Nail Diseases and Treatments
- Hair Growth and Disorders
- Contact Dermatitis and Allergies
- Tumors and Oncological Cases
- Laser Applications in Dentistry and Medicine
- Acute Myeloid Leukemia Research
- Vascular Tumors and Angiosarcomas
- Dermatological and COVID-19 studies
- Acne and Rosacea Treatments and Effects
- melanin and skin pigmentation
- Dermatology and Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Autoimmune Bullous Skin Diseases
- Sarcoma Diagnosis and Treatment
- Chemotherapy-related skin toxicity
- Facial Rejuvenation and Surgery Techniques
- Hematological disorders and diagnostics
- Bone and Joint Diseases
- Drug-Induced Adverse Reactions
Sungkyunkwan University
2015-2025
Kangbuk Samsung Hospital
2013-2025
Konyang University
2025
Gwangju National University of Education
2024
Chonnam National University
2016-2024
Changshin University
2023
Kyungpook National University
2022-2023
Korea Astronomy and Space Science Institute
2023
Samsung (South Korea)
2016-2021
Kangwon National University
2018
Abstract Background Female pattern hair loss (FPHL) is the most common cause of in women, and its prevalence increases with advancing age. Affected women may experience psychological distress social withdrawal. A variety laser light sources have been tried for treatment loss, some success has reported. Objective The purpose this study was to determine efficacy safety a 1550 nm fractional erbium–glass female loss. Patients methods Twenty eight ethnic South Korean patients varying degrees FPHL...
BackgroundDuring the coronavirus disease 2019 (COVID‐19) pandemic, various adverse skin reactions to long‐term mask wearing have been reported.
In this study, the anti-inflammatory effect of hot water extract Endarachne binghamiae (EB-WE), a type marine brown algae, was investigated in LPS-stimulated RAW 264.7 cells and an acute lung injury (ALI) mouse model induced by intranasal LPS administration. Treatment with EB-WE significantly inhibited NO pro-inflammatory cytokine (TNF-a IL-6) production cells. mRNA analysis, expression cytokines, COX-2, iNOS mRNAs, down-regulated treatment. The phosphorylation MAPK, IkB, PI3K/AKT molecules...
Comprehensive studies on the tumor burden of soft-tissue sarcoma (STS) by anatomical site are lacking in Asian populations. To investigate distribution STS via relative density (RTD) a Korean cohort. The RTDs patients with at single-institution from 2007-2022 were retrospectively analyzed. describe locations, body was divided into 4 sites, and RTD each calculated to compare topographic burden. Fifty-nine cases 58 individuals, 35 male (60.3%) 23 female (39.7%), mean age 56.5±20.4 Overall,...
Prediction of whether postoperative wound healing will result in a hypertrophic scar or keloid is difficult. Diverse treatment options have been developed an effort to prevent excessive formation.To evaluate the efficacy and safety 532-nm potassium titanyl phosphate (KTP) laser prevention formation after total thyroidectomy.Twenty-eight individuals with Fitzpatrick skin types IV V linear surgical suture lines thyroidectomy by same surgeon were enrolled. Twenty participants treated using KTP...
Panax ginseng has been used to prolong longevity and is believed be useful for improving skin complexion. Ginsenosides are the most active components isolated from ginseng, ginsenoside Rg3 (G-Rg3) in particular demonstrated possess antioxidative, antitumorigenic, anti-inflammatory properties. The aim of this study was examine ability G-Rg3 inhibit melanogenesis.The effects on melanin contents protein levels tyrosinase, microphthalmia-associated transcription factor (MITF), tyrosinase-related...
Photoactivation of flavins is coupled productively with the direct transfer photoinduced electrons to P450s achieve photobiocatalytic C-hydroxylation reactions in absence nicotinamide cofactors.
Abstract Background Pigmented contact dermatitis (PCD), a rare variant of non‐eczematous dermatitis, is clinically characterized by sudden‐onset brown or grey pigmentation on the face and neck. It hypothesized to be caused repeated with low levels allergens. Objectives This study evaluated risk using hair dyes in patients PCD Korea. Methods A total 1033 1366 controls from 31 university hospitals were retrospectively recruited. We collected analysed data patient group, diagnosed through...
Abstract As many new cosmetic products are introduced into the market, attention must be given to contact dermatitis, which is commonly caused by cosmetics. We investigate prevalence of preservative allergy in 584 patients with suspected dermatitis at 11 different hospitals. From January 2010 March 2011, hospital dermatology departments presented symptoms. These were patch‐tested for allergens. An irritancy patch test performed on 30 control subjects using allergens various concentrations...
Background: The present controlled study assessed the systemic effect of 830-nm LED phototherapy in rodent models. Materials and methods: Two HR-1 hairless mice 3 HWY/Slc rats were divided into two groups: treatment group (Tx Group, one mouse, rats) control (Con rat). All animals received an identical 12 mm × burn over three sites on dorsum with a fractional ablative CO2 laser. Wounds protected film-type dressing. abdomen Tx Group subjects was irradiated array immediately post then at 1, 5 6...
Background: Currently no study has evaluated the effect of novel 1064–nm picosecond neodymium-doped:yttrium aluminium garnet laser (ps–Nd:YAG) for reducing Hypertrophic scarring (HS). Objective: The aim this was to verify efficacy and safety a 1064-nm ps-Nd:YAG in management HS. Materials Methods: A retrospective chart review photographic analysis were conducted on patients treated with low-fluence HS improvement. Vancouver Scar Scale (VSS), 5-point Global Assessment Score (GAS), patient...
BACKGROUND The pigmentary disorders including melasma, freckles, postinflammatory hyperpigmentation, or acquired bilateral nevus of Ota-like macules, etc. are usually resistant to all treatment modalities, and therefore very frustrating the patient clinician. OBJECTIVE purpose this study was demonstrate effect combination recalcitrant with pigmented laser chemical peeling observe any side-effects. METHODS Twenty-four patients facial were treated Q-switched alexandrite at fluences 7.0–8.0...
Mycobacterium abscessus (M.abscessus) is an acid-fast bacillus that's classified as a pathogenic "rapid growing" nontuberculous mycobacteria.It uncommon cause of human disease, but it can skin and soft tissue infection after injury following inoculation, minor trauma surgery.The single most important factor for determining the course prognosis M. underlying immune status host.We report here on 71-year-old female who presented with multiple painful erythematous cutaneous nodules her left...
Background Vivax malaria was successfully eliminated in the Republic of Korea (South Korea) late 1970s, but it found to have re-emerged from 1993. In order control and evaluate effectiveness controls, is important develop a spatiotemporal understanding genetic structure parasite population. Here, we estimated population temporal dynamics transmission Plasmodium vivax South by analyzing microsatellite DNA markers parasite. Methodology/Principal Findings We analyzed 14 loci P. genome 163...
Abstract Background Various options such as surgical excision, steroid injection, cryotherapy, pressure dressing, and radiation therapy are available for the treatment of auricular keloids. In particular, keloid using excision is important because recurrence rates low compared with keloids occurring in other parts body. Aims We aimed to evaluate clinical outcomes intralesional followed by postoperative triamcinolone acetonide injection (TA ILI) treatments. Methods conducted a surgery records...
Mannitol containing monophasic filler with higher crosslinking has not been well studied for moderate and severe nasolabial fold (NLF) correction.To compare the efficacy safety of a novel mannitol hyaluronic acid (HA) (HA-G) biphasic HA (HA-P) NLF correction.Thirteen subjects symmetric to received HA-G (in one NLF) HA-P other were evaluated 24 weeks.At both 12 weeks, mean improvement in Genzyme 6-point grading scale from baseline was significantly greater side face that treated than...
Abstract A building block containing eight zincs and iodo groups (8 Zn) is obtained by the Zn complexation of a salen ligand bearing two additional hydroxy groups. Through Sonogashira–Hagihara coupling 8 with 1,3,5,7‐tetra(4‐ethynylphenyl) adamantane, microporous organic polymers octanuclear zinc clusters (MOP‐8 are prepared, exhibiting high surface area 562 m 2 g −1 , microporosity, particulate morphology an average diameter 249 nm. The MOP‐8 exhibits significantly enhanced catalytic...
ABSTRACT Background/Objectives There are scant established data on the cause, distribution, treatment options, and recurrence rate of pediatric keloids in Asian populations. We characterized clinical features by comprehensively categorizing keloid patients into prepubertal postpubertal groups at a single tertiary center. Methods searched database Kangbuk Samsung Hospital for (< 18 years) with clinically proven who underwent outpatient‐based from 2007 to 2021. Clinical features, including...
Dear Editor: Cutaneous pili migrans is a rare skin condition in which hair shaft or fragment embedded the superficial skin. It characterized by creeping eruption with black-line like mimicking cutaneous larva migrans1. Removal of black heals lesion completely2,3. Herein, we report case clinical and histopathological findings. A 46-year-old Korean man presented 3-week history asymptomatic linear along crease neck. A thin black, thread-like line resembling was below epidermis. He had no...
Pleomorphic dermal sarcoma (PDS) is a rare mesenchymal neoplasm sharing histopathological features with atypical fibroxanthoma (AFX), but has additional of deep invasion the superficial subcutis, tumor necrosis and vascular/perineural invasion. It not well documented in literature because its rarity, clinical course been debated due to lack homogenous criteria. We describe here case 91-year-old female 6-month history solitary, asymptomatic, well-defined, 3.4-cm-sized, reddish, hard,...
Streptomyces avermitilis produces clinically useful drugs such as avermectins and oligomycins. Its genome contains approximately 33 cytochrome P450 genes they seem to play important roles in the biosynthesis of many secondary metabolites. The SAV_7130 gene from S. encodes CYP158A3. amino acid sequence this enzyme has high similarity with that CYP158A2, a biflaviolin synthase coelicolor A3(2). Recombinant CYP158A3 was heterologously expressed purified. It exhibited typical Soret peak at 447...
Low fluence 1,064 nm Q-switched (QS) Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) laser treatment, also known as toning, is widely used for pigmentary disorders. There has been no reliable evaluation of the effect low QS Nd:YAG senile lentigo.To investigate beneficial in treatment lentigo on face.A retrospective review was conducted patients treated only with repetitive laser. Among them, 12 multiple lentigines before were included. All side effects recorded to assess safety modality.Mean age...
Eccrine hidrocystomas are small benign cystic lesions that normally affect only adult females. hidrocystoma is characterized by tense vesicles predominately located on the face and particularly periorbital areas. Histologically, eccrine consists of one or more partially collapsed unilocular cysts in dermis, these often situated adjacent to normal ducts. An 8-year-old boy presented with multiple skin-colored bluish tiny papules his nose. Histopathologically, dilated partial structures...
Background: Recently, the efficacy of autologous plasma filler for reduction facial wrinkles has been demonstrated. Objective: The aim our study is to validate and safety in treating nasolabial fold wrinkles. Material methods: Twenty Korean patients with moderate-to-severe were enrolled. treated one session filler. wrinkle improvement effects evaluated at 1-week, 4-week, 8-week, 12-week after treatment. Three assessment methods applied. First, two independent dermatologists assessed cosmetic...