A5003430282- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Head and Neck Surgical Oncology
- Brain Metastases and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- COVID-19 diagnosis using AI
- Radiation Dose and Imaging
- Hematological disorders and diagnostics
- Meningioma and schwannoma management
- Neuroendocrine Tumor Research Advances
- Neutropenia and Cancer Infections
- Medical Imaging Techniques and Applications
- Oral health in cancer treatment
- Pelvic and Acetabular Injuries
- Pituitary Gland Disorders and Treatments
- Soft tissue tumor case studies
- Sinusitis and nasal conditions
- Reconstructive Surgery and Microvascular Techniques
- Artificial Intelligence in Healthcare and Education
Tata Memorial Hospital
2021-2025
Homi Bhabha National Institute
2022-2025
Paras Hospitals
2025
Clatterbridge Cancer Centre NHS Foundation Trust
2022-2023
Creative Commons
2023
Vardhman Mahavir Medical College & Safdarjung Hospital
2023
Clínica Ruiz
2023
Purpose: The authors aimed to develop and validate deep-learning-based radiogenomic (DLR) models radiomic signatures predict the EGFR mutation in patients with NSCLC, assess semantic clinical features that can contribute detecting mutations. Methods: Using 990 from two NSCLC trials, we employed an end-to-end pipeline analyzing CT images without precise segmentation. Two 3D convolutional neural networks segmented lung masses nodules. Results: combined radiomics DLR model achieved AUC of 0.88...
Precise detection and characterization of pulmonary nodules on computed tomography (CT) is crucial for early diagnosis management. In this study, we propose the use a deep learning-based algorithm to automatically detect in scans. We evaluated performance against interpretation radiologists analyze effectiveness algorithm. The study was conducted collaboration with tertiary cancer center. used collection public (LUNA) private (tertiary center) datasets train our learning models. sensitivity,...
According to the 8th edition of American Joint Committee on Cancer (AJCC), involvement masticator space and infratemporal fossa (ITF) in oral cancers indicates advanced disease (T4b), which is often considered unresectable. Previous studies have shown that extent ITF influences management outcomes. Therefore, optimize management, T4b should be subclassified based involvement. Notably, infranotch has a more favorable prognosis compared supranotch disease. Our study also observed certain...
Bhatter, Pallav; Gupta, Vipul; Kumar, Rao, Dusa Srinivas; Agarwal, Ujjwal; Parthasarathy, Rajsrinivas Author Information
Objective Extra Nodal Extension (ENE) assessment in locally advanced head and neck cancers (LAHNCC) treated with concurrent chemo radiotherapy (CCRT) is challenging hence the American Joint Committee on Cancer (AJCC) N staging. We hypothesized that radiology-based ENE (rENE) may directly impact outcomes LAHNSCC radical CCRT. Materials Methods Open-label, investigator-initiated, randomized controlled trial (RCT) (2012–2018), which included planned for Patients were 1:1 to (66–70 grays) weekly...
The aim of this study was to investigate the feasibility developing a deep learning (DL) algorithm for classifying brain metastases from non-small cell lung cancer (NSCLC) into epidermal growth factor receptor (
Although CT and MRI are crucial imaging modalities for the preoperative staging surgical planning of head neck tumors, quality reports, as well adequate methodology, equally critical. The content report, proper communication these findings to treating physicians important determinants optimal patient care. Synoptic reporting is a method presenting specified data pieces in predetermined format. When compared random reporting, synoptic gives standardized information less time. It enables more...
Abstract Oral cavity cancers contribute to a majority of in India. Clinical examination alone cannot determine the deeper extent disease; therefore, need for cross-sectional imaging including computed tomography and magnetic resonance becomes indispensable pre-treatment evaluation decide optimal plan management. squamous cell (OSCC) can be treated with surgery alone, whereas deep muscle, neurovascular, osseous, or nodal involvement on suggests advanced disease that requires combination...
To study the pattern of mandibular involvement and its impact on oncologic outcomes in patients with gingivo-buccal complex squamous cell carcinoma (GBC-SCC) propose a staging system based bone (MMC: Marrow canal system) compare performance 8th edition American Joint Committee Cancer (AJCC8).This retrospective observational included treatment-naïve GBC-SCC who underwent preoperative computed tomography (CT) imaging between January 1, 2012, March 31, 2016, at tertiary care cancer center....
According to the American Joint Committee on Cancer (AJCC) eighth edition, involvement of masticator space and infratemporal fossa (ITF) by oral cancer signifies advanced disease (T4b), which is most often deemed unresectable. The extent ITF impacts management outcomes. T4b needs be subclassified for optimal management. with infra-notch extension associated a favorable prognosis compared supra-notch disease. Certain cases may potentially converted resectable following neoadjuvant...
Abstract We discussed the imaging recommendations for diagnosis, staging, and management of larynx hypopharynx cancer. Carcinoma is a common cancer, with males being affected more. Hypopharyngeal carcinoma less than laryngeal malignancies. Squamous cell most histological type. Nonsquamous malignant lesions are rare mostly submucosal lesions. Clinical examination endoscopy play an integral role in its detection staging. Imaging also plays major including local disease extent, nodal distant...
Abstract Thyroid cancer ranks as the leading endocrine malignancy in adults. The foundation for primary diagnosis of thyroid is a high-resolution ultrasound (US) gland including US-guided fine-needle biopsy (FNB) suspected nodules. Advanced cross-sectional imaging, computed tomography (CT), magnetic resonance and positron emission tomography, can be useful selected patients. mainstay treatment surgery. It may supplemented by radioactive iodine ablation/therapy high-risk differentiated...
Posterior reversible encephalopathy syndrome (PRES) is a disorder of subcortical vasogenic brain oedema in patients with acute neurological symptoms. Drug-induced PRES has been described the usage drugs that target receptors regulating vascular permeability or altering immune response. Lenvatinib receptor tyrosine kinase inhibitor inhibits activities endothelial growth factor implicated cancer progression addition to their normal cellular functions. The associated consequence disruption...
Extrathyroidal extension (ETE) is the term used to describe growth of primary thyroid tumor beyond capsule. ETE a critical prognostic marker for tumors, necessitating accurate preoperative assessment. This study aims evaluate diagnostic performance computed tomography (CT)-based grading and tracheal invasion (TI) prediction in patients with differentiated papillary carcinoma (PTC) compare accuracy ultrasound (US).
ABSTRACT Background: Patients with medical imaging performed and interpreted elsewhere often come to tertiary referral centers for further management. At our cancer hospital, external studies of patients head-and-neck undergo formal second opinion reporting by subspecialty oncoradiologists. Objectives: We aimed audit the in-house review outside scans specialized radiologists estimate potential impact on patient Our secondary objective was determine direct specialist change in diagnosis,...
Abstract With an increasing rate of cancers in almost all age groups and advanced screening techniques leading to early diagnosis longer longevity patients with cancers, it is utmost importance that radiologists assigned cancer imaging should be prepared deal specific expected unexpected circumstances may arise during the lifetime these patients. Tailored integration preventive curative interventions current health plans global escalation efforts for timely will pave path a cancer-free...
Abstract The percutaneous needle biopsy (PNB) is the initial step for obtaining diagnosis and it helps in treatment. It aids primary diagnosis, tumor staging, or ruling out infective etiology. a safe successful minimally invasive method compared to open biopsies. PNB defined as placement insertion of into suspected lesion organ with intent retrieving tissue cells diagnosis. can fine aspiration cytology core biopsy. patient needs be counseled regarding procedure detailed history, including...
Aim: Early diagnosis of paediatric brain tumors significantly improves the outcome. The aim is to study magnetic resonance imaging (MRI) features and develop an automated segmentation (AS) tool which could segment classify using deep learning methods compare with radiologist assessment. Methods: This included 94 cases, 75 were diagnosed cases ependymoma, medulloblastoma, brainstem glioma, pilocytic astrocytoma 19 normal MRI cases. data was randomized into training data, 64 cases; test 21...
Interpreting complex post-treatment changes in head and neck cancer (HNC) is challenging with further added perplexity due to variable interobserver interpretation hence evolved the NI-RADS lexicon. We evaluated accuracy of predicting disease status on 1st follow-up CECT a homogenous cohort those who received only chemoradiation.Retrospective analysis imaging was done for LASHNC patients radical chemoradiation an open-label, investigator-initiated, phase 3 randomized trial (2012-2018)...
Aim: Sarcopenia and skeletal muscle density (SMD) have been shown to be both predictive prognostic marker in oncology. Advanced lung cancer inflammation index (ALI) has predict overall survival (OS) small cell (SCLC). Computed tomography (CT) enables quantified, whereas body mass (BMI) cannot accurately reflect composition. The purpose was evaluate the value of modified ALI (mALI) using CT-determined third lumbar vertebra (L3) beyond original see interaction between sarcopenia, SMD,...
Preoperative imaging is essential for staging carcinomas of the oral tongue in addition to clinical staging. The current TNM cavity according 8 th edition American Joint Committee on Cancer appropriate buccal mucosal due their proximity and frequent involvement skin, bone, masticator space case advanced disease. However, it inadequate subclassification carcinomas. Tongue cancers, even those stage, do not frequently involve these structures, thus leading understaging tumors. We observed that...