Lutz Bachmann

ORCID: 0000-0001-7451-2074
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About
Contact & Profiles
Research Areas
  • Marine animal studies overview
  • Parasite Biology and Host Interactions
  • Genetic diversity and population structure
  • Genomics and Phylogenetic Studies
  • Chromosomal and Genetic Variations
  • Arctic and Antarctic ice dynamics
  • Environmental DNA in Biodiversity Studies
  • Marine and coastal plant biology
  • Indigenous Studies and Ecology
  • Species Distribution and Climate Change
  • Wildlife Ecology and Conservation
  • Amphibian and Reptile Biology
  • Aquaculture disease management and microbiota
  • Identification and Quantification in Food
  • Forensic and Genetic Research
  • Cell Adhesion Molecules Research
  • Planarian Biology and Electrostimulation
  • Ichthyology and Marine Biology
  • Marine and fisheries research
  • Marine Ecology and Invasive Species
  • Fish Ecology and Management Studies
  • Plant and animal studies
  • Animal Ecology and Behavior Studies
  • Helminth infection and control
  • Insect and Arachnid Ecology and Behavior

University of Oslo
2016-2025

Natural History Museum
2007-2024

Hasselt University
2024

Evolutionary Genomics (United States)
2023

Staatliches Naturhistorisches Museum
2015

American Museum of Natural History
2006-2013

Norwegian Polar Institute
2009-2010

UiT The Arctic University of Norway
2009-2010

University of Tübingen
1990-2009

German Oceanographic Museum
2009

We present an in silico approach for the reconstruction of complete mitochondrial genomes non-model organisms directly from next-generation sequencing (NGS) data-mitochondrial baiting and iterative mapping (MITObim). The method is straightforward even if only (i) distantly related or (ii) barcode sequences are available as starting-reference seeds, respectively. demonstrate efficiency case studies using real NGS data sets two monogenean ectoparasites species Gyrodactylus thymalli...

10.1093/nar/gkt371 article EN cc-by Nucleic Acids Research 2013-05-09

Polar bears (PBs) are superbly adapted to the extreme Arctic environment and have become emblematic of threat biodiversity from global climate change. Their divergence lower-latitude brown bear provides a textbook example rapid evolution distinct phenotypes. However, limited mitochondrial nuclear DNA evidence conflicts in timing PB origin as well placement species within versus sister lineage. We gathered extensive genomic sequence data contemporary polar, brown, American black samples,...

10.1073/pnas.1210506109 article EN Proceedings of the National Academy of Sciences 2012-07-23

Abstract Background Stress responses are key the survival of parasites and, consequently, also evolutionary success these organisms. Despite this importance, our understanding evolution molecular pathways dealing with environmental stressors in parasitic animals remains limited. Here, we tested link between adaptive parasite stress response genes and their ecological diversity species richness. We comparatively investigated antioxidant, heat shock, osmoregulatory, behaviour-related (...

10.1186/s12915-024-02091-w article EN cc-by BMC Biology 2025-01-13

The polar bear has become the flagship species in climate-change discussion. However, little is known about how past climate impacted its evolution and persistence, given an extremely poor fossil record. Although it undisputed from analyses of mitochondrial (mt) DNA that bears constitute a lineage within genetic diversity brown bears, timing estimates their divergence have differed considerably. Using next-generation sequencing technology, we generated complete, high-quality mt genome...

10.1073/pnas.0914266107 article EN Proceedings of the National Academy of Sciences 2010-03-01

The ectoparasitic Monogenea comprise a major part of the obligate parasitic flatworm diversity. Although genomic adaptations to parasitism have been studied in endoparasitic tapeworms (Cestoda) and flukes (Trematoda), no representative has investigated yet. We present high-quality draft genome Gyrodactylus salaris, an economically important monogenean ectoparasite wild Atlantic salmon (Salmo salar). A total 15,488 gene models were identified, which 7,102 functionally annotated. controversial...

10.1093/gbe/evu078 article EN cc-by-nc Genome Biology and Evolution 2014-04-14

North America is currently home to a number of grey wolf (Canis lupus) and wolf-like canid populations, including the coyote latrans) taxonomically controversial red, Eastern timber Great Lakes wolves. We explored their population structure regional gene flow using dataset 40 full genome sequences that represent extant diversity American wolves populations. This included 15 new genomes (13 wolves, 1 red timber/Great wolf), ranging from 0.4 15x coverage. In addition providing support for...

10.1371/journal.pgen.1007745 article EN cc-by PLoS Genetics 2018-11-12

Sled dog arctic adaptations go far back Dogs have been used for sledding in the Arctic as ∼9500 years ago. However, relationships among earliest sled dogs, other populations, and wolves are unknown. Sinding et al. sequenced an ancient dog, 10 modern wolf analyzed their genetic with dogs. This analysis indicates that dogs represent lineage going at least 9500 bred ancestors of precontact American gene flow between likely stopped before Science , this issue p. 1495

10.1126/science.aaz8599 article EN Science 2020-06-25

Recent studies on microRNA (miRNA) evolution focused mainly the comparison of miRNA complements between animal clades. However, miRNAs within such groups is poorly explored despite availability comparable data that in some cases lack only a few key taxa. For flatworms (Platyhelminthes), are available for free-living and all major parasitic lineages, except Monogenea. We present complement monogenean flatworm Gyrodactylus salaris facilitates comprehensive analysis Platyhelminthes. Using newly...

10.1093/molbev/mst155 article EN cc-by-nc Molecular Biology and Evolution 2013-09-11

Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of Inuit were first introduce widespread usage dog sledge transportation technology Americas, but whether adopted local Palaeo-Inuit or introduced a new population region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data skull dental elements from total 922 wolves spanning over 4500 years. Our analyses revealed that sites dating 2000 BP...

10.1098/rspb.2019.1929 article EN cc-by Proceedings of the Royal Society B Biological Sciences 2019-11-27

Extant Canis lupus genetic diversity can be grouped into three phylogenetically distinct clades: Eurasian and American wolves domestic dogs.1Fan Z. Silva P. Gronau I. Wang S. Armero A.S. Schweizer R.M. Ramirez O. Pollinger J. Galaverni M. Ortega Del-Vecchyo D. et al.Worldwide patterns of genomic variation admixture in gray wolves.Genome Res. 2016; 26: 163-173Crossref PubMed Scopus (125) Google Scholar Genetic studies have suggested these groups trace their origins to a wolf population that...

10.1016/j.cub.2020.10.002 article EN cc-by-nc-nd Current Biology 2020-10-30

Gyrodactylus thymalli Zitnan, 1960 and G. salaris Malmberg, 1957 have an indistinguishable ribosomal internal transcribed spacer (ITS) DNA sequence, but exhibit surprisingly high levels of intra- interspecific sequence variation the mitochondrial cytochrome oxidase I (CO1) gene. To test whether different populations these reportedly very similar species could be discriminated using morphometric methods, we examined morphometry four representing clades. Twenty five point-to-point...

10.14411/fp.2004.029 article EN Folia Parasitologica 2004-06-01

We provide an expansive analysis of polar bear (Ursus maritimus) circumpolar genetic variation during the last two decades decline in their sea-ice habitat. sought to evaluate whether diversity and structure have changed over this period habitat decline, how current patterns compare with past patterns, demography ancient fluctuations climate. Characterizing using microsatellite data, we defined four clusters that largely correspond ecological oceanographic factors: Eastern Polar Basin,...

10.1371/journal.pone.0112021 article EN cc-by PLoS ONE 2015-01-06

The polar bear ( Ursus maritimus ) has become a symbol of the threat to biodiversity from climate change. Understanding evolutionary history may provide insights into apex carnivore responses and prospects during periods extreme environmental perturbations. In recent years, genomic studies have examined speciation population history, including evidence for ancient admixture between bears brown arctos ). Here, we extend our earlier 130,000- 115,000-y-old Svalbard Archipelago using 10×...

10.1073/pnas.2200016119 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2022-06-06

Global warming is affecting the population dynamics and trophic interactions across a wide range of ecosystems habitats. Translating these real-time effects into their long-term consequences remains challenge. The rapid extreme period that occurred after Last Glacial Maximum (LGM) during Pleistocene-Holocene transition (7-12 thousand years ago) provides an opportunity to gain insights responses natural populations periods with global warming. this post-LGM have been assessed in many...

10.1111/gcb.16085 article EN cc-by Global Change Biology 2022-02-02

The highly repetitive satellite DNA family "ATOC180" is specific for the three closely related species Drosophila obscura, D. ambigua, and tristis but does not occur in their closest relatives subsilvestris bifasciata. Approximately 10,000 copies/haploid genome of approximately 180-bp repetition units are tandemly arranged centromeric heterochromatin all chromosomes species. Molecular analysis 29 cloned repeats shows much intra- interspecific sequence homogeneity. Single nucleotide changes...

10.1093/oxfordjournals.molbev.a040029 article EN Molecular Biology and Evolution 1993-05-01

This work reports the discovery and functional characterization of catalytically active hammerhead motifs within satellite DNA pDo500 family from several Dolichopoda cave cricket species. We show that in vitro transcribed RNA some members this do self-cleave vitro. self-cleavage activity is correlated with efficient vivo processing long primary transcripts into monomer-sized RNA. The high sequence conservation among genetically isolated schiavazzii populations, as well other species, along...

10.1093/nar/28.20.4037 article EN Nucleic Acids Research 2000-10-15

Microsatellites are frequently used genetic markers in a wide range of applications, primarily due to their high length polymorphism levels that can easily be genotyped by fragment analysis. However, the mode microsatellite evolution is yet not fully understood, and role interrupting motifs for stability microsatellites remains explored more detail. Here we present sequence analysis mutation events description structure repeated regions hypervariable, pentanucleotide locus HrU10 barn...

10.1186/1471-2148-8-138 article EN cc-by BMC Evolutionary Biology 2008-01-01

Abstract Using ancient DNA sequences of subfossil European pond turtles ( Emys orbicularis ) from Britain, Central and North Europe accelerator mass spectrometry radiocarbon dating for turtle remains most Swedish sites, we provide evidence a Holocene range expansion the southeastern Balkans into Scandinavia, according to ‘grasshopper pattern’ Hewitt. Northeastern adjacent Asia were colonized another refuge located further east. With increasing annual mean temperatures, reached southern...

10.1111/j.1365-294x.2009.04096.x article EN Molecular Ecology 2009-02-16

Polar bears ( Ursus maritimus Phipps, 1774) show fidelity to general denning areas in subsequent reproductive events. Studying the level and spatio-temporal scale of denning-area is critical determine adaptability polar climate change. We used mark–recapture data conjunction with mitochondrial DNA (mtDNA) investigate from Barents Sea population five maternal areas. There was no differentiation mtDNA haplotype frequencies between The females at a local geographic small groups neighboring...

10.1139/z10-078 article EN Canadian Journal of Zoology 2010-12-01
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