A5004677226- Human-Animal Interaction Studies
- Indigenous Studies and Ecology
- Forensic and Genetic Research
- Wildlife Ecology and Conservation
- Archaeology and ancient environmental studies
- Marine animal studies overview
- Yersinia bacterium, plague, ectoparasites research
- Genetic and phenotypic traits in livestock
- Pleistocene-Era Hominins and Archaeology
- Genetic diversity and population structure
- Isotope Analysis in Ecology
- Forensic Anthropology and Bioarchaeology Studies
- Environmental DNA in Biodiversity Studies
- Folklore, Mythology, and Literature Studies
- Animal Diversity and Health Studies
- Identification and Quantification in Food
- Photosynthetic Processes and Mechanisms
- Archaeological Research and Protection
- Plant Gene Expression Analysis
- Primate Behavior and Ecology
- Genetic Mapping and Diversity in Plants and Animals
- Evolution and Genetic Dynamics
- Plant Disease Resistance and Genetics
- Chromosomal and Genetic Variations
- Rabies epidemiology and control
National Institutes of Health
2023-2024
National Human Genome Research Institute
2023-2024
University of Copenhagen
2017-2023
Ilisimatusarfik
2019-2021
Swedish Museum of Natural History
2017-2021
Stockholm University
2019-2021
Centre for Palaeogenetics
2019-2021
University of Tübingen
2021
Studi
2019-2020
Max Planck Institute for Developmental Biology
2019
Advances in the isolation and sequencing of ancient DNA have begun to reveal population histories both people dogs. Over last 10,000 y, genetic signatures dog remains been linked with known human dispersals regions such as Arctic remote Pacific. It is suspected, however, that this relationship has a much deeper antiquity, tandem movement dogs may soon after domestication from gray wolf ancestor late Pleistocene. Here, by comparing results humans Siberia, Beringia, North America, we show...
Abstract The grey wolf ( Canis lupus ) was the first species to give rise a domestic population, and they remained widespread throughout last Ice Age when many other large mammal went extinct. Little is known, however, about history possible extinction of past populations or where progenitors present-day dog lineage familiaris lived 1–8 . Here we analysed 72 ancient genomes spanning 100,000 years from Europe, Siberia North America. We found that were highly connected Late Pleistocene, with...
Abstract Rowan et al. generated a dataset of over 17,000 meiotic crossovers (COs) from 2000 F2 individuals single Arabidopsis thaliana cross. The unprecedented density COs and the high-quality reference genomes two... Many environmental, genetic, epigenetic factors are known to affect frequency positioning (COs). Suppression by large, cytologically visible inversions translocations has long been recognized, but relatively little is about how smaller structural variants (SVs) COs. To examine...
Sled dog arctic adaptations go far back Dogs have been used for sledding in the Arctic as ∼9500 years ago. However, relationships among earliest sled dogs, other populations, and wolves are unknown. Sinding et al. sequenced an ancient dog, 10 modern wolf analyzed their genetic with dogs. This analysis indicates that dogs represent lineage going at least 9500 bred ancestors of precontact American gene flow between likely stopped before Science , this issue p. 1495
Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of Inuit were first introduce widespread usage dog sledge transportation technology Americas, but whether adopted local Palaeo-Inuit or introduced a new population region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data skull dental elements from total 922 wolves spanning over 4500 years. Our analyses revealed that sites dating 2000 BP...
Extant Canis lupus genetic diversity can be grouped into three phylogenetically distinct clades: Eurasian and American wolves domestic dogs.1Fan Z. Silva P. Gronau I. Wang S. Armero A.S. Schweizer R.M. Ramirez O. Pollinger J. Galaverni M. Ortega Del-Vecchyo D. et al.Worldwide patterns of genomic variation admixture in gray wolves.Genome Res. 2016; 26: 163-173Crossref PubMed Scopus (125) Google Scholar Genetic studies have suggested these groups trace their origins to a wolf population that...
Significance The Siberian Arctic has witnessed numerous societal changes since the first known appearance of dogs in region ∼10,000 years ago. These include introduction ironworking ∼2,000 ago and emergence reindeer pastoralism ∼800 analysis 49 ancient dog genomes reveals that ancestry Siberia shifted over last 2,000 due to an influx from Eurasian Steppe Europe. Combined with genomic data humans archaeological evidence, our results suggest though human populations did not change this period,...
Abstract Background After over a decade of developments in field collection, laboratory methods and advances high-throughput sequencing, contamination remains key issue ancient DNA research. Currently, human microbial contaminant still impose challenges on cost-effective sequencing accurate interpretation data. Results Here we investigate whether contaminating can be found faunal datasets. We identify variable levels contamination, which persists even after the sequence reads have been...
Abstract Dogs are known to be the oldest animals domesticated by humans. Although many studies have examined wolf domestication, geographic and temporal origin of this process is still being debated. To address issue, our study sheds new light on early stages domestication during Magdalenian period (16–14 ka cal BP) in Hegau Jura region (Southwestern Germany Switzerland). By combining morphology, genetics, isotopes, multidisciplinary approach helps evaluate alternate processes driving phases...
Ancestral Coast Salish societies in the Pacific Northwest kept long-haired "woolly dogs" that were bred and cared for over millennia. However, dog wool-weaving tradition declined during 19th century, population was lost. In this study, we analyzed genomic isotopic data from a preserved woolly pelt "Mutton," collected 1859. Mutton is only known example of an Indigenous North American with dominant precolonial ancestry postdating onset settler colonialism. We identified candidate genetic...
For at least 9000 years dogs have been pulling sleds across the Arctic, facilitating subsistence strategies and migrations. Despite enduring presence of in Arctic there is an absence comprehensive studies material culture associate with dog sledding, including diverse technical elements needed for activity. This study proposes a framework recognition reliable archaeological indicators sledding. The outcome based on comparisons between ethnographic information traction technology sites from...
Among Indigenous populations of the Arctic, domestic dogs (Canislupus familiaris) were social actors aiding in traction and subsistence activities. Less commonly, fulfilled a fur-bearing role both North American Siberian Arctic. Examples garments featuring dog skins collected during 19th-20th centuries are now curated by National Museum Denmark. We sequenced mitochondrial genomes macroscopically identified skin garments. conducted stable carbon nitrogen isotope ratio analysis furs fur...
The multi-millenia long history between dogs and humans has placed them at the forefront of archeological genomic research. Despite ongoing efforts including analysis ancient dog wolf genomes, many questions remain regarding their geographic temporal origins, microevolutionary processes that led to diversity breeds today. Although genomes provide valuable information, use is hindered by low depth coverage post-mortem damage, which inhibits confident genotype calling. In present study, we...
Abstract Background After over a decade of developments in field collection, laboratory methods and advances high-throughput sequencing, contamination remains key issue ancient DNA research. Currently, human microbial contaminant still impose challenges on cost-effective sequencing accurate interpretation data. Results Here we investigate whether contaminating can be found faunal datasets. We identify variable levels contamination, which persists even after the sequence reads have been...
Abstract Many environmental, genetic, and epigenetic factors are known to affect the frequency positioning of meiotic crossovers (COs). Suppression COs by large, cytologically visible inversions translocations has long been recognized, but relatively little is about how smaller structural variants (SVs) COs. To examine fine-scale determinants CO landscape, including SVs, we used a rapid, cost-effective method for high-throughput sequencing generate precise map over 17,000 between Col-0 Ler...
For at least 9000 years dogs have been pulling sleds across the Arctic, facilitating subsistence strategies and migrations. Despite enduring presence of in Arctic there is an absence comprehensive study material culture associate with dog sledding, including diverse technical elements needed for activity. Based on ethnographical observations traction technology, this proposes a framework recognition reliable archaeological indicators sledding. Archaeological sites from regions Siberia,...
For at least 9000 years dogs have been pulling sleds across the Arctic, facilitating subsistence strategies and migrations. Despite enduring presence of in Arctic there is an absence comprehensive studies material culture associate with dog sledding, including diverse technical elements needed for activity. Based on ethnographical observations traction technology, this study proposes a framework recognition reliable archaeological indicators sledding. Archaeological sites from regions...
For at least 9000 years dogs have been pulling sleds across the Arctic, facilitating subsistence strategies and migrations. Despite enduring presence of in Arctic there is an absence comprehensive studies material culture associate with dog sledding, including diverse technical elements needed for activity. This study proposes a framework recognition reliable archaeological indicators sledding. The outcome based on comparisons between ethnographic information traction technology sites from...