A5030383880- Pleistocene-Era Hominins and Archaeology
- Archaeology and ancient environmental studies
- Indigenous Studies and Ecology
- Geology and Paleoclimatology Research
- Wildlife Ecology and Conservation
- Forensic and Genetic Research
- Genetic diversity and population structure
- Evolution and Paleontology Studies
- Topic Modeling
- Natural Language Processing Techniques
- Paleopathology and ancient diseases
- Yersinia bacterium, plague, ectoparasites research
- Genomics and Phylogenetic Studies
- Animal Ecology and Behavior Studies
- Ecology and biodiversity studies
- Identification and Quantification in Food
- Marine animal studies overview
- Forensic Anthropology and Bioarchaeology Studies
- Isotope Analysis in Ecology
- Geological Studies and Exploration
- Environmental DNA in Biodiversity Studies
- Marine and environmental studies
- Climate change and permafrost
- Methane Hydrates and Related Phenomena
- Species Distribution and Climate Change
Zoological Institute
2014-2024
North-Eastern Federal University
2013-2024
Max Planck Institute for Mathematics in the Sciences
2022
University of Lisbon
2022
Max Planck Institute for Mathematics
2022
Russian Academy of Sciences
2009-2022
Leipzig University
2022
Moscow Aviation Institute
2022
Swedish Museum of Natural History
2018
University of Groningen
2004-2018
We sequenced 28 million base pairs of DNA in a metagenomics approach, using woolly mammoth (Mammuthus primigenius) sample from Siberia. As result exceptional preservation and the use recently developed emulsion polymerase chain reaction pyrosequencing technique, 13 (45.4%) sequencing reads were identified as DNA. Sequence identity between our data African elephant (Loxodonta africana) was 98.55%, consistent with paleontologically based divergence date 5 to 6 years. The includes surprisingly...
Although the application of sequencing-by-synthesis techniques to DNA extracted from bones has revolutionized study ancient DNA, it been plagued by large fractions contaminating environmental DNA. The genetic analyses hair shafts could be a solution: We present 10 previously unexamined Siberian mammoth (Mammuthus primigenius) mitochondrial genomes, sequenced with up 48-fold coverage. observed levels damage-derived sequencing errors were lower than those in published frozen bone samples, even...
The causes of the late Pleistocene megafaunal extinctions are poorly understood. Different lines evidence point to climate change, arrival humans, or a combination these events as trigger. Although many species went extinct, others, such caribou and bison, survived present. musk ox has an intermediate story: relatively abundant during Pleistocene, it is now restricted Greenland Arctic Archipelago. In this study, we use ancient DNA sequences, temporally unbiased summary statistics, Bayesian...
Epigenetic information is available from contemporary organisms, but difficult to track back in evolutionary time. Here, we show that genome-wide epigenetic can be gathered directly next-generation sequence reads of DNA isolated ancient remains. Using the genome data generated hair shafts a 4000-yr-old Paleo-Eskimo belonging Saqqaq culture, generate first nucleosome map coupled with survey cytosine methylation levels. The validity both and levels were confirmed by recovery expected signals...
We report five new complete mitochondrial DNA (mtDNA) genomes of Siberian woolly mammoth ( Mammuthus primigenius ), sequenced with up to 73-fold coverage from extracted hair shaft material. Three the sequences present first mtDNA clade II. Analysis these and 13 recently published demonstrates existence two apparently sympatric clades that exhibit high interclade divergence. The analytical power afforded by analysis reveals a surprisingly ancient coalescence age clades, ≈1–2 million years,...
Significance Yakutia is among the coldest regions in Northern Hemisphere, showing ∼40% of its territory above Arctic Circle. Native horses are particularly adapted to this environment, with body sizes and thick winter coats minimizing heat loss. We sequenced complete genomes two ancient nine present-day Yakutian elucidate their evolutionary origins. find that contemporary population descends from domestic livestock, likely brought by early horse-riders who settled region a few centuries ago....
Archaeological evidence for human dispersal through northern Eurasia before 40,000 years ago is rare. In west Siberia, the northernmost find of that age located at 57°N. Elsewhere, earliest presence humans in Arctic commonly thought to be circa 35,000 30,000 present. A mammoth kill site central Siberian Arctic, dated 45,000 present, expands populated area almost 72°N. The advancement hunting probably allowed people survive and spread widely across Siberia.
Abstract Uncertainty about the geological processes that deposited syngenetically frozen ice‐rich silt ( yedoma ) across hundreds of thousands square kilometres in central and northern Siberia fundamentally limits our understanding Pleistocene geology palaeoecology western Beringia, sedimentary led to sequestration Pg carbon within permafrost whether provides a globally significant record ice‐age atmospheric conditions or just regional floodplain activity. Here, we test hypotheses aeolian...
Part of a large male woolly mammoth ( Mammuthus primigenius ) was preserved in permafrost northern Yakutia. It radiocarbon dated to ca. 18,500 14 C yr BP (ca. 22,500 cal BP). Dung from the lower intestine subjected multiproxy array microscopic, chemical, and molecular techniques reconstruct diet, season death, paleoenvironment. Pollen plant macro-remains showed that grasses sedges were main food, with considerable amounts dwarf willow twigs variety herbs mosses. Analyses 110-bp fragments...
Abstract A megaslump at Batagaika, in northern Yakutia, exposes a remarkable stratigraphic sequence of permafrost deposits ~50–80 m thick. To determine their potential for answering key questions about Quaternary environmental and climatic change northeast Siberia, we carried out reconnaissance study cryostratigraphy paleoecology, supported by four rangefinder 14 C ages. The includes two ice complexes separated unit fine sand containing narrow syngenetic wedges multiple paleosols. Overall,...
Ancient genomes provide a tool to investigate the genetic basis of adaptations in extinct organisms. However, identification species-specific fixed variants requires analysis from multiple individuals. Moreover, long-term scale adaptive evolution coupled with short-term nature traditional time series data has made it difficult assess when different evolved. Here, we analyze 23 woolly mammoth genomes, including one oldest known specimens at 700,000 years old, identify derived non-synonymous...
A number of species have recently recovered from near-extinction. Although these avoided the immediate extinction threat, their long-term viability remains precarious due to potential genetic consequences population declines, which are poorly understood on a timescale beyond few generations. Woolly mammoths (Mammuthus primigenius) became isolated Wrangel Island around 10,000 years ago and persisted for over 200 generations before becoming extinct 4,000 ago. To study evolutionary processes...
Abstract The recent discovery that DNA methylation survives in fossil material provides an opportunity for novel molecular approaches palaeogenomics. Here, we apply to ancient extracts the probe-independent Methylated Binding Domains (MBD)-based enrichment method, which targets molecules containing methylated CpGs. Using remains of a Palaeo-Eskimo Saqqaq individual, woolly mammoths, polar bears and two equine species, confirm variety tissues, environmental contexts over large temporal range...
Abstract Near the end of Pleistocene epoch, populations woolly mammoth ( Mammuthus primigenius ) were distributed across parts three continents, from western Europe and northern Asia through Beringia to Atlantic seaboard North America. Nonetheless, questions about connectivity temporal continuity species remain unanswered. We use a combination targeted enrichment high-throughput sequencing assemble interpret data set 143 mitochondrial genomes, sampled fossils recovered their Holarctic range....
Abstract Prior to the Holocene, range of saiga antelope ( Saiga tatarica ) spanned from France Northwest Territories Canada. Although its distribution subsequently contracted steppes Central Asia, historical records indicate that it remained extremely abundant until end Soviet Union, after which populations were reduced by over 95%. We have analysed mitochondrial control region sequence variation 27 ancient and 38 modern specimens, assay how species’ genetic diversity has changed since...