- Cervical Cancer and HPV Research
- AI in cancer detection
- Radiology practices and education
- Biomedical and Engineering Education
- Social Media in Health Education
- Global Cancer Incidence and Screening
- Advances in Oncology and Radiotherapy
- Genetics, Bioinformatics, and Biomedical Research
- Colorectal Cancer Screening and Detection
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Ethics in Clinical Research
- Philosophy and Literary Analysis
- Dendrimers and Hyperbranched Polymers
- Cancer Genomics and Diagnostics
- Cell Image Analysis Techniques
- Radiomics and Machine Learning in Medical Imaging
- Simulation-Based Education in Healthcare
- Pancreatic and Hepatic Oncology Research
- Radio, Podcasts, and Digital Media
- Interprofessional Education and Collaboration
- Multimedia Communication and Technology
- Bartonella species infections research
- Reliability and Agreement in Measurement
- Vector-borne infectious diseases
University of Nebraska Medical Center
2014-2024
University of Leicester
2023-2024
Nebraska Medical Center
2017-2024
University of Iowa
1995-2007
Kaiser Permanente
2006
University of Pittsburgh Medical Center
2006
University of Iowa Hospitals and Clinics
1999
British Glass
1997
The integration of whole slide imaging (WSI) and artificial intelligence (AI) with digital cytology has been growing gradually. Therefore, there is a need to evaluate the current state cytology. This study aimed determine landscape via survey conducted as part American Society Cytopathology (ASC) Digital Cytology White Paper Task Force. A 43 questions pertaining practices experiences WSI AI in both surgical pathology was created. sent members ASC, International Academy (IAC), Papanicolaou...
Here, we present a cross-linking approach to covalently functionalize and stabilize DNA origami structures in one-pot reaction. Our strategy involves adding nucleotide sequences adjacent staple strands, so that, upon assembly of the structure, extensions form short hairpin duplexes targetable by psoralen-labeled triplex-forming oligonucleotides bearing other functional groups (pso-TFOs). Subsequent irradiation with UVA light generates psoralen adducts one or both staples leading...
Clear cell tumors (CCTs) occur as primary neoplasms in a number of anatomic sites. Due to their overlapping morphologic features, these can be challenging for the cytologist, particularly when they present metastatic lesions.Forty-nine fine-needle aspirations (FNA) CCTs from 46 patients (age range, 29-87 years; mean, 64 years) were reviewed retrospectively. In addition routine smears and block preparations, ancillary studies performed selected cases. Clinical and/or histologic follow-up was...
Papanicolaou screening is feasible anywhere that for cervical cancer, the leading cause of cancer-related death among women in developing countries, appropriate. After documenting Vietnam War had contributed to problem cancer Vietnam, we participated a grass roots effort establish nationwide prevention program country and performed root analyses deficiencies. We found real-world obstacles successful countries involve people far more than technology such can be appropriately managed through...
The use of virtual microscopy (VM) in clinical cytology has been limited due to the inability focus through three dimensional (3D) cell clusters with a single focal plane (2D images). Limited information exists regarding optimal scanning parameters for 3D scanning.The purpose this study was determine number levels and interval digitize gynecological (GYN) specimens prepared on SurePath™ glass slides while maintaining manageable file size.The iScanCoreo Au scanner (Ventana, AZ, USA) used 192...
<b><i>Objective:</i></b> The aim of this work was to raise awareness problems using digital applications for examining, teaching, and applying telecytology at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia; University Nebraska Center (UNMC), Omaha, NE, USA; Pittsburgh (UPMC), Pittsburgh, PA, USA. objective rationalize propose alternative approaches. <b><i>Study Design:</i></b> We sought identify solutions improve the following: (a)...
To evaluate the effectiveness of 3-D vs. 2-D virtual microscopy as adjuncts to education and assessment in cervical cytology.Five cytology slides were acquired 2-D; then identical area slide was 3-D, resulting 2 sets for comparison with original glass slide. Seventy-nine paid volunteer cytologists cytotechnology students participated. Approximately half sent set via Web, others a on DVD. Evaluators examined committed an interpretation. After receipt slides, second interpretation made, if...
Background: Virtual microscopy (VM) is a technology in which the glass slides are converted into digital images. The main objective of this study to determine if cellular morphology, learned through virtual microscopy, can be applied slide screening. Materials and Methods: A total 142 (61 teaching 81 practice) breast, thyroid, lymph node fine needle aspiration body sites were scanned with single focal plane (at 40X) using iScanCoreo Au (Ventana, Tuscan, AZ, USA, formerly known as BioImagene,...
The shift to digital learning in medicine is well underway and fact spurred by the COVID-19 pandemic. didactic portion of our institution's cytotechnology (CT) education program online delivered learners across nation. With CT elevating master's degree level, there a need expand cytologic correlation with surgical resection specimens. We also wanted afford pathology residents same. developed an cytologic-histologic module (e-module) addressing thyroid fine needle aspirations (FNAs)...
Background: Our cytotechnology (CT) program has been utilizing virtual microscopy (VM) as an adjunct educational resource since 2011. Aims: The aim of this study was to identify the utilization VM in other CT programs across United States (US). Subjects and Methods: A cover letter sent directors all accredited US (excluding our program), requesting their participation online survey. After 2 days, participants were link survey results analyzed using descriptive statistics. Results: There a...
Background: Interest in developing more feasible and affordable applications of virtual microscopy the field cytology continues to grow. Aims: The aim this study was investigate scanning parameters for thyroid fine needle aspiration (FNA) specimens. Subjects Methods: A total twelve glass slides from FNA specimens were digitized at ×40 with 1 micron (μ) interval using seven focal plane (FP) levels (Group 1), five FP 2), three 3) iScan Coreo Au scanner (Ventana, AZ, USA) producing 36 images...
Cat scratch disease (CSD) is usually a benign, self-limited lymphadenitis, characterized by suppurative granulomas. It can, however, produce wide spectrum of clinical symptoms and cytologic changes be the source diagnostic dilemmas. Identification pleomorphic bacilli (PB) with silver impregnation stains aids in diagnosis, but this has not been well documented preparations or cases without classic morphologic changes. We reviewed 13 aspirations from eight patients (aged 13-36 yr) occurring...
Abstract The debate over the best route for cervical cancer prevention in developing countries may be considered part of a larger whether global health community has become enamored with promise new approaches at expense delivering available preventives today. Pap screening, which is feasible anywhere screening appropriate, only intervention currently countries, and test will an essential component future novel preventive approaches. Cervical vaccination, long‐term effectiveness uncertain,...
Background: Nine E-learning modules (ELMs) were developed in our program using Articulate software. This study assessed cytotechnology (CT) students’ perceptions on the content of ELMs, and perceived influence ELMs performance during clinical rotations. Subjects Methods: All CT students watched nine before related classroom lecture group discussion. Following that, completed preclinical rotation surveys. After their rotations, postclinical Results: Statements regarding quality video audio,...
'Morph' means to change gradually and completely from one thing into another usually in a way that is surprising or seems magical. How can cytotechnology education be morphed an expanded curriculum teach new skills for advanced practice? The challenges programmes are facing today many. biggest of these the decreasing volume Pap tests. tests have been our 'bread butter' throughout history; however, advances health care technology inevitable, thus requiring changes educational practices. While...