A5046229125- Neuroblastoma Research and Treatments
- Hernia repair and management
- Glioma Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Gastrointestinal disorders and treatments
- Injury Epidemiology and Prevention
- Congenital Diaphragmatic Hernia Studies
- Disaster Response and Management
- Esophageal and GI Pathology
- Healthcare Technology and Patient Monitoring
- Quality and Safety in Healthcare
- Abdominal Surgery and Complications
- Asthma and respiratory diseases
- Pediatric Hepatobiliary Diseases and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Dysphagia Assessment and Management
- Appendicitis Diagnosis and Management
- Advanced Breast Cancer Therapies
- Pediatric Pain Management Techniques
- Intestinal and Peritoneal Adhesions
- Simulation-Based Education in Healthcare
- Vascular Malformations and Hemangiomas
- Anorectal Disease Treatments and Outcomes
- Clinical Nutrition and Gastroenterology
- Suicide and Self-Harm Studies
University of Southern California
2017-2024
Children's Hospital of Los Angeles
2017-2020
Dana-Farber Cancer Institute
2018
Massachusetts General Hospital
2018
Nanostring Technologies (United States)
2018
Memorial Sloan Kettering Cancer Center
2018
Tennessee Oncology
2018
Duke University
2018
Dana-Farber Brigham Cancer Center
2018
Brigham and Women's Hospital
2018
Immunotherapy of neuroblastoma that remains after myeloablative chemotherapy with anti-GD2 antibody dinutuximab has increased the two-year event-free and overall survival high-risk patients; however, 40% patients develop recurrent disease during or this treatment. To determine potential such antibody-based immunotherapy earlier in treatment, a mouse model was developed which surgical resection primary tumor followed by therapy residual combined ex vivo-activated human natural killer (aNK)...
Abstract Background To better characterize short‐term and long‐term outcomes in children with pancreatic tumors treated pancreaticoduodenectomy (PD). Methods Patients 21 years of age or younger who underwent PD at Pediatric Surgical Oncology Collaborative (PSORC) hospitals between 1990 2017 were identified. Demographic, clinical information, (operative complications, function, recurrence, survival) collected. Results Sixty‐five patients from 18 institutions a median 13 (4 months‐22 years)...
Meckel's diverticula are common congenital gastrointestinal malformations that most often present with bloody stool or bowel obstruction. Occasionally these may become inverted and serve as a lead point for the development of intussusception. Herein, we report case 10-year old female presenting abdominal pain non-bloody, non-bilious emesis suspicion Upon performing an exploratory laparotomy, intussusception was found to be diverticulum obstructing lumen intestine.
Apprehension in taking independent care of children with medical devices may lead to unnecessary visits the ED and/or acute clinic (AC). To address these concerns, our institution implemented a gastrostomy tube (GT) class 2011 for caretakers. We hypothesized that inappropriate GT-related ED/AC would be lower preoperatively educated caregivers. performed retrospective cohort study all patients aged 0 18 who received GT (surgical or percutaneous) at between 2006 and 2015 (n = 1340). Class...
To describe utilization and long-term outcomes of pneumonectomy in children adolescents with cancer.Pneumonectomy adults is associated significant morbidity mortality. Little known about the indications for pediatric tumors.The Pediatric Surgical Oncology Research Collaborative (PSORC) identified patients <21 years age who underwent from 1990 to 2017 primary or metastatic tumors at 12 institutions. Clinical information was collected; included operative complications, function, recurrence,...
Abstract Gastric surgery may result in internal herniation of bowel, weeks to years after the initial and can rapid onset death if not promptly treated. We present a case which patient with this complication underwent despite his clear refusal surgery. The had remote history gastrectomy for malignancy. Several later, he presented feared an local hospital. surgeon recommended urgent operation correct this. However, refused. When became comatose, performed surgery, but patient’s condition...
Perianal abscess and fistula-in-ano are well-described in the pediatric population. They most common infants less than 1 year of age often resolve with oral antibiotics; occasionally they require drainage or fistulotomy. The etiology is commonly associated cryptoglandular obstruction subsequent infection, however alternative diagnoses should be considered cases recurrent abscesses fistulae that refractory to standard treatments. In this report, we present case an 8-year-old boy a complex,...
Complications subsequent to repair of a congenital tracheoesophageal fistula (TEF) with esophageal atresia (EA) include leak at the anastomosis, stricture formation, and recurrent fistula. Recurrence is uncommon, optimal management for debatable. As many symptoms TEF recurrence are similar common postoperative sequelae, diagnosis these recurrences can be quite challenging. We report case 12 year old patient history Type B EA/TEF (proximal pouch fistula, distal atresia) who was discovered...
Abstract Background: APT is a single arm multicenter, phase II study of paclitaxel and trastuzumab. Patients with HER2+ breast cancer negative nodes tumor size &lt; 3 cm were eligible. Disease-free survival at 7 years was 93.3% only 4 distant recurrences. Characterizing intrinsic subtype immune profiles these smaller tumors may help us better understand if the biology different than larger that have been previously characterized. Methods: Intrinsic subtyping by PAM50 signatures PanCancer...
<p>GD2 expression levels</p>
<p>Supplemental Figure 1</p>
<div>AbstractPurpose:<p>Immunotherapy of neuroblastoma that remains after myeloablative chemotherapy with anti-GD2 antibody dinutuximab has increased the two-year event-free and overall survival high-risk patients; however, 40% patients develop recurrent disease during or this treatment. To determine potential such antibody-based immunotherapy earlier in treatment, a mouse model was developed which surgical resection primary tumor followed by therapy residual combined <i>ex...
<div>AbstractPurpose:<p>Immunotherapy of neuroblastoma that remains after myeloablative chemotherapy with anti-GD2 antibody dinutuximab has increased the two-year event-free and overall survival high-risk patients; however, 40% patients develop recurrent disease during or this treatment. To determine potential such antibody-based immunotherapy earlier in treatment, a mouse model was developed which surgical resection primary tumor followed by therapy residual combined <i>ex...