A5041979740- Appendicitis Diagnosis and Management
- Intestinal Malrotation and Obstruction Disorders
- Congenital Diaphragmatic Hernia Studies
- Hernia repair and management
- Pediatric Pain Management Techniques
- Intraperitoneal and Appendiceal Malignancies
- Pancreatic and Hepatic Oncology Research
- Neuroblastoma Research and Treatments
- Innovations in Medical Education
- Neonatal Respiratory Health Research
- Congenital Anomalies and Fetal Surgery
- Surgical Simulation and Training
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Neuroendocrine Tumor Research Advances
- Anesthesia and Pain Management
- Gallbladder and Bile Duct Disorders
- Pediatric Urology and Nephrology Studies
- Gastrointestinal disorders and treatments
- Anorectal Disease Treatments and Outcomes
- Congenital Heart Disease Studies
- Abdominal Surgery and Complications
- Nosocomial Infections in ICU
- Viral-associated cancers and disorders
- Pediatric Hepatobiliary Diseases and Treatments
London Health Sciences Centre
2015-2025
Western University
2015-2024
Children's Hospital of Western Ontario
2009-2023
Lawson Health Research Institute
2023
Children’s Health Research Institute
2015-2023
Alberta Children's Hospital
2020
Women and Children’s Health Research Institute
2020
University of Alberta
2020
British Columbia Children's Hospital
2019
Western University of Health Sciences
2014-2016
<h3>Background</h3> Appendectomy is considered the gold standard treatment for acute appendicitis. Recently need surgery has been challenged in both adults and children. In children there growing clinician, patient parental interest non-operative of appendicitis with antibiotics as opposed to surgery. To date no multicentre randomised controlled trials that are appropriately powered determine efficacy (antibiotics) compared (appendectomy) have performed. <h3>Methods</h3> Multicentre,...
Abstract Background Image‐guided percutaneous core needle biopsy (PCNB) is increasingly utilized to diagnose solid tumors. The objective of this study determine whether PCNB adequate for modern biologic characterization neuroblastoma. Procedure A multi‐institutional retrospective was performed by the Pediatric Surgical Oncology Research Collaborative on children with neuroblastoma at 12 institutions over a 3‐year period. Data collected included demographics, clinical details, technique,...
Complete surgical resection of pulmonary metastatic disease in patients with osteosarcoma is crucial to long-term survival. Open thoracotomy allows palpation nodules not identified on imaging but the impact survival unknown. The objective this study was compare overall (OS) and disease-free (DFS) children who underwent vs thoracoscopic surgery for metastasectomy. A multi-institutional collaborative group retrospectively reviewed 202 pediatric metastasectomy by (n = 154) or thoracoscopy 48)....
Undifferentiated embryonal sarcoma of the liver (UESL) is a rare tumor for which there are few evidence-based guidelines. The aim this study was to define current management strategies and outcomes these patients using multi-institutional dataset curated by Pediatric Surgical Oncology Research Collaborative.
Background: The support for treatment of uncomplicated appendicitis with non-operative management as opposed to surgery has been building in the literature. We conducted a randomized trial compare failure rates.Methods: pragmatic multicenter, parallel-group, unmasked, non-inferiority, completed at 11 children's hospitals across globe. used non-inferiority design margin 20%, and 1:1 allocation while stratifying by sex, institution duration symptoms (≥ 48 hours verses <48 hours). Patients were...
Inflammatory myofibroblastic tumor (IMT) is a mesenchymal neoplasm of intermediate malignancy. We describe the largest cohort IMT patients to date, aiming further characterize this rare, poorly understood tumor. This multi-institutional review ≤39 years, from 2000 2018, at 18 hospitals in Pediatric Surgical Oncology Research Collaborative. One hundred and eighty-two were identified with median age 11 years. Thirty-three percent tumors thoracic origin. Presenting signs/symptoms included pain...
Pilonidal disease is a chronic, acquired inflammatory process of the skin due to entrapped hair at natal cleft. Reported recurrence rates are as high 30%, and has been attributed persistent near surgical site. Although conservative measures, such meticulous control improved perineal hygiene, have shown be effective, these techniques typically require much effort on behalf patient. Laser epilation (LE) might solve this issue poor patient compliance while helping patients avoid excision. In...
<h3>Background:</h3> This study describes our experience with the placement of a skin-level gastrostomy device (MIC-KEY) in single procedure. <h3>Methods:</h3> We identified infants, children and young adults who underwent laparoscopic-assisted percutaneous endoscopic (LAPEG) tube insertion between October 2009 June 2013. The steps this procedure include upper endoscopy, single-port laparoscopy, gastropexy via T-fasteners using "push" technique tear-away sheath. <h3>Results:</h3> included 92...
Abstract Background To better characterize short‐term and long‐term outcomes in children with pancreatic tumors treated pancreaticoduodenectomy (PD). Methods Patients 21 years of age or younger who underwent PD at Pediatric Surgical Oncology Collaborative (PSORC) hospitals between 1990 2017 were identified. Demographic, clinical information, (operative complications, function, recurrence, survival) collected. Results Sixty‐five patients from 18 institutions a median 13 (4 months‐22 years)...
Objective: To determine the impact of tumor characteristics and treatment approach on (1) local recurrence, (2) scoliosis development, (3) patient-reported quality life in children with sarcoma chest wall. Summary Background Data: Children wall require multimodal therapy including chemotherapy, surgery, and/or radiation. Despite aggressive which places them at risk for functional impairment scoliosis, these patients are also significant recurrence. Methods: A multi-institutional review 175...