Ying Lyu

ORCID: 0000-0001-7532-928X
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal disorders and treatments
  • Pancreatic and Hepatic Oncology Research
  • Gastrointestinal Tumor Research and Treatment
  • Pancreatitis Pathology and Treatment
  • Metastasis and carcinoma case studies
  • SARS-CoV-2 and COVID-19 Research
  • Breastfeeding Practices and Influences
  • Esophageal Cancer Research and Treatment
  • Gestational Diabetes Research and Management
  • Tryptophan and brain disorders
  • COVID-19 Clinical Research Studies
  • Infant Nutrition and Health
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Esophageal and GI Pathology
  • Diverticular Disease and Complications
  • Congenital Diaphragmatic Hernia Studies
  • Cancer-related molecular mechanisms research
  • Corneal Surgery and Treatments
  • Neonatal Respiratory Health Research
  • Lung Cancer Diagnosis and Treatment
  • Congenital Heart Disease Studies
  • Birth, Development, and Health
  • Glaucoma and retinal disorders
  • IgG4-Related and Inflammatory Diseases

Dongguan People’s Hospital
2025

Xian Center for Disease Control and Prevention
2025

Qiqihar Medical University
2024

Beihang University
2024

Peking University
2016-2024

Shanghai Jiao Tong University
2024

Tongren Hospital
2024

Beijing Hospital
2024

Chinese Center For Disease Control and Prevention
2022

Nanjing Drum Tower Hospital
2019-2022

Recent studies have reported a strong association between gestational diabetes mellitus (GDM) and postpartum depression (PPD), but little is known about the underlying physiological mechanism. In this study, GDM rat model was used to evaluate direct effect of on PPD explore After parturition, dams were divided into two groups: blood glucose not recovered group (GH group) (GL group). Fasting plasma (FPG), cortisol (COR) serotonin (5-hydroxytryptamine, 5-HT) metabolism continuously monitored...

10.3390/nu14061229 article EN Nutrients 2022-03-14

Objective: To investigate the safety of tetravalent meningococcal conjugate vaccine (MPCV-ACYW) in combination with inactivated poliomyelitis (IPV) and diphtheria-tetanus-acellular pertussis (DTaP) for infants aged 3-5 months provide real-world evidence immunization strategy combination. Methods: From June to October 2023, a total 600 3-month-old were selected divided into three groups: control group, mono-vaccination group combined vaccination group. They simultaneously or individually...

10.3760/cma.j.cn112150-20240815-00658 article EN PubMed 2025-01-24

Ulcerative colitis (UC) is non-specific inflammatory bowel disease. UC development and progression were closely associated with epigenetic modifications. Nevertheless, the specific relationship between N6-methyladenosine (m6A) modification at RNA transcription levels pathogenesis remains unclear. We established cell models mouse through dextran sulfate sodium (DSS) induction. The expression of METTL14 analyzed via qRT-PCR western blot. In vitro functional experiments evaluated effects...

10.1186/s40001-025-02334-8 article EN cc-by-nc-nd European journal of medical research 2025-02-08

Background and purpose Low serum levels of vitamin D have been associated with depression in non‐stroke subjects. Our aim was to examine the possible association between development post‐stroke ( PSD ). Methods In total, 189 patients acute ischaemic stroke were consecutively recruited. Serum 25‐hydroxyvitamin [25( OH ) ] measured by competitive protein‐binding assay within 24 h after admission. The 17‐item H amilton epression S cale used for screening existence depressive symptoms at 1 month...

10.1111/ene.12607 article EN European Journal of Neurology 2014-12-02

Adipocytes might arise from vascular stromal cells, pericytes and endothelia within adipose tissue or bone marrow cells resident in nonadipose tissue. Here, we identified precursor fascia, an uninterrupted sheet of connective that extends throughout the body. The fragments superficial fascia rat hindlimb were highly capable spontaneous induced adipogenic differentiation but not myogenic osteogenic differentiation. Fascial preadipocytes expressed multiple markers progenitors, similar to...

10.1002/stem.2338 article EN Stem Cells 2016-02-11

BACKGROUND:We aimed to investigate the prevalence trends and explore influencing factors of post-stroke depression based on National Health Nutrition Examination Survey (NHANES) database, including data from 2005 2018. MATERIAL AND METHODS:A total 1298 patients with stroke were included in this study. Multivariate logistic regression analysis was performed select factors. Subgroup conducted different populations. The odds ratio (OR) 95% confidence interval (CI) calculated. RESULTS:The 16.35%...

10.12659/msm.933367 article EN Medical Science Monitor 2021-11-22

Aged adults are prone to both short- and long-term complications following sepsis due ineffective therapy. Phosphatidylserine (PS) is a membrane nutrient supplement known enhance cognition brain function, but its potential effects in treating not well-documented. Our study aimed explore the of PS improving outcomes sepsis-associated encephalopathy (SAE). Middle-aged mice were administered for two months induction by lipopolysaccharides. The results indicated significant increase survival...

10.1016/j.biopha.2024.117200 article EN Biomedicine & Pharmacotherapy 2024-07-24

This study was designed to identify serum and amniotic fluid (AF) metabolic profile changes in response gestational diabetes mellitus (GDM) explore the association with maternal–fetal outcomes. We established GDM rat models by combining a high-fat diet (HFD) an injection of low-dose streptozotocin (STZ), detected fasting plasma glucose (FPG) pregnant rats second third trimester, collected AF fetal cesarean section on day 19 (GD19), as well measuring weight crown–rump length (CRL) rats....

10.3390/nu13103644 article EN Nutrients 2021-10-18

The study was designed to develop and validate the nutrition literacy assessment instrument for pregnant women in China (NLAI-P). dimension, components questions of NLAI-P were identified via literature review expert consultation. A panel experts evaluated content validity. construct validity by using exploratory factor analyses (EFA) confirmatory (CFA). Cronbach's α coefficient split-half reliability applied examining reliability. divided into 3 dimensions including knowledge, behavior...

10.3390/nu14142863 article EN Nutrients 2022-07-13

Objectives Endoscopic ultrasound‐guided gastroenterostomy (EUS‐GE) has recently been employed as a novel treatment for gastric outlet obstruction (GOO). The aim of this study was to evaluate the safety and efficacy EUS‐GE GOO at different sites. Methods Consecutive hospitalized patients who underwent Department Gastroenterology, Nanjing Drum Tower Hospital from March 2017 April 2020 were recruited in retrospective study. Patients divided into three groups depending on site. primary outcomes...

10.1111/1751-2980.13118 article EN Journal of Digestive Diseases 2022-07-01

To investigate the value of implantable cardiac monitor (ICM) in diagnosis and treatment patients over 60 years old with unexplained syncope.

10.3760/cma.j.cn112148-20230906-00132 article EN PubMed 2024-07-24

Abstract Work-Integrated Learning (WIL) has gained global attention as a means of enhancing graduates' employability and learning outcomes. In China, WIL been identified national strategy to elevate the quality engineering education. This study investigates effectiveness French education model internships in unique cultural educational landscape China by examining perceptions Chinese students enrolled Sino-French program. Grounded views situated learning, research explores role students'...

10.18260/1-2--47205 article EN 2024-08-04

Objective To study the risk factors for pathological upgrading after diagnosis of esophageal low-grade intra-epithelial neoplasia with ESD preoperative biopsy. Methods The endoscopic and data 85 lesions biopsy were analyzed, grouped based on ESD.The was studied through single multiple factor analysis. Results Pathological occurred in 45(52.94%) ESD, among whom 38 developed up to high-grade 7 early cancer. NBI-ME performed 37 patients accuracy detecting invasion 83.8%(31/37)....

10.3760/cma.j.issn.1007-5232.2016.06.003 article EN Zhonghua xiaohua neijing zazhi 2016-06-20

Objective To identify the risk factors for positive resection residues after endoscopic submucosal dissection(ESD) of early esophageal squamous carcinomas and precancerous lesions. Methods A retrospective analysis was performed in 315 patients with cancer lesion who underwent ESD.The pathological features all margins specimen follow-up outcome margin were evaluated. Univariate multivariate used to determine ESD. Results In lesions, there 290 lesions negative 25 margins.The...

10.3760/cma.j.issn.1007-5232.2016.07.007 article EN Zhonghua xiaohua neijing zazhi 2016-07-20

Objective To evaluate preoperative endoscopic ultrasonography(EUS)for diagnosis and invasive risk assessment of gastric gastrointestinal stromal tumors(GISTs). Methods A total 248 patients diagnosed as having GISTs based on EUS with established pathologic results at our institution were recruited to the study. The coincidence rates for between calculated. Univariate multivariate analyses used explore possible predictors rates. features compared according histological classification...

10.3760/cma.j.issn.1007-5232.2015.06.002 article EN Zhonghua xiaohua neijing zazhi 2015-06-20

Objective To assess the application value of lumen-apposing, fully covered, self-expandable metal stent (LAMS) in treatment peripancreatic fluid collection (PFC). Methods From July 2015 to 2017, at Drum Tower Hospital Affiliated Medical School Nanjing University, patients with PFC who received LAMS under endoscopic ultrasound were enrolled. The inclusion criteria was first treatment, age ≥18 years old, diameter >6 cm and clinical manifestations compression, or increased after...

10.3760/cma.j.issn.0254-1432.2018.10.006 article EN Zhonghua xiaohua zazhi 2018-10-15
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